bioRxiv Cell Biology

A general methodology for liver sinusoid fenestration analysis based on 3D electron microscopy data https://www.biorxiv.org/content/10.64898/2026.03.07.710307v1

Arrestin-3 scaffolds multiple MAP3Ks driving stress-induced JNK3 activation and cell death. https://www.biorxiv.org/content/10.64898/2026.03.09.710604v1

Immortalized AT2 Cell Lines from Healthy and IPF Lungs Enable 2D and 3D Cultures https://www.biorxiv.org/content/10.64898/2026.03.09.709900v1

Lung endothelial niche signaling governs self-renewal and fate transitions of human alveolar stem cells https://www.biorxiv.org/content/10.64898/2026.03.07.710316v1

Cellquant: a vibecoder's guide to image analysis https://www.biorxiv.org/content/10.64898/2026.03.09.710634v1

Microfluidic Separation of Adipocytes https://www.biorxiv.org/content/10.64898/2026.03.07.710291v1

A green fluorescent protein for live imaging in hyperthermophiles https://www.biorxiv.org/content/10.64898/2026.03.09.710647v1

CDK/mTOR-dependent phosphorylation of UBE2H restrains its charging with ubiquitin and regulates CTLH-dependent degradation https://www.biorxiv.org/content/10.64898/2026.03.07.710281v1

Chromosome segregation synchrony in S. pombe is noise-limited and arises without positive feedback https://www.biorxiv.org/content/10.64898/2026.03.09.710577v1

Modulating SPARC Expression in Mesenchymal Stem Cells Improves Secretome-Mediated Skin Regeneration and Wound Repair https://www.biorxiv.org/content/10.64898/2026.03.07.710278v1

imAgeScore, a Cell Painting-Based Predictor of Cellular Age for High-throughput Drug Screening Applications https://www.biorxiv.org/content/10.64898/2026.03.06.710056v1

Systematic real-time profiling of Salmonella type III effector translocation provides quantitative resolution of the T3SS-1/T3SS-2 secretion dichotomy https://www.biorxiv.org/content/10.64898/2026.03.06.710167v1

Actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion https://www.biorxiv.org/content/10.64898/2026.03.06.710140v1

Ribosome Molecular Aging Shapes Translation Dynamics https://www.biorxiv.org/content/10.64898/2026.03.08.710403v1

The human parasite, Toxoplasma gondii, is paralyzed without two components of the apical polar ring https://www.biorxiv.org/content/10.64898/2026.03.07.707822v1

MEF2D impairs mitochondrial respiration, glucose-stimulated insulin secretion, and survival in INS-1 β-cells. https://www.biorxiv.org/content/10.64898/2026.03.07.709963v1

Fluorescence anisotropy structured illumination microscopy for quantitative super-resolved mapping of cell microenvironment and cytoskeletal dynamics https://www.biorxiv.org/content/10.64898/2026.03.06.710005v1

Volumetric fluorescence microscopy-based quantitative comparison of murine tissue clearing using CUBIC protocols https://www.biorxiv.org/content/10.64898/2026.03.06.709534v1

High-throughput Single-cell Proteomics Enabled by Integrating nPOP-workflow with Quantitative Hyperplexing https://www.biorxiv.org/content/10.64898/2026.03.05.709467v1

Fasting primes small intestinal regeneration after damage via a microbiome metabolite chromatin axis https://www.biorxiv.org/content/10.64898/2026.03.06.710208v1

A Ubiquitin network safeguards cell identity by continuously degrading stem-cell related translational machinery https://www.biorxiv.org/content/10.64898/2026.03.06.709266v1

Presenilin 1 (PS1) located at mitochondrial inner membrane regulates mitochondrial cristae junction proteins arrangement and cristae formation in HEK293 cells https://www.biorxiv.org/content/10.64898/2026.03.05.709976v1

Wnt signalling controls abscission dynamics in mouse embryonic stem cells https://www.biorxiv.org/content/10.64898/2026.03.05.709800v1

Endosomal maturation is controlled by the trimeric Bulli-Mon1-Ccz1 GEF7 complex and Rab5-GTPase activating protein GAPsec https://www.biorxiv.org/content/10.64898/2026.03.05.709801v1

Developmental Elimination of Electrical Synapses by UNC-51/UNC-76-Mediated Vesicular Transport https://www.biorxiv.org/content/10.64898/2026.03.04.709731v1

Plasma membrane nanoscale dynamics of Arabidopsis leucine-rich repeat receptor kinase complexes https://www.biorxiv.org/content/10.64898/2026.03.05.709869v1

K-Ras controls asymmetric cell divisions from the primary cilium https://www.biorxiv.org/content/10.64898/2026.03.05.709789v1

Prophase Chromosomes Relocalizes to Nuclear Periphery for Protection in Depletion of Nucleoporin NPP-3/NUP205 Through the Spindle Assembly Checkpoint Activity, Centromere-Kinetochore Proteins and BAF-1-LEM-2 https://www.biorxiv.org/content/10.64898/2026.03.04.709728v1

FDA-approved drug library screen identifies antidepressants, antimicrobials, anti-COPD, and anti-CVD agents as blockers of NLRP3 inflammasome and sepsis in a sex-dependent manner. https://www.biorxiv.org/content/10.64898/2026.03.05.709979v1

The stem cell compartment in human oral mucosa and its activation in oral lichen planus. https://www.biorxiv.org/content/10.64898/2026.03.04.709521v1