Lipid Droplet Targeting Drives Substrate Access during Very Long Chain Fatty Acid Activation by Fat1 https://www.biorxiv.org/content/10.64898/2026.02.09.704383v1

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social.
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

Hey there!✨I’m thrilled to share that our latest research, in collaboration with the Tontonoz Lab (UCLA), has just been published in Nature Metabolism. Our study explores the fascinating role of polyunsaturated fatty acids in fat storage. Check it out!
@labvanni.bsky.social
@natmetabolism.nature.com

Happy to share some glimpses of my recent PhD dissertation defense✨🎓📜
@unifr.bsky.social @unifrbiology.bsky.social
#computationalbiophysics #moleculardynamics #biochemistry

We are hiring!🎇💣 if you are looking for a position as PhD student or Postdoctoral researcher in the field of computational biophysics, apply via email!

lnkd.in/ex7CseJP

Dietary control of peripheral adipose storage capacity through membrane lipid remodelling Complex genetic and dietary cues contribute to the development of obesity, but how these are integrated on a molecular level is incompletely understood. Here, we show that PPARγ supports hypertrophic ...

Jennifer also contributed to this amazing tour-de-force on the characterization of LPCAT3 and the role of polyunsaturated lipids in white adipose tissue. Congratulations to first authors Marcus Tol and Yuta Shimanaka from the Tontonoz lab! (3/3)
www.biorxiv.org/content/10.1...

An S-acylated N-terminus and a conserved loop regulate the activity of the ABHD17 deacylase ABHD17 enzymes remove fatty acids from membrane proteins like NRas. This study shows that their activity depends on two mobile regions: an S-acylated N-ter

The work of “soon-to-be” (we will miss her!) graduate Jennifer Sapia on the S-acylase ABHD17 (in collaboration with the lab of @lizconibear.bsky.social and grad student Sydney Holme) is also out! (1/3)
buff.ly/4b3E0xy