@sussexbcr
A network of research groups across the University of Sussex, Brighton & Sussex Medical School and University Hospitals Sussex NHS trust investigating the causes of blood cancers, and developing new therapeutic strategies to improve patient survival.
Network opportunity!
3 year @cancerresearchuk.org funded Research Fellow post in the @rhysmorganlab.bsky.social in @biochembiomeduos.bsky.social alongside David Palmer in @bsmsmedschool.bsky.social working on RUNX1 mutations in CML.
Deadline Mar 8th. Applyπfor mid-Mar interviews and May start date
We're hiring a new 3 yr postdoc!
Join us for an exciting new CRUK funded project targeting RUNX1 mutations in CML in a highly supportive environment within @sussexbcr.bsky.social @biochembiomeduos.bsky.social @sussexcancer.org
Applyπ, advert closes 8th March.
jobs.sussex.ac.uk/job/4fee4e78...
Good news Friday!
Congratulations to @rhysmorganlab.bsky.social in @biochembiomeduos.bsky.social @sussex.ac.uk who have received their first funding from @cancerresearchuk.org with @uhsussex.bsky.social Clinical Fellow Dr David Palmer to progress their studies targeting RUNX1 mutations in CML. π
Beyond pleased to announce our lab has secured its first @cancerresearchuk.org funding with an Early Detection & Diagnosis Project Award titled:
'Detecting and targeting translation inhibitor sensitive RUNX1 mutations in Chronic Myeloid Leukaemia'
1/5
www.cancerresearchuk.org/for-research...
ποΈ New pre-print postedποΈ
Dr Okan Sevim from @rhysmorganlab.bsky.social @biochembiomeduos.bsky.social @sussex.ac.uk begins the publication of his doctoral work examining Wnt/B-catenin crosstalk with the RNA Binding Protein LIN28B and its potential for dual drug targeting in acute myeloid leukaemia. π
Very pleased to share our latest pre-print which showcases the incredible hard work and skill of Dr Okan Sevim.
Our continued exploration of Ξ²-catenin's contribution to the post transcriptional landscape of blood cells led us to a LIN28B interaction.
1/7
www.biorxiv.org/content/10.6...
πNew network opportunity!π
Prof @mitchell.science at @bsmsmedschool.bsky.social is advertising a new 3yr @leukaemiauk.bsky.social funded PDRA using mechanistic models to identify B-cell lymphoma therapeutic vulnerabilities.
Expected start date: Aprilβ26
Applyπby 01/03/2026 and join Sussex BCR!
Weβre excited to announce that weβre looking for a postdoctoral research to join our team!
This is an opportunity to lead an exciting project aiming to push the boundaries of personalised medicine through integrating data, simulation and lab experiments.
Plz share
mitchell.science/talk/we-are-...
Many thanks to all the co-authors at @sussexbcr.bsky.social @bsmsmedschool.bsky.social
@sussex.ac.uk @sussexcancer.org @biochembiomeduos.bsky.social @ox.ac.uk who contributed to the study, funders for kindly supporting our work, and all our patients who selflessly donate samples for research.
7/7
We now have a LinkedIn page!
Please follow for the latest updates on research funding, publications, events, scientific/clinical discoveries and job vacancies!
www.linkedin.com/in/sussex-bl...
Happy new year from Sussex Blood Cancer Research!
If youβre an ambitious haematology scientist/clinician seeking Fellowships in 2026 to establish your own research lab why not consider @sussex.ac.uk Life Sciences as your host.
Information, support and policy ππ
www.sussex.ac.uk/webteam/gate...
As 2025 draws to a close, and we sign off for the Xmas New Year break, with @sussexcancer.org we review another great year for the Sussex Blood Cancer Research Network.
With more exciting news to announce soon, hereβs to a pleasant and fruitful 2026 π₯
sussexcancer.org/news/sussex-...
Many thanks to all co-authors at @sussexbcr.bsky.social @bsmsmedschool.bsky.social @sussex.ac.uk @sussexcancer.org @biochembiomeduos.bsky.social and beyond who contributed to the study, funders for kindly supporting our work, and all our patients who selflessly donate samples for research.
πNetwork PhD Opportunity!π¬
New project in Dr Fabio Simoesβ group in @bsmsmedschool.bsky.social with Oct 2026 start examining the role of the bone marrow niche in AML disease biology.
3-year funding covering tuition fees (home rate) deadline Jan 30th 2026. Apply π
www.findaphd.com/phds/project...
π Network pre-print notification!π
New pre-print posted from @rhysmorganlab.bsky.social in @sussex.ac.uk led by Drs Hyun Park from @bsmsmedschool.bsky.social and Okan Sevim from @biochembiomeduos.bsky.social revealing a new regulator of leukaemia and stem cell growth; a deadenylase known as TOE1.
Fresh from presentation at @ash.hematology.org #ASH2025, pleased to present our latest pre-print showcasing the hard work of Drs Hyun Park & Okan Sevim. Exploration of b-cateninβs post-transcriptional role has revealed a novel AML cell and stem cell regulator; TOE1.
www.biorxiv.org/content/10.6...
Stellar job by our Drs Sevim and Goff from @sussex.ac.uk @sussexbcr.bsky.social @sussexcancer.org @biochembiomeduos.bsky.social for presenting their @cclguk.bsky.social LMRUK BSH Sussex Cancer Fund funded ASH achievement award research on the final night of @ash.hematology.org #ASH2025 in Orlandoπ
ποΈPublication update!ποΈ
Congrats @chrispepper68.bsky.social @bsmsmedschool.bsky.social for his new paper in @pubs.acs.org Jnl of MedChem with @mirazrahman.bsky.social at @kingscollegelondon.bsky.social on generating new efflux-resistant TKIs for CML treatment. π
pubs.acs.org/doi/10.1021/...
Well done to Drs Hyun Park and Aaron Goff from @biochembiomeduos.bsky.social @bsmsmedschool.bsky.social @sussexbcr.bsky.social whoβve both had abstracts accepted for presentation at the @ash.hematology.org 2025 meeting in December, and been awarded ASH achievement awards!
See you in Orlando! πΊπΈ
Tonight was the U.K. premier of βGoodbye Breastsβ written, directed and produced by Joanne Callaghan, documenting her remarkable breast cancer story. A must see!
@gdsc-sussex.bsky.social
@sussexcancer.org
@sussexbcr.bsky.social
sussexcancerfund.co.uk
Looking for a PhD on stem cells, microenvironment and gene regulation/alternative splicing. Join us for this great project with @whatchamacaulay.bsky.social
Prof. Tim Humphrey and Dr. Rhys Morgan both gave talks at the recent "Science CafΓ©" hosted by the Sussex Cancer Fund in partnership with the Macmillan Horizon Centre. A fabulous series of short talks for anyone interested in hearing a little more about the latest developments in cancer research.
πΎNew promotion in the network! π
A massive congratulations to Simon Mitchell @mitchell.science from @bsmsmedschool.bsky.social recently promoted to Professor!
Simon has transformed the Cancer Research portfolio at Sussex with his work at the Sussex BCR and the creation of @sussexcancer.org
πππ
Excited to have been promoted to Professor in Cancer Systems Biology at @bsmsmedschool.bsky.social, University of Sussex, @uniofbrighton.bsky.social
Many cancers begin as precancerous conditions. But what happens when these early cells coexist with a full-blown tumour?
Join us for an MRC funded PhD studentship exploring how primary cancers influence the evolution of precancerous cells.
www.findaphd.com/phds/project...
π°New funding updateπ°
Congratulations @rhysmorganlab.bsky.social in @biochembiomeduos.bsky.social for obtaining funding from @bloodcanceruk.bsky.social to target abnormal cell signalling mechanisms in AML.
This is now 1 of 6 active Blood Cancer UK grants in our growing network at Sussex. π π¬π§¬π₯Όπ©Έ
Very grateful to have been awarded our first @bloodcanceruk.bsky.social research grant over the summer for our work targeting aberrant Wnt/Ξ²-catenin signalling in acute myeloid leukaemia (AML).
Our new project headed by Dr Wagstaff begins Oct 1st developing new ways to target oncogenic Ξ²-catenin π
Delighted to wave the flag for @gdsc-sussex.bsky.social
@sussexcancer.org
@sussexbcr.bsky.social
sussexcancerfund.co.uk together with Rhys Morgan at the Science Cafe, MacMillan Horizon centre today. Thanks to Rebecca Herbertson and Stephen Robinson for organizing.
@rhysmorganlab.bsky.social
Our Co-Directors Prof @chrispepper68.bsky.social and Dr @rhysmorganlab.bsky.social explain the mission and vision for the Sussex Blood Cancer Research network.
@sussexcancer.org @bsmsmedschool.bsky.social @biochembiomeduos.bsky.social
π‘ How are #BSMS researchers working to change the future of blood cancer?
Prof Chris Pepper and Dr Rhys Morgan share their journey, their goals and why this research matters.
βΆWatch here: www.youtube.com/watch?v=0EwD...
@sussexbcr.bsky.social #MedicalResearch