Zach Hopkins, MD

The goal is to provide an avenue for patients with challenging skin conditions to both track their symptoms, flared, and medications on a single platform and have that platform sync with their physician so issues can be proactively identified and the the data can be used in the visit

David Geier has apparently been commissioned by HHS secretary RFK, Jr. to study potential links between vaccination and autism.

He and his father have 2 papers in 2017/2016 claiming to show Hep-B vaccination greatly increases risk of autism/obesity.

However, their studies have FATAL FLAW...

The general vibe we are getting across #NIH institutes is deeply bleak — that the agency is nearly, if not already dead.

Top people are leaving or have left. Nearly everyone's looking for other jobs. People still care about what NIH was, but are growing resigned to its death.

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The Trump Administration Goes To War With Health-Care Quality Inside its plan to destroy a small agency that keeps you safe.

The administration is working on demolishing AHRQ, the agency whose mission is to improve healthcare quality and safety.

www.offmessage.net/p/the-trump-...

Images in Clinical Medicine Linear IgA Bullous Dermatosis of Childhood Panel A: Tense vesicles and edematous pink plaques with central erosions and crust on the patient’s legs. Panel B: Direct immunofluorescence revealing a linear band of IgA along the dermoepidermal junction.

A 2-year-old boy presented with a 1-week history of itchy, red spots. Tense vesicles, erosions, and inflammatory plaques were seen. Direct immunofluorescence revealed a linear band of IgA at the dermoepidermal junction. Read the full case details: nej.md/3R6CIIA

#MedSky #DermSky #PedSky

Important concern that PRS in their current form risk exacerbating current disparities in medicine Non-European training data is limited ... (Figure shows almost all generic data related to cardiovascular disease comes from those of European descent) ... Leading to reduced PRS performance in Non-Europeans (Figure shows polygenic risk scores perform worse among those with East Asian and African ancestry)

When the data on which we make guidelines and recommendations comes almost exclusively from one ancestry group (in this case, white folks of European ancestry), the recommendations will be less effective for those from other backgrounds. That’s part of why health equity matters.

Research coordinator, a young woman with face barely visible thru a biohazard bag, holds up two purple tubes full of my blood

Doing a test run for my NIH grant pilot trial today: I donated a bit of blood and the research coordinators are finalizing the blood processing workflow

This is a study of vitamin supplementation for knee osteoarthritis

Upadacitinib isn’t a biologic though…😜

I received this reply from @davemccormick.bsky.social re: #NIH indirects. I am still waiting to hear from @fetterman.senate.gov. #NIH funding is a key economic driver and is responsible for the cures & miracles I see in my clinic every day. Contact your reps at @5calls.org
#DermSky #SciSky #MedSky

Thank you! 😀

#dermatology #dermfoundation #dermsky

Excited to announce that my @dermatologyfoundation public health career development proposal was accepted "Development of a patient-reported outcome-based autoimmune skin disease monitoring program." This proposal centers on innovative applications of patient-reported outcomes for disease monitoring

Rituximab shows long-term efficacy in Pemphigus Foliaceus & Vulgaris patients. Exciting data from a cohort study! #Dermatology PMID:40042819, JAMA Dermatol 2025 https://doi.org/10.1001/jamadermatol.2024.6654 #Medsky 🧪

Subdermal implants vs. levonorgestrel intrauterine devices outcomes in reproductive-aged women: a systematic review and meta-analysis - PubMed PROSPERO ID: CRD42024516472.

Some more evidence from a meta-analysis of 6 RCTs to support that subdermal implants (i.e. Nexplanon) are more likely to cause acne than hormonal IUDs (OR 2.21). Something to keep in mind for those concerned about acne who otherwise don't have strong preferences.
pubmed.ncbi.nlm.nih.gov/40069520/

For better or for worse (worse), MEASLES are back, so here's a #skytorial on recognizing this once thought eradicated disease.

MEASLES: a tutorial!

#dermsky #medsky #MedEd
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NIH reels with fear, uncertainty about future of scientific research The Trump administration’s orders have created more turmoil and damage at the National Institutes of Health than was previously known.

If you want a deep dive on what is going on at #NIH read this @washingtonpost.com article
#MedSky #SciSky #DermSky #EpiSky

www.washingtonpost.com/science/2025...

Figures showing the change from baseline to week 1 (post hoc analysis), week 12 (primary end point), and week 24 (exploratory analysis) in the weekly urticaria activity score (i.e., the score during a 7-day period) among patients who received either remibrutinib at a dose of 25 mg twice daily or placebo in the REMIX-1 trial (Panel A) and in the REMIX-2 trial (Panel B).

In two trials involving patients with chronic spontaneous urticaria, remibrutinib led to significantly greater reductions than placebo in itching and hives at week 12. Full results of the REMIX-1 and REMIX-2 trials: nej.md/41uQD07

#MedSky #DermSky