I see a pattern here…
18.12.2025 13:43
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I see a pattern here…
#RenalPath: Diffuse granular capillary wall staining for phospholipase A2 receptor (PLA2R). PLA2R staining is positive in approximately 70% of patients with clinically idiopathic membranous nephropathy (immunofluorescence microscopy, PLA2R).
bit.ly/2xVkJzs (FREE)
Tell me you are shooting yourself on the foot without telling me you are shooting yourself on the foot.
Heard that Twitter is imploding. Good riddance
Thanks. I wish it was more accessible. @maximalchange.bsky.social any chance you can share?
@hswapnil.medsky.social @kidneyboy.bsky.social
What’s the name of the nephrology song you play at the end of the podcast?
Outstanding
The second sibeprenlimab paper in @nejm.org
(At least we gave it an oral at #KidneyWk unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
Maybe because not all attendees are expert nephrologists? Lots of students, residentes, nurses attending as well.
And it’s live
Iptacopan in C3GN makes it to @thelancet.com
www.thelancet.com/journals/lan...
#NephSky
Awesome congrats!!! Is this limited to losartan or it would be more a class effect of ARBs?
Amazing to me that a seemingly acute event is either
A) has long-term sequellae despite being apparently resolving or
B) a dramatic and early presentation of profound endothelial disease
Amazing reference
Way scarier story. Stories.
www.nytimes.com/2025/06/13/t...
(Gift link)
Sibeprenlimab in IgA Nephropathy #ERA25
* Data presented is the 9-month reduction in proteinuria
Dr Meghan Sise presenting on serum cr/cystatin outcomes in patients treated with cisplatin or carboplatin
#Onconeph #ERA25
Shite!
Adverse effects
Hyperkalemia rates not lower with adding a flozin to the MRA 🤔
www.nejm.org/doi/full/10....
#ERA25
Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.
The first #ERA25 simultaneous pub
CONFIDENCE trial of empagliflozin + finerenone in N = 579
Greater reduction in ACR and BP
Note the impressive GFR dip
www.nejm.org/doi/full/10....
A graph of the least-squares mean ratio of the change from baseline in the urinary albumin-to-creatinine ratio in the full analysis population.
In the CONFIDENCE trial in persons with chronic kidney disease and type 2 diabetes, combination therapy with finerenone and empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either drug alone. Full trial results: nej.md/4jEVbbk
#ERA25 #MedSky #Nephrology
Missed it. Give us the highlights! #ERA25
@kevinyau.bsky.social GLP1 agonist master Jedi presenting at #ERA25.
💉GLP1 agonist reduce ED visits and hospitalizations!!!
📉Awesome methods. Best of the session:
💊DDP4 for comparison, IPTW, ICES data. Ticking all the right boxes (EPI nerd).
💊Only 40% on SGLT2i!!! We should flozinate more!!!
@kevinyau.bsky.social @armelleid.bsky.social
I wish we had any of the new treatments in Canada. Any.
#ERA25 baby!!!
Visual abstract
Experiential Evidence of Systemic Racism for Indigenous Peoples Navigating Transplantation in Canada - in @kireports.bsky.social
www.kireports.org/article/S246...
#NephSky
The US spends billions of dollars on binders every year
We are doing the RCT to get you the answer - more than 3000 enrolled
ajkdblog.org/2021/06/16/c... and www.nephjc.com/news/2021/2/...
I am not going. But see you in Vienna!!!!
I feel you pain bro.
Read the same in Brener’s book long time ago