I am not very active lately in social media, but if you want to see one of our latest works check Alberto’s post on the fitness cost of AMR genes. Great delivery from him and all collaborators. Thanks, guys!
bsky.app/profile/albe...
Great work led by MBAlab @jaescudero.bsky.social with the invaluable collaboration of @sanmillan.bsky.social @baerboletta.bsky.social @penamiller.bsky.social and @ayari.bsky.social
Excited to share our latest work! 📝
We measured the fitness effect of 136 AMR genes and found that many are neutral or even beneficial without selection. 🤯🧬
Oxygen availability can flip their fitness and our stochastic model indicates that oxygen fluctuations help maintain them.
Learn more 👇🏼
👏 Dos proyectos del #CNB seleccionados en la convocatoria de Investigación en Salud 2025 de la @caixaresearch.bsky.social
Ambos abordan un gran reto global: la resistencia a los antimicrobianos.
#HealthResearch #FundaciónlaCaixa
@sanmillan.bsky.social @jaescudero.bsky.social
f.mtr.cool/jejatlbssz
Can I be included? Pleaaaaaaseeeeee!
New preprint out! 📣🚨
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Excited to share my latest review, now published in the Royal Society theme issue on ‘The ecology and evolution of bacterial immune systems' (available OA):
Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae royalsocietypublishing.org/doi/10.1098/...
A pleasure to read, as all Andreas Wagner’s books. They always shake some of the pillars that support my view of things.
I highly recommend reading all of them, especially to young scientists. In Sleeping beauties I particularly enjoyed the mix with neuropsychology.
El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis.
https://f.mtr.cool/rnstpoiucs
El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis.
https://f.mtr.cool/czgfpzevqu
Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects? 🦠 =>processes evolutionarily tuned to be sensitive to translation speed eg: motility, iron homeostasis, leader peptide attenuation (ex: trp). #rnasky #microsky www.sciencedirect.com/science/arti...
Oxygen levels can affect how resistance genes work, impacting antibiotic efficacy. This can be relevant for the most used ones: for example, resistance to fosfomycin varies with oxygen.
Learn more in our latest paper 👉 bit.ly/3T8sdpp a work led by @jaescudero.bsky.social
#AntibioticResistance
A 2 yr postdoc position at the Bacterial
Genome Plasticity Unit of the Institut Pasteur (Paris) led by @amazeld.bsky.social in collaboration with Pierre-Alexandre Kaminski, funded by the French National Research Agency 👇
🚨🚨 New paper in @narjournal.bsky.social! 🍾
Excludons are pairs of overlapping genes that block each other’s expression (basically, reverse operons).
We built a tool to identify them in bacterial genomes using transcriptomic data, in an awesome collab led by Iñigo Lasa and Álvaro San Martín.
👇
Congrats Carlos!! Very nice!!!
When the MSc student of Enea @phagemuffin.bsky.social is working in a brewery... 🍺🧬
A gym that you go to but instead of working out you write papers
Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬?
In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments!
👇 Check out all the details in Paula’s thread!
Hint: 🐇 (most of the time)
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!
We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome.
See thread for more information and reach out!
Enjoy! It is indeed an amazing place!
A #short about mirror bacteria in French with subtitles, except for me, by @leblob.bsky.social
youtube.com/shorts/i0N55...
This Craig Maclean guy looks like he’s going places, one to keep an eye on! 👀
Congrats! 🎉
At 43: having money.
At 45: publishing a first author paper
At 60: having sex.
At 70: having a drivers license.
At 75: having friends.
At 80: not wetting your pants.
I guess we will have to add a couple of lines to the joke on success:
At age 4 success is not wetting your pants.
At 12: having friends.
At 16: having a drivers license.
At 20: having sex.
At 23: publishing a 1st author paper
At 28: having money.
New paper with @rwheatley8.bsky.social and Cedric Lood
Actual title: Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy.
Sensationalist title: Plasmids carry useless genes
academic.oup.com/ismej/articl...
People from the lab killing it
At the Duomo with friends
Super proud of the lab for their outstanding presentations at #FEMS2025 in Milano!
Science is better when you work with such a stellar team!🚀✨
@femsmicro.org
