Anna Golebiewska

Modelling brain tumours with organoids: towards precision medicine in neuro-oncology - Nature Reviews Neurology Organoids provide a useful model to capture the heterogeneity of brain tumours. Here, the authors assess current methodologies for generating organoids from various types of brain tumour and discuss h...

How can brain tumor organoids advance research, drug efficacy studies, and precision medicine? Check out our new review in Nature Reviews Neurology. doi.org/10.1038/s415...
@LIH_Luxembourg , @glioresolve.bsky.social, @FnrLux, #NET4BRAIN

🗣️You can NOW (at last) register for the Brain Tumor Meeting By The Sea which will be held in #StMalo from March 23 to March 25 here btmbts26.sciencesconf.org

🤩The keynote speakers are @annagolebiewska.bsky.social, #David_Castel and @benjaminwerner.bsky.social

poke @labsoap.bsky.social

🚨We have an opening for Data Scientists or Bioinformaticians using machine learning and AI with all kinds of molecular data to support cancer research. 🧬
Permanent position, fantastic team, exciting projects—what more could you ask for?
www.lih.lu/en/job/?valu...

Immunosuppressive mechanisms and therapeutic interventions shaping glioblastoma immunity - Nature Cancer In this Review, Golebiewska and colleagues summarize the main features of the immunosuppressive microenvironment in glioblastoma (GBM) and discuss how different therapeutic approaches reshape GBM immu...

Can immunotherapy ever work in #glioblastoma?

In a new #NatureCancer review, we share our perspective on current limitations and future directions:
www.nature.com/articles/s43...

#NORLUX, #LIH , @fnr.lu #TELEVIE, @glioresolve.bsky.social, @michael-platten.bsky.social

Happy to share a new #NORLUX study on how humanized patient-derived xenografts of #glioblastoma can be useful in investigating immunosuppression and clinically-relevant immunotherapy testing. See for more: www.biorxiv.org/content/10.1...
#immunotherapy, #preclinicalmodeling,

Integrative multi-omics combined with functional pharmacological profiling in patient-derived organoids identifies personalized therapeutic vulnerabilities of adult high-grade gliomas Background: Precision medicine has transformed cancer treatment by tailoring therapies to specific molecular aberrations. Integrating high-resolution multi-omics with high-throughput functional profil...

Precision medicine in high-grade gliomas? Using high-throughput drug screen in #NORLUX patient-derived organoids multi-omics and machine learning, we assessed pharmacogenomics: www.biorxiv.org/content/10.1...
@fnr.lu, #precisionmedicine, #organoids, #drugscreen, #pharmacogenomics, #braintumors

Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas Astrocytomas and oligodendrogliomas are slow-growing and treatment-sensitive IDH-mutant gliomas diagnosed at ages 30-50. Local tumor regrowth and treatment resistance is inevitable resulting in 3-10 y...

New preprint on longitudinal treatment response signatures in IDH-mutant glioma from the GLASS Consortium www.biorxiv.org/content/10.1...

📣 Have you heard? Registration for #EANO2025, taking place Oct 16-19, 2025 in #Prague (CZ) is open! Don’t miss out on this fantastic experience to meet experts in the field of #NeuroOncology. Early Bird fees available until July 31, 2025. 👉 eano.eu/eano2025/reg... #braincancer #medsky

New CAJAL course incoming!
Applications are now open #CancerNeuroscience (22 Sep – 10 Oct 2025) at the Bordeaux School of Neuroscience!
🔗More info: cajal-training.org/on-site/canc...
@varunvenkatesh.bsky.social, #AntonioPagano

🧠 Join the next #EANOYoungsters Journal Club on June 5, 16:30–17:30 CEST!
Discussing: "Rapid molecular profiling of CNS tumors" www.nature.com/articles/s41... (Patel et al., Nat Med 2025)
📍Free & open to all EANO members
🔗 www.eano.eu
#NeuroOncology #BrainTumors #JournalClub

One month left to register for the 2025 Early Career Researchers Conference!

In its fifth edition, this virtual conference has become a must-attend for early career researchers to discuss critical aspects of a scientific career in cancer research.

Don't miss it: eacr.org/conference/e...

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics - Nature Genetics Comparison of paired primary and recurrent glioblastomas at the single-cell transcriptomic level describes molecular and cellular trajectories associated with tumor recurrence, highlighting extensive ...

1/ Truly excited to share our new study that I had to privilege to co-lead during my PhD alongside great friends and collaborators @masashi-nomura.bsky.social, @kevin-johnson.bsky.social and Luciano Garofano, published at Nature Genetics @natureportfolio.nature.com!

www.nature.com/articles/s41...

Registration is OPEN for the next edition of The Tumour Ecosystem! 🎉

Taking place next March in Bergamo, this conference will cover the latest advances in research of the tumour microenvironment.

Learn more and register now: eacr.org/conference/t...

After a sold-out 2023 event, Goodbye Flat Biology has moved to a larger venue in Essen, Germany to make sure more of you can join us for what promises to be another fantastic event!

Join us for 3 days of excellent science and networking:
eacr.org/conference/g...

Discover insights into human glial development in organoid models & brain cancer with Dr. Steven Sloan from Emory University School of Medicine. Don’t miss this opportunity to explore cutting-edge neuroscience research!
📅 Monday, March 24, 2025
⏰ 2:00 – 3:15 PM (Paris time)
📍 Zoom – Register now!

🚀Abstract submission for #EANO2025 is open! Share your #NeuroOncology research at the 20th #EANO Meeting in Prague, Oct 16-19, 2025. We can't wait to see your contributions!
🗓️ Deadline: April 30, 2025, 23:59 CEST.
🔗 Details: www.eano.eu/eano2025/abs...
#btsm #braintumor

On March 10, 2025, Net4Brain is hosting a virtual conference Modelling Minds: Innovations in Preclinical Brain Cancer Research!
Join us here: zoom.us/j/9888368827...
Whole program: net4brain-cost.eu/rushmore_eve...
#Net4Brain #CA22103 #BrainCancerResearch #PreclinicalModels

Marta de Lucas and Soumi Mukherjee, our PhD candidates, presented their research posters at the Brain Tumor Microenvironment Symposium at @institutducerveau.bsky.social . Very exciting projects exploring how chemotherapy and ultrasounds influence the tumor microenvironment in glioblastoma 🧠

📢 Don’t miss the Highlights of EANO/SNO 2024 Webinar! Join our experts as they discuss key abstracts from #EANO2024 (Glasgow) & #SNO2024 (Houston), covering the latest in #NeuroOncology.
🗓️ March 7, 2025
⏱️ 6:30-7.30pm CET
Register now: eano.eu/eanowebinar/

@neuroonc.bsky.social

For all funs of tumor plasticity: @EACR 's upcoming conference on persister cells. Do not miss the abstract deadline on 20th January.

🧵Just in time for
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social

@svenjaktetzlaff.bsky.social

1/15

Poster for EACR conference on Cancer Neuroscience on 14-16 October, 2025 in Bilbao, Spain featuring various speakers.

SAVE THE DATE

Discuss the interactions between the nervous system and cancer in our first @helloeacr.bsky.social conference on #CancerNeuroscience next year!

🗓️ Oct. 14-16, 2025
📍Bilbao, Spain

📥 Abstracts due June 30, 2025
📥 Register by Sept. 15, 2025

For more info, visit eacr.org/conference/c...

Treatment of glioblastoma patients with personalized vaccines outside clinical trials: Lessons ignored? The treatment of patients with glioblastoma remains a challenge. Several large clinical trials of the last decades have failed and had—in retrospect—been b

"A thoughtful continuation of the clinical development of immunotherapeutic strategies within the framework of clinical trials is required to provide relevant new insights that can eventually lead to a clear delineation of its value in clinical practice"

academic.oup.com/neuro-oncolo...