Belated 🎓Congratulations 🎓to Dr Tiffany Kung, @tiffkung.bsky.social who successfully defended their PhD thesis "Anti-Edema Therapies and Sex Hormones after Experimental Stroke." Tiffany is co-supervised by Fred Colbourne and Ana Klahr.
Way to go Dr Kung!
A huge thank you to my co-authors who helped me put this together: Angely Suerte, Elmira Khiabani, Marin Parranto, Sara Gannon Arnott, @akalisva.bsky.social, @itchyshin.bsky.social, my supervisors Ana Klahr and Fred Colbourne, and CIHR for funding this work!
Finally, we stuck to rigorous and robust techniques to reduce Type I error in our results, including:
⭐ Hierarchical meta-analysis and robust variance estimation
⭐ Article pre-registration with #PROSPERO
⭐ Open data sharing on OSF (osf.io/kf7t2/overview)
Perhaps unsurprisingly, sex and gonadal status were significant moderators of estrogen and progesterone's effects, which with further study may provide insight into how menopausal #HRT, #birthcontrol, and #GAHT may affect stroke outcomes
Key findings:
🧠 Estrogen and progesterone seem to improve outcomes after AIS
🧠 Limited data on testosterone is available, but preliminary analysis suggests lower doses may be more beneficial and higher doses may be harmful
🧠 More research is needed in ICH and SAH!
So excited to announce my most recent project is now in press!
Our meta-analysis looks at the effects of exogenous #estrogen, #progesterone, and #testosterone in pre-clinical models for 3 subtypes of #stroke: AIS, ICH, and SAH.
Catch it at Biology of Sex Differences here:
doi.org/10.1186/s132...
Oh my gosh that looks amazing!! Haha I love it!
What an awesome idea!! That is unfortunately not on my normal bike route, but I'll have to swing by there sometime to meet some of the other biking folks in town :) (though I'm only a summer biker haha)
📚 Prevalence of Transparent Research Practices in Psychology: A Cross-Sectional Study of Empirical Articles Published in 2022
journals.sagepub.com/doi/10.1177/...
Henrietta Swan Leavitt, age 30 (July 4, 1868 – December 12, 1921) Public Domain Author: unknown
1/n #WomenInSTEM 🔭🧪⚛️
12 December 1921: Henrietta Swan Leavitt, a great pioneer of modern astronomy, passed away.
Her name is not familiar to most people and she is certainly not as recognizable as Galileo, W. Herschel, or E. Hubble, even though it ought to be.⤵️
The AI madness is so far out of control that "Our product wrote a completely false news alert and credited a real news source" doesn't even rate a corporate comment, let alone an ashamed apology and pulling the product www.bbc.com/news/article...
This is how science should work. 💡
I participated in a faculty panel a few weeks ago in which senior (ahem) faculty gave advice on careers in academia by pretending luck had very little to do with our success. One piece of advice riled me up, in which it was argued that a reason for their success was their ability to say no. 1/
“The fact that she keeps up the work and still pushes on paper mills in Russia is a testament to who she is.”
Congratulations to our partner @abalkina.bsky.social on this well-deserved honor from Nature.
www.nature.com/articles/d41...
#EvidenceSynthesis #SystematicReviews
Personally, I'm pretty passionate about my puppy (who loves me I swear) and also playing tons of video games in my spare time 🎮!
I guess I should introduce myself here? Hello 👋 I'm Tiffany and I'm a PhD candidate at the University of Alberta! Professionally, I'm passionate about translational science and literature synthesis in the field of stroke.
If you had to cite an event that opened the "replication crisis" era, what would you point to?
Here is a cool little function for R that lets you check if all of the loaded packages are actually necessary for the code that follows, letting you cut down on unneeded packages. Really helpful for grading student code too, since this is a common error!
funchir::stale_package_check('mycode.R')
There are many layers here, but I want to comment on one aspect of these findings for now--the editorial board representation. Some will see this and immediately think: we need to get more POC on our boards! I understand that impulse, but encourage you to think a few steps down the game tree 1/n.
