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Sarah Moyon

@neurosarah

Neuroscientist @inp-marseille.bsky.social, Myelin & OPC enthusiast with an Aging twist, Chaire d’Excellence #Amidex #AMU, moyonlab.com, She/her

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15.11.2024
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Latest posts by Sarah Moyon @neurosarah

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Le French Glial Cell Club participe à la Semaine du Cerveau avec France Alzheimer !

📅 Rendez-vous en ligne pour un live immersif
🕘 Lundi 16 mars à 19 h
📍 Sur YouTube et Twitch

Découvrez les avancées de la recherche, le rôle central des cellules gliales et posez vos questions à nos experts.

26.02.2026 09:15 👍 5 🔁 4 💬 0 📌 0
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Marseille folks: I’m organizing a one-day workshop on Distributed Computations for Flexible Behavior (Apr 16, Timone Campus) with a great line-up of speakers bridging theory, circuits & whole-brain dynamics! 🧠

Free registration (mandatory, incl. lunch): fannycazettes.limesurvey.net/172448?lang=...

17.02.2026 08:47 👍 24 🔁 11 💬 0 📌 0
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GLIA 2027 (7–10 Jul, Bologna) introduces Technical Symposia! Showcase cutting-edge methods & tools in glial research. Industry partners welcome. Submit by 8 Apr 2026.
🔗 https://www.glia-meeting.eu/2027/call-for-symposia/

#GLIA2027 #Neuroscience #GlialResearch #Innovation

12.02.2026 03:20 👍 6 🔁 5 💬 0 📌 1
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CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity CDC42-effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin-dependent scaffolding of myelin. Myelin o...

If you're interested in the factors that enable the regular structure of CNS #myelin sheaths by #oligodendrocytes, check this out. Featuring a #CDC42 - effector proteins - #septin axis. Congrats to 1st author Sophie, and a big thank you to all who contributed

onlinelibrary.wiley.com/doi/10.1002/...

02.02.2026 09:40 👍 12 🔁 6 💬 0 📌 0
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Myelin is repaired by constitutive differentiation of oligodendrocyte progenitors Oligodendrocytes form myelin sheaths around axons to enable rapid signaling within neural circuits. The generation of new oligodendrocytes through differentiation of oligodendrocyte precursor cells (O...

alert! fundamental myelin biology - led by the amazing Yevgeniya Mironova and Dwight Bergles www.science.org/doi/10.1126/...

23.01.2026 02:48 👍 17 🔁 6 💬 0 📌 0
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Direct labeling of microtubule turnover reveals in-lattice repair and stabilization patterns in developing neurons The microtubule cytoskeleton is the backbone of neuronal morphogenesis, driving the development of the dendrites and axon, and supporting trafficking to distant compartments. How neuronal microtubules...

🚨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 🧵 1/9

12.01.2026 19:14 👍 102 🔁 31 💬 4 📌 2
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Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination Cuprizone demyelination induces transient reactive states in deep cortical microglia (MG) through early recovery. Depleting MG in recovery increases the number of deep cortical mature/pre-myelina...

Our Paper is out! We studied cortical microglia and regenerating oligodendrocyte (OL) interactions. In short: demyelination induces transiently reactive microglia and depletion of these reactive microglia increase recovering OL number onlinelibrary.wiley.com/doi/10.1002/...

09.01.2026 14:09 👍 24 🔁 5 💬 2 📌 0
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En 2023, le montant du crédit d’impôt recherche s’élève à 7,8 Md€ (données... "Au regard de leur exercice comptable de 2023, 29 720 sociétés déclarent 27 Md€ de dépenses éligibles au CIR, […] générant un crédit d’impôt de 7,8 Md€...

Le crédit impôt recherche aura couté 7,8 Md€ en 2023, soit presque 2 fois le budget du CNRS (4,1 Md€).

De l’argent donné à des multinationales sans aucun vrai contrôle de la recherche scientifique effectuée.

www.aefinfo.fr/depeche/7427...

05.01.2026 08:08 👍 109 🔁 81 💬 8 📌 7
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Mark your calendars! GLIA 2027 Call for Symposia opens 20 Jan–8 Apr 2026. All career stages & countries welcome. Accepted speakers get registration waived. More info: https://www.glia-meeting.eu/2027/call-for-symposia/
#Glia #Astrocytes #Microglia #Oligodendrocytes #NG2 #SchwannCells #StemCells

16.12.2025 02:48 👍 1 🔁 5 💬 0 📌 0

🙏 Thank you for all your help during this long application process @tepavcevicvanja.bsky.social

11.12.2025 11:04 👍 1 🔁 0 💬 0 📌 0
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Neuronal fatty acid oxidation fuels memory after intensive learning in Drosophila - Nature Metabolism Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy ...

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation.

Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

10.12.2025 11:13 👍 105 🔁 26 💬 4 📌 2

Super exciting news for the #OligOld team 🤩😱: our project Epiglia has been awarded an #ERCCog!
Ready to dive into the epigenetics of oligodendroglial cells in Alzheimer for the next 5 years with our amazing group and collaborators @inp-marseille.bsky.social @univ-amu.fr

09.12.2025 17:45 👍 21 🔁 3 💬 4 📌 1

Thank you!!

09.12.2025 17:40 👍 1 🔁 0 💬 0 📌 0
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Save the date!
NeuroPSI–TCCI Meeting on #Brain #Ageing & #Neurodegeneration
📅 28–29 May 2026
📍 Paris-Saclay / NeuroPSI + online

Join us to explore imaging, biomarkers, omics & AI to better understand and protect the ageing brain.
Registration & call for posters coming soon.

26.11.2025 14:56 👍 3 🔁 1 💬 0 📌 0
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The Transmitter’s Rising Stars of Neuroscience 2025 We recognize the outstanding achievements of 25 neuroscientists who stand to shape the field for years to come.

Thank you The Transmitter (@thetransmitter.bsky.social) for naming me a Rising Star of Neuroscience!

www.thetransmitter.org/early-career...

I wish I were at SfN to celebrate tonight with all the other awardees at the Simons Foundation's social.

17.11.2025 10:58 👍 10 🔁 2 💬 0 📌 0
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Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes INTRODUCTION The ε4 allele of the apolipoprotein E (APOE) gene is a risk factor for the development of Alzheimer's disease (AD). APOE4 isoform is associated with increased white matter lesions in hu.....

Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes - Al‐Amin - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

11.11.2025 04:37 👍 6 🔁 4 💬 1 📌 0

Interesting study from the ppl @solvingforsci.bsky.social. Very much in line with our earlier findings with @preprintclub.bsky.social (www.biorxiv.org/content/10.1...) :
1/ Reviewers can distinguish quality and impact (+novelty in our model)
2/ Trainees want to review
3/ Authors love the experience

11.11.2025 16:39 👍 2 🔁 1 💬 0 📌 0

🤩

04.11.2025 21:38 👍 1 🔁 0 💬 0 📌 0
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A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...

Link to new study in Science:

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.

🧪🧬
www.science.org/doi/10.1126/...

12.10.2025 07:37 👍 8 🔁 1 💬 1 📌 0
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Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation - Nature Communications Non-steroidal anti-inflammatory drugs (NSAIDs) are known to alleviate pain by reducing inflammation. To the contrary, here, the authors show that selective inhibition of the prostaglandin E2 receptor (EP2) in Schwann cells eliminates pain without disrupting the protective and healing functions of inflammation.

NSAIDs are known to alleviate pain by reducing inflammation. A study in Nature Communications shows that selective inhibition of the prostaglandin E2 receptor in Schwann cells eliminates pain without disrupting the protective and healing functions of inflammation. #medsky 🧪

13.10.2025 01:03 👍 60 🔁 22 💬 0 📌 1
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Daycare at Glial Cell Club next meeting (November 17-20, 2026) The GCC organizing committee is committed to supporting our community by helping reconcile professional and personal lives, especially for parents of young children. We are therefore working to provid...

The GCC is planning on-site childcare for the upcoming Glial Cell Club meeting (Nov 17–20, 2026, Lazaret site).
Please fill out our short survey to help us secure support and organize the service: forms.gle/GyLXfS6fhnVs...

Input is welcome even if you won’t use childcare.

30.09.2025 11:27 👍 5 🔁 3 💬 0 📌 0
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Matinée NeuroMAP – Visite de laboratoire | NeuroMarseille

NeuroMAP @neuromarseille.bsky.social @univ-amu.fr organise une visite de laboratoire sur le campus de la Timone le 14 Novembre ! Venez rencontrer nos chercheurs 👩🏻‍🔬🧑🏽‍🔬

neuro-marseille.org/events/journ...

01.10.2025 09:49 👍 3 🔁 2 💬 0 📌 0
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Facial expressions in mice reveal latent cognitive variables and their neural correlates Nature Neuroscience - The face reveals more than just emotion. Cazettes, Reato and colleagues show that subtle facial movements reveal hidden cognitive states, reflecting the brain’s ongoing...

Did you know that facial expressions reveal more than meets the eye? 🤯

Our new study shows that even a mouse's face 🐭 can reflect hidden neural computations🧠. Turns out, facial expressions are more than just emotions!

We're so excited to see this paper out @natneuro.nature.com 🎉
🔗: rdcu.be/eIQzO

30.09.2025 11:30 👍 67 🔁 16 💬 2 📌 1
Scientific productivity gap based on English-language peer-reviewed papers. Shown are the maximum % differences in the number of peer-reviewed papers published by female native English speakers from a high-income country (-45%), female non-native English speakers from a high-income country (-60%), and female non-native English speakers from a lower-middle income country (-70%), compared to male native English speakers from a high-income country (red flag). Credit: Tatsuya Amano

Scientific productivity gap based on English-language peer-reviewed papers. Shown are the maximum % differences in the number of peer-reviewed papers published by female native English speakers from a high-income country (-45%), female non-native English speakers from a high-income country (-60%), and female non-native English speakers from a lower-middle income country (-70%), compared to male native English speakers from a high-income country (red flag). Credit: Tatsuya Amano

How do your #linguistic, #economic & #gender backgrounds impact your #scientific productivity? @tatsuya-amano.bsky.social & co reveal that being a woman, a non-native English speaker, and from a low-income country is associated with a 70% reduction in productivity @plosbiology.org 🧪 plos.io/4n3RLRQ

19.09.2025 13:12 👍 20 🔁 11 💬 0 📌 4
Portail Emploi CNRS - Offre d'emploi - Post-doctoral researcher in axon biology (M/F)

✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir!

👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches.

Apply at: emploi.cnrs.fr/Offres/CDD/U...

Thank you for sharing! 👋 🙏

11.09.2025 12:24 👍 13 🔁 10 💬 0 📌 2
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Trump Is Shutting Down the War On Cancer

America’s cancer research system is under threat in one of its most productive moments. www.nytimes.com/2025/09/14/m...

14.09.2025 16:12 👍 0 🔁 1 💬 0 📌 0
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Generation of Lipid Nanoparticle mRNA Vaccines and Evaluation of Antigen-Specific CD8+ T-Cell Responses mRNA vaccines have revolutionized vaccine development against infectious diseases, as demonstrated by the rapid creation and deployment of vaccines for SARS-CoV-2. In this chapter, we present a protoc...

Latest from us: we detail the protocol we use to generate mRNA-LNPs and to study immune response in preclinical setting.
link.springer.com/protocol/10....

02.09.2025 23:01 👍 1 🔁 1 💬 0 📌 0
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Transient gene melting governs the timing of oligodendrocyte maturation Oligodendrocyte maturation is governed by an SOX6-dependent gene-melted chromatin state at multiple immaturity loci. Reducing SOX6 accelerates maturation, offering a potential strategy to regenerate myelin in diseases like multiple sclerosis.

Now online! Transient gene melting governs the timing of oligodendrocyte maturation

25.08.2025 14:59 👍 8 🔁 6 💬 0 📌 0
FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system - Nature Communications The homeostasis of myelin in the central nervous system is highly regulated, but the underlying mechanisms are unclear. Here, the authors show that the FBXW7 protein has a role in constraining myelin ...

www.nature.com/articles/s41...

21.08.2025 21:10 👍 4 🔁 8 💬 0 📌 0
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Epigenetic regulation of brain development, plasticity, and response to early-life stress Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress

Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq

06.08.2025 15:38 👍 76 🔁 28 💬 1 📌 1