This study shows that DNA-mismatch-repair-deficient cell populations maintain high growth rates despite a high SNV burden of at least 50,000 mutations per cell. In these cells, the INDEL burden plateaus at approximately 16,000 per cell.
doi.org/10.1016/j.xi...
#SomaticMutations #CellularAging
29.08.2025 04:43
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This review discusses the application, challenges, and future development directions of artificial intelligence in various branches of life sciences, including zoology, plant science, microbiology, biochemistry......
doi.org/10.59717/j.x...
#lifesciences #artificialintelligence #research
01.09.2025 05:17
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This review underscores the importance of a multifaceted approach to obesity management, aiming to curb the escalating trend and enhance future interventions and treatments. Read more
doi.org/10.59717/j.x...
#medicine #obesity #healthylifestyle
01.09.2025 05:22
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This review explores the opportunities and challenges posed by AI in modern medicine, highlighting its applications in precision healthcare, phenomics, early diagnostics, and personalized treatment. Read more
doi.org/10.59717/j.x...
#medicine #artificialintelligence #healthcare #research
01.09.2025 05:25
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In this review, Xiao et al. discuss recent advancements in our understanding of DC biology under homeostatic conditions and within the tumor microenvironment with a particular emphasis on insights gained through single-cell multi-omics.
doi.org/10.59717/j.x...
#Medicine #DendriticCells #research
30.04.2025 04:37
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This perspective summarizes the characteristics of altered follicular fluid iron content and oocyte quality in EMs-associated infertility patients, along with detection methods and correlative studies. Read more
doi.org/10.59717/j.x...
#medicine #research #ReproductiveHealth
04.05.2025 04:37
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In this review, Zhai et al. introduce the conditions of the gut microbiome in COVID-19 and how it gradually develops in PCS patients, and its possible mechanisms influencing the main symptoms of PCS patients. Read more
doi.org/10.59717/j.x...
#medicine #microbiome #postcovid
08.05.2025 03:19
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Li et al. describe the common molecular mechanisms or organelles of exosome biogenesis and autophagy in cells, as well as the potential implications of exosomes regulating autophagy in diseases after internalization by target cells.
doi.org/10.59717/j.x...
#lifesciences #exosome #research #TIC2025
10.05.2025 04:52
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This review will introduce the common types of sports injuries, traditional clinical strategies and explore the current application status of regenerative medicine in sports injuries. Read more
doi.org/10.59717/j.x...
#medicine #sportsinjury #research
13.05.2025 03:45
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Great News! On May 15, 2024, The Innovation Life (ISSN: 2959-8761) was officially indexed by the Scopus database!
We extend our sincere gratitude to our dedicated authors, reviewers, editors, and incredible readers for their invaluable contributions and unwavering support.
#news #Science #research
16.05.2025 03:05
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This commentary delves into the nuances the DO-HEALTH trial's findings and their broader implications for aging research and public health. Read more
doi.org/10.59717/j.x...
#Medicine #aging #PublicHealth #TIC2025
16.05.2025 03:13
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Check out the latest issue of The Innovation Medicine!!!
Volume 3, Issue 1 is now online!
www.the-innovation.org/medicine/art...
#medicine #research #Clinicaltrial #obesity #Lupus #CART #artificalintelligence #diabetes #vaccines #epigenetics #EHR #diseases #inflammation #antifungal #LungCancer
27.02.2025 03:20
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In this Perspective, Zhou et al. briefly introduce the general concepts of AI and organoids/OoCs, explore their state-of-the-art applications in DDD, and discuss why and how their synergistic impacts can revolutionize the R & D of new drugs.
doi.org/10.59717/j.x...
#lifesciences #AI #Research
24.02.2025 04:33
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Check out the latest issue of The Innovation Life!!!
Volume 3, Issue 1 is now online!
www.the-innovation.org/life/article...
#lifesciences #circulation #molecularbiology #microbiome #genetics #epigenetics #genomics #technology #Bioinformatics #organoid #Research
24.02.2025 04:41
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This study demonstrates that ZSH-512 effectively inhibits CSC-mediated tumorigenesis and metastasis through its epigenetically modulating stemness pathways, primarily via the RARΞ³-KDM3A axis. Read more
doi.org/10.1016/j.xi...
#medicine #research #CancerResearch
28.02.2025 05:03
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By examining the entire process of multimodal information fusion, we can gain deeper insights into AIβs working mechanisms and enhance our understanding of AI perception in complex environments. Read more
doi.org/10.1016/j.xi...
#ArtificialInteligence #research
01.03.2025 03:18
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In the near future, the application of single-atom catalysts is expected to extend to other photoelectrodes , further boosting the practical application of photoelectrochemical water splitting systems. Read more
doi.org/10.1016/j.xi...
#catalyst #research
01.03.2025 03:30
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Xu et al. commented on a recent study that explored the formation and retention mechanisms of epigenetic obesity memory at the gene expression level, offering systematic and comprehensive insights into the #epigenetic mechanisms underlying #obesity and weight cycling.
doi.org/10.59717/j.x...
22.02.2025 04:50
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By leveraging advanced technologies, fostering interdisciplinary collaboration, adhering to the highest standards of evidence generation, traditional Chinese #medicine could transition from a traditional practice to a scientifically validated discipline.
doi.org/10.59717/j.x...
#Research #Clinical
22.02.2025 05:00
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He et al. introduced chimeric antigen receptor (CAR) T-cell therapy for #pediatric patients with refractory systemic lupus erythematosus, demonstrating promising #clinical outcomes and significant societal impact.
doi.org/10.59717/j.x...
#medicine #systemiclupuserythematosus #Research
22.02.2025 05:16
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Wang et al. summarize the strategies and limitations of current drug development methods and explore innovative approaches for creating effective antifungal therapies. Read more
doi.org/10.59717/j.x...
#Medicine #research #antifungal
23.02.2025 05:51
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This study pioneers a multi-stage deep learning model for pediatric tooth segmentation, classification, and treatment planning, with a focus on predicting tooth germ staging. Read more
doi.org/10.59717/j.x...
#Medicine #research #ArtificialIntelligence #pediatric
23.02.2025 05:57
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Sun et al. commented on a recent study that introduced an oriented monolayer polyhedral (OMP) membrane with a high-density arrangement of MOF particles, optimized for separating aromatic and aliphatic hydrocarbons in naphtha. Read more
doi.org/10.59717/j.x...
#MaterialsScience #AdvancedMaterials
23.02.2025 06:14
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No matter what the future of room temperature superconductors (RTS), the pursuing for RTS requires the spirit of exploration, endeavor and curiosity in science, it will certainly change our world and knowledge forever. Read more
doi.org/10.59717/j.x...
#materials #superconductors #technology
23.02.2025 06:21
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This study shows that higher glycogen deposition occurs in the liver but not in the muscle on GD 60 in low-body-weight fetuses. Abnormal deposition of glucose in the liver, which is required for fetal development at mid-gestation, may lead to retarded fetal growth.
doi.org/10.59717/j.x...
#research
23.02.2025 06:28
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In this study, Ni et al. investigated bacterial and methanogenic community composition and methanogenic metabolic pathways in the shallow, middle, and deep depths within a 2-km profile of Quaternary saline lacustrine source rocks in the Qaidam Basin using metagenomic analysis
doi.org/10.59717/j.x...
21.02.2025 03:59
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Research on Human metapneumovirus infection remains limited. While progress in vaccine development is promising, further advancements in this field will be crucial for preventing and controlling major respiratory #virus infections.
doi.org/10.59717/j.x...
#Medicine #vaccine #disease
20.02.2025 04:27
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This study reveals that RA not only increases the odds ratio of neuropsychiatric disorders but also impacts gray matter volume and brain activity. These findings underscore the importance of vigilant monitoring of the neuropsychiatric system in RA patients
doi.org/10.59717/j.x...
#Medicine #research
20.02.2025 04:32
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This review provides a systematic overview of the development understanding of BALF, discusses its possible applications in clinical diagnosis, prediction, and intervention, and highlights the role of emerging omics technologies in deciphering BALF.
doi.org/10.59717/j.x...
#Medicine #research
20.02.2025 04:36
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