Amélie Joly

Plus que quelques jours pour candidater. Rejoignez-nous!

Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...

📣First preprint of the lab📣 Did that really happen?😅

Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...

Pathways of Pain. @ameliejoly.bsky.social and I enjoyed writing this perspective on science.org/doi/10.1126/...
science.org/doi/10.1126/...

Induction of menstruation in mice reveals the regulation of menstrual shedding During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵

Merci 😁

Thank you Sébastien! I feel very lucky to be part of this great community 😁

Delighted to have given our annual prizes to these two rising stars in Neuroendocrinology 👏🏻

What an honour to receive the 2025 Thesis prize of @sneuroendo.bsky.social 🤩
Huge thanks to the scientific committee, to the Fondation Obélisque and to my incredible PhD supervisors @francoisleulier.bsky.social and @filipedevadder.bsky.social 🙏

Thank you very much Dafni 😊

Congratulations to first authors @ameliejoly.bsky.social and @lucasrebiffe.bsky.social for taking this project forward.
A big thanks to @frm-officiel.bsky.social and @agencerecherche.bsky.social for funding this work, and @igflyon.bsky.social for making the right environment for the research.

In normally growing juveniles, semaglutide improves glucose control without affecting growth.
But in stunted mice, it further impairs linear growth, revealing a key interplay between energy metabolism and the somatotropic axis during development.
Mechanistic, not clinical!

Delighted to share that our work has just been accepted in the Journal of the Endocrine Society 🤩
Ever wondered if semaglutide can interfere with growth? Check it out!
👇👇

Impressive talks from our ECRs for a symposium that they organized at our annual conference #SNE2025 🤩😍.

Many thanks @jne-editor.bsky.social!

👩‍🔬J'ai commencé un kit de démarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience

J'ai besoin de votre aide pour le remplir et donner de la visibilité aux chercheuses que vous connaissez et qui sont sur Bluesky !
▶️Taguez celles que vous connaissez, je les ajoute !

📢 We are looking for a sandwich student to join the lab of @irenemiguel-aliaga.bsky.social at the @crick.ac.uk for a 12-month placement starting July 2025!

Interested in how the 🐁 gut changes during pregnancy? Check the project and eligibility criteria here: www.crick.ac.uk/careers-stud...

Carola Vinuesa receives FEBS | EMBO Women in Science Award Carola Vinuesa, Principal Group Leader and Assistant Research Director at the Francis Crick Institute is to receive the 2026 FEBS | EMBO Women in Science Award for her scientific achievements as well ...

Congratulations to @carovinuesa.bsky.social on receiving the 2026 FEBS | @embo.org Women in Science Award.

She is recognised for her scientific achievements and her impact as a role model within the life sciences community.

www.crick.ac.uk/news/2025-09...

Learning about the latest findings in neurogastroenterology and gut motility at #NeuroGastro2025 ! 🧠🥪

Happy and proud to share this story! 🎉
We show that, when it comes to juvenile malnutrition, sex really matters ♂️♀️🐁
We also uncover a crucial, sexually dimorphic role of FGF21 in these adaptations 💥

👇👇👇

Live from international Fondation L'Oréal- UNESCO For Women In Science award ceremony 🎉 Congratulations to the five inspiring laureates ✨

Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...

Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...

Nothing like ending a day of stimulating science with beautiful live music performed directly at the @crick.ac.uk 🎶🔬✨
Who needs a concert hall when the concert comes to you?

NIH cancels its first and largest study centered on women The Women’s Health Initiative has produced numerous influential findings

Today in the USA, women are TWICE as likely to DIE giving birth than their mothers were a generation ago.
And TRUMP's War on Women continues with ending the landmark Women's Health Study: www.science.org/content/arti...

It's the beginning of a new adventure: I just started as a postdoctoral researcher at the @crick.ac.uk in the group of @irenemiguel-aliaga.bsky.social 🎉
I'll be working on #SexDifferences and reproductive remodelling of the gastro-intestinal tract in 🐭
Excited and grateful for this opportunity!

Congrats @lucasrebiffe.bsky.social 👏🏼🥳

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

Thousands gather across U.S. in Stand Up for Science events Scientists rally across the country in response to layoffs and funding cuts ordered by the Trump administration

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

On #WorldObesityDay 2025 we present a special focus issue: "Decoding the complex systems of obesity”. We explore organ cooperation, metabolic health & environmental factors like diet in obesity. www.cell.com/cell-metabol...

An organism-level quantitative flux model of energy metabolism in mice Yuan et al. built an organism-level flux model of energy metabolism describing circulating nutrients’ oxidation, interconversion, release from storage, and storage fluxes. The model revealed that circulating nutrients present higher cycling than oxidation…

Online now: An organism-level quantitative flux model of energy metabolism in mice

@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6

Happy 10th International day of women and girls in science 🎉👩🏼‍🔬
I'm convinced that the contributions of scientific women are crucial to build an inclusive, resilient and sustainable future 🌍
Join the @unesco.org campaign #EveryVoiceInScience to spread the word! 📢