Sophie Georgin-Lavialle

Kudos to Pauline, Flora, Yvan and the #Pyrin team, and many thanks to all the collaborators notably @sophiegeorgin.bsky.social @fhu-inflamme.bsky.social, Alessandra Carbone & Marco Gattorno's teams.

Thanks for highlighting our work!

Mapping the infectious burden in VEXAS syndrome: a systematic review and rationale for prevention

Valentine Ribier and colleagues characterise the infectious burden of VEXAS syndrome and propose preventive strategies bit.ly/3VDJIPq
@terrierben.bsky.social
@sophiegeorgin.bsky.social

Very happy to launch this project!

#WeekendRead! #MysterySolved! Saidoube @casanovalab.bsky.social Gillet @ahmad-yatim.bsky.social &co show @jem.org that excessive TLR7 activation in pDCs drives type I #Interferons protecting against SARS-CoV-2 but at the same time causing chilblains!
rupress.org/jem/article/...

Review: Spaan, Boisson, and @sethlucianmasters.bsky.social review the known primary disorders of the polyubiquitination pathways in humans that lead to #autoinflammation and/or #immunodeficiency rupress.org/jem/article/...

😃 J-6 avant la tenue de l’édition 2025 des MIPs

🗓️ Vendredi 18 avril 2025 à l’institut Imagine à Paris ! La journée sera accessible en présentiel et en distanciel.

👉 Prolongation des inscriptions jusqu’à lundi 14 avril 12h !
🛜 Lien d’inscription : www.eventbrite.com/e/mip-2025-t...

New Diseases Linked to MEFV Variants or Pyrinopathies Autoinflammatory diseases (AIDs) are characterized by dysregulation of innate immunity, leading to systemic inflammation. Familial Mediterranean fever (FMF) is the most common AID, associated with var...

& pyrin-associated autoinflammation with hypereosinophilia. A section dedicated to current somatic forms of FMF is also developed. Several patients with undifferentiated systemic AIDs/syndrome of undifferentiated recurrent fever

www.jaci-inpractice.org/article/S221...
@jaciinpractice.bsky.social

New Diseases Linked to MEFV Variants or Pyrinopathies Autoinflammatory diseases (AIDs) are characterized by dysregulation of innate immunity, leading to systemic inflammation. Familial Mediterranean fever (FMF) is the most common AID, associated with var...

This review provides an update on AIDs associated with pathogenic variants in MEFV ( #pyrinopathies ). Those include new dominant forms (exon 10 delM694 & non-exon 10 T577, H478, P373), pyrin-associated autoinflammation - neutrophilic dermatosis, pyrin-associated autoinflammation- neuroinflammation

New Diseases Linked to MEFV Variants or Pyrinopathies Autoinflammatory diseases (AIDs) are characterized by dysregulation of innate immunity, leading to systemic inflammation. Familial Mediterranean fever (FMF) is the most common AID, associated with var...

#Medsky🧪 #Immunosky #Autoinflammatorydiseases (AIDs) are characterized by dysregulation of #innateimmunity, leading to systemic inflammation. Familial Mediterranean fever (FMF) is the most common AID, associated with variants in exon 10 of MEFV

Thank you for highlighting our review on pyrin associated diseases!

Thank you Alexandru gor highlighting our work !

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)? A new study shows that some of our cells favor genes of one parent or the other and can explain a longstanding mystery of why some people with disease-causing genes experience no symptoms.

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)?
Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼