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Linnea Smeds

@linneasmeds

Post Doc at Penn State University. Interested in conservation genomics, evolution, and BIRDS

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17.12.2024
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Latest posts by Linnea Smeds @linneasmeds

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Exploring #PAG33 and San Diego for the first time! If you're interested in knowing more about why bird microchromosomes are so hard to sequence, come by poster 287 this afternoon!

12.01.2026 18:11 ๐Ÿ‘ 11 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐Ÿงต5 Top Free Alternatives to BioRender for Scientific Illustrations!

These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs.

Save and share the post!

13.05.2025 19:55 ๐Ÿ‘ 677 ๐Ÿ” 349 ๐Ÿ’ฌ 32 ๐Ÿ“Œ 6
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I'm presenting a poster this afternoon at the Biology of Genomes #BoG25 - come by #254 in Biondi Hall if you wanna learn more about Non-B DNA motifs in great ape T2T genomes!

09.05.2025 15:08 ๐Ÿ‘ 9 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

5. The satellite SST1, which is a breakpoint in #Robertsonian translocations, is enriched in recombinogenic G4 motifs and Z-DNA.

6. Non-B DNA display species- and chromosome-specific trends at #centromeres.

24.04.2025 21:02 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

3. G4s and Z-DNA are enriched at #promoters and #enhancers, as well as at origins of replication.

4. #Repetitive sequences carry more non-B DNA motifs than non-repetitive sequences.

24.04.2025 21:02 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

1. Non-B forming sequence motifs are overrepresented at the newly added to #T2T genome regions for the autosomes, #X and #Y chromosomes.

2. Non-B DNA motif types have a high density on the short arms of #acrocentric chromosomes.

24.04.2025 21:02 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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My first first-author Post Doc paper together with Kateryna Makova just got published in the latest issue of Nucleic Acids Research: academic.oup.com/nar/article/...

Press release by Sam Sholtis: science.psu.edu/news/Makova4...

Artwork by Dani Zemba.

Key Findings below!

24.04.2025 21:02 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Complete sequencing of ape genomes - Nature Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evolutionary comparisons.

Nature research paper: Complete sequencing of ape genomes

https://go.nature.com/3EfWwqk

09.04.2025 16:55 ๐Ÿ‘ 59 ๐Ÿ” 24 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 3
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๐Ÿšจ New preprint!
We analyzed 39 bird genomesโ€”including 3 Mauritian species that bounced back from the brink of extinctionโ€”to explore genomic erosion in a comparative framework.
๐Ÿงฌ๐Ÿฆœ๐Ÿงฉ
๐Ÿ“„ www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social

10.04.2025 15:04 ๐Ÿ‘ 51 ๐Ÿ” 16 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.

A phylogeny of the 7 ape genomes that have now been completed from "T2T", with Homer Simpson representing mankind.

A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...

09.04.2025 21:31 ๐Ÿ‘ 156 ๐Ÿ” 77 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 3
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Complete sequencing of ape genomes - Nature Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...

My first PostDoc paper turned out to be this one: www.nature.com/articles/s41... (a small contribution to this massive effort - but glad to be part of it!)

09.04.2025 15:55 ๐Ÿ‘ 7 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Very cool work and beautiful cover by my PhD brother @jesperboman.bsky.social ๐Ÿ˜

09.04.2025 14:41 ๐Ÿ‘ 4 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Excellent scheduling according to me! โ˜•๐Ÿฝ๏ธโ˜•

21.03.2025 14:32 ๐Ÿ‘ 5 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

@tapani-hopkins.bsky.social @dvlrnr.bsky.social Uppdatering: Man kan maila till Alfred Kihlberg pรฅ Studjefrรคmjandet fรถr att anmรคla sig utan personnummer! (hans kontaktuppgifter ska finnas pรฅ anmรคlningssidan)

24.02.2025 16:15 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
A male pied flycatcher perching on a branch

A male pied flycatcher perching on a branch

๐Ÿ“ฃ New PhD position on flycatchers with @qvarnstromlab.bsky.social โ€” spread the word!

Combine bioinformatics, long-term datasets and field work to explore climate adaptation and speciation in the lovely flycatchers. Join us in Uppsala, Sweden! Apply by Mar 18: www.uu.se/en/about-uu/...

#ecoevojob

20.02.2025 20:14 ๐Ÿ‘ 38 ๐Ÿ” 41 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Jag ska prata med organisatรถren pรฅ mรฅndag, ska frรฅga dรฅ!

21.02.2025 20:19 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Oj det visste jag inte! Men det kan vara sรฅ att Studiefrรคmjandet behรถver det fรถr att fรฅ ersรคttning...

21.02.2025 20:16 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Linnรฉa Smeds: Djupdykning i vargens genetik Forskaren Linnรฉa Smeds berรคttar om vargstammens historia, genetiska utmaningar och sin forskning om inavel och skadliga mutationer. Fรถrelรคsningen lyfter ho

I don't know how many Swedish speaking contacts I reach here, but if anyone is interested in wolfs and conservation genomics, I'll give a popular science evening lecture about it next Thursday! That is European evening time. In Swedish..๐Ÿ‡ธ๐Ÿ‡ช www.studieframjandet.se/uppsala-lan/...

20.02.2025 13:21 ๐Ÿ‘ 7 ๐Ÿ” 2 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1

Really cool work by @jesperboman.bsky.social et al!

05.02.2025 14:48 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Bioinformatician/Computational Biologist // University of Oldenburg

Please spread! The newly established CF Genomics at UOL is re-advertising a position for a bioinformatician uol.de/en/job/bioin...

07.01.2025 09:13 ๐Ÿ‘ 2 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Lots of cool findings, especially the relation between non-B DNA motifs and centromeres/satellite repeats!

18.12.2024 20:10 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Kateryna Makova and I have a new preprint out on non-canonical DNA in human and ape T2T genomes: www.biorxiv.org/content/10.1...

Collaboration with Kaivan Kamali, Francesca Chiaromonte, Eduard Kejnovsky, and Iva Kejnovska. Graphical abstract by Dani Zemba.

18.12.2024 20:10 ๐Ÿ‘ 21 ๐Ÿ” 9 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1