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Andy Purkiss

@andypurk

X-ray crystallographer and structural biologist at the Francis Crick Institute. Cats not dogs. Also interested in railways, Sci-Fi and Star Trek (amongst other things). Type 1 Diabetic

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Latest posts by Andy Purkiss @andypurk

Don't go stepping into any wardrobes.

09.03.2026 22:23 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

If you work in #characterisation, #modelling, #AI/ML, or #manufacturing, this exploitation workshop brings together the people actually building those solutions. If you want to influence how these technologies land in real life you should be there and meet project @heu-matchmaker.bsky.social

08.03.2026 13:10 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Drop something GREEN πŸ¦–πŸπŸ–€πŸ‰πŸŠ

07.03.2026 13:58 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Screenshot showing a range of beamlines at Diamond with 'active' connections available.

Screenshot showing a range of beamlines at Diamond with 'active' connections available.

When you've been making good use of Diamond before end of the run. #DLSMX #DLS

07.03.2026 13:49 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Miss Marple, the BBC series from the late 80s and early 90s.

07.03.2026 00:28 πŸ‘ 6 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Dreaming, the opening track from Eat to the Beat.

www.youtube.com/watch?v=TU3-...

Just edging out Hanging on the Telephone from Parallel Lines.

07.03.2026 00:10 πŸ‘ 4 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0

I could go to all that trouble and then just tread on them anyway as they cross my front path during the next rain shower...

02.03.2026 09:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Schindler's List, with the couple of notable exceptions.

01.03.2026 23:43 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Both b) and c).

27.02.2026 23:29 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Take a star trek episode and replace one word in the title with β€œbitch” (or β€œbitches”).

Bitch

as in

'Bitch and Jalad… at Tanagra.'

27.02.2026 18:47 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I get my news from a reliable source

27.02.2026 10:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

25.02.2026 22:25 πŸ‘ 51 πŸ” 54 πŸ’¬ 1 πŸ“Œ 0

Bah, that is just Daphne's influence.
My first cat, when I was a child, was a ginger (ex-)tom who could open the back door from both sides. Exit was easy as the door opened outwards, but coming in back in needed more thought. Front paws to push down the handle, back legs pushing off the frame/wall.

25.02.2026 17:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Not seen the Shakespeare quoting Klingons yet. I'd also have the Heptapods from Arrival.

25.02.2026 01:37 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

And a lamp to push off when the human isn't paying attention or you're feeling bored . πŸˆβ€β¬›

24.02.2026 20:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Crocheted model of a two-domain, mostly helical protein next to Caroline’s hand. Each domain is about the same size as her hand.

Crocheted model of a two-domain, mostly helical protein next to Caroline’s hand. Each domain is about the same size as her hand.

If you’re at #BPS2026, go look at Poster B49. Caroline Cannistra has some very detailed all-atom simulations of HIV capsid protein, and SHE CROCHETED A MODEL OF IT to demonstrate the dynamics.

23.02.2026 22:35 πŸ‘ 41 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

Or just use GBP and USD as these clearly define the currency (unlike Β£ and $).

23.02.2026 10:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

There is no way that any GenAI would be able to generate and evolve either of the characters of Schlock or Ch'vorthq. Let alone their discussion of the Tub of Happiness near the start of Schlock Mercenary's long run or the later addition of Tequila to the mix!

23.02.2026 00:58 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Star Trek: Into Darkness especially. Why include Khan and flip the roles of Kirk and Spock at the end? It made no sense.
At least Star Trek Beyond was more original, as Into Darkness could have been.

18.02.2026 22:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Banksy πŸ–€ you, but can see the bottom of the bowl? 😼

16.02.2026 11:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

1) Gwen Stacy aka Spider-Gwen

2) One of the mysterious Blue Wizards (maybe before they went to the east).

3) Diana Prince aka Wonder Woman

4) D'Vana Tendi

15.02.2026 00:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

My sadly departed Bella, when I lived in Stockwell, sat beneath the nest which a bird had made in an air vent and systematically slaughtered the young family, one per day, finishing with the mother. Along with (mostly) dead rats, she earned the nickname Slay Bells! She did slow down a bit with age.

13.02.2026 17:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Same here. Sometimes people tell me I'm talking loudly, especially in a noisy environment, but it seems normal to me.

13.02.2026 15:40 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Do you still have an aerial for the TV? If so, then Freeview should be available and is what I use.
Freely is more or less the WiFi version of Freeview (there's no on-demand option with Freeview) and needs to be included with the TV.

11.02.2026 12:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Age verification?

When I first saw Star Wars, in the cinema, Han shot first.

11.02.2026 03:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Of course I studied the classix.
(Although I mainly played the black and white Dragon 32 version).

10.02.2026 22:14 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Surprisingly the heating is still working, most of the time, which was unexpected when the problem first surfaced.

10.02.2026 21:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Currently without hot water here awaiting parts for the boiler and a slot for the engineer to return and fit them! The shower at work has been standing in.
Fitting a new cold-fed shower is on the list but needs a new electric consumer unit as I still have old school wire fuses.

10.02.2026 21:05 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

An old one:
The Caffeine Mantra
"It is by caffeine alone I set my mind in motion. It is by the beans of Java that the thoughts acquire speed, the hands acquire shakes, the shakes become a warning. It is by caffeine alone I set my mind it motion."
Not sure about shakes, they seem to come when I stop!

10.02.2026 10:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Star Trek VI: The Undiscovered Country.

09.02.2026 15:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0