Sinead O'Sullivan

If you’re in San Diego for #Sfn25, come by on Wednesday at 2 pm for a session on oligodendrocyte pathophysiology and repair mechanisms in multiple sclerosis, Alzheimer’s, and Parkinson’s disease. Would be great to see some familiar (and new) faces there!

NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression How NLRP3 impacts Alzheimer’s disease (AD) is unclear. McManus et al. find that NLRP3 is located at mitochondria where it regulates microglial metabolism. Depletion or chronic pharmacological inhibiti...

I am thrilled to share our latest article that has been published in @cp-immunity.bsky.social. We describe a new role for NLRP3 outside of its #inflammasome complex, where it can regulate microglial #metabolism & key metabolites that affect the epigenetic landscape(1)
www.cell.com/immunity/ful...

The story of the human brain, with Jim Al-Khalili | The Darwin Day Lecture 2025

We're excited for the Darwin Day Lecture on 7 February with
@jimalkhalili.bsky.social. Book your tickets and join us as we track the brain's 700 million-year evolutionary history, and explore how it developed from simple nerve cells to a remarkably complex human system. humanists.uk/events/darwi...

Postdoc (f/m/x) 1383/2025/1

🚨We are hiring! Postdoc position available at the DZNE Bonn, to study the role of oligodendrocytes in the progression of Parkinson's disease!🧠🔬
jobs.dzne.de/de/jobs/1014...