Shivani Rajhansa

How do single transcription factors prevent lineage differentiation?
In this issue of Blood, the second paper of my PhD is published. We show that MECOM, a key HSC TF, maintains stem cell state by preventing change through repression of CEBPA. #hemesky ashpublications.org/blood/articl...

New ‘off-the-shelf’ immunotherapy shows promise for treating high-risk childhood leukaemia Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for in...

NEW: Scientists in the @roylab-oxford.bsky.social have co-led the development of a new type of immunotherapy that could improve outcomes for infants and children with high-risk leukaemia 🧪

#ChildhoodCancerAwarenessMonth

@oxfordpaediatrics.bsky.social | @medsci.ox.ac.uk

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Congratulations Dorien!!! 🎉🎉

Oh wow a goldmine!! Thanks Dorien:)

Hey Marlies! So good to see you on here :)🦋

Woohoo!! latest bluesky addition from rotterdam is fellow Delwel lab PhD student @jengelberts.bsky.social 🥳 and now we FINALLY have enough people for our own starter pack go.bsky.app/N8zjL6y 😁 #HemeSky

go.bsky.app/FrzB2bf let's make this list the more complete possible! If you have any recommendation, please send it this way!

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...

Tried and tested - very pretty histogram overlays and dot plots for flow cytometry data!

Happy to be here!! All thanks to @dpastoors.bsky.social :)