@poldresden
We are the Cluster of Excellence Physics of Life (PoL) at TUD Dresden University of Technology @tudresden.bsky.social @dfg.de. Our goal is to unravel the principles underlying the organization of living matter. https://physics-of-life.tu-dresden.de
PoL is at the DPG @dpgphysik.bsky.social spring meeting in Dresden. Visit us in Tent C until Thursday afternoon!
Special thanks to the @brugueslab.bsky.social for the cool data on our Apple Vision Pro devices! Come check it out ๐ค๐
We are super excited to see a fellow Cluster of Excellence @tudresden.bsky.social joining Bluesky๐ฆ. Welcome, RECยฒ! ๐
๐Congratulations to the Friedrich group at PoL @friedrich-group.bsky.social for a new collaboration published in PRX Life!
Read the paper here: journals.aps.org/prxlife/abst...
Here's a beautiful #microscopy image from our PoL Photo Competition ๐ธ
๐จโ๐ฌ ๐ฌยฉ๏ธ Image taken by Yogishree Arabinda Panda, PhD student in the Fischer-Friedrich group @fischerfriedriclab.bsky.social
๐ Caption: A SEM micrograph of a mitotically arrested HeLa cell with visible filopodia membrane reservoirs
โก๐ฉโ๐ฌElectrical signals are key for promoting organ regenerative growth, a new study!
Out now in Science Advances, from the Mateus group @ritamateus.bsky.social at PoL and @mpi-cbg.de along with the lab of Frank Jรผlicher @mpipks.bsky.social
Read the news here: tud.link/7jzptz
Video:ยฉ๏ธ Mateus group
New paper alert!๐คฉSuper proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread ๐งตhttps://www.science.org/doi/10.1126/sciadv.aec0687
Just in time for Friday, the next image from our annual PoL Photo Competition ๐ธ
๐จโ๐ฌ ๐ฌยฉ๏ธ This #microscopy image was taken by Shuzo Kato, a PhD student in the Bruguรฉs lab @brugueslab.bsky.social @mpi-cbg.de
๐ Caption: The mitotic spindle in a zebrafish embryo under oxygen depletion (DCX-GFP).
Mikrotubuli-Aster in einem zytoplasmatischen Extrakt des Krallenfrosches Xenopus laevis
How do cells establish and maintain their individuality with such precision? ๐ฆ A team led by Jan Bruguรฉs at the Cluster of Excellence @poldresden.bsky.social at TUD Dresden University of Technology has uncovered fundamental mechanisms that shed light on this question.
โน๏ธ tu-dresden.de/tu-dresden/n...
๐Exciting new findings out in @nature.com today by the Bruguรฉs lab! @brugueslab.bsky.social @mpi-cbg.de
๐จโ๐ฌ The authors describe how physical instability of the cytoskeleton works with the cell cycle to drive organization in the embryo during early development
Read our press release: tud.link/kctu4s
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this๐งต www.nature.com/articles/s41... ๐คฉ
@poldresden.bsky.social @mpi-cbg.de
Here's the next submission from our annual PoL Photo Competition ๐ธ
๐จโ๐ฌ ๐ฌยฉ๏ธ This beautiful image was designed by Shuzo Kato, a PhD student in the Bruguรฉs lab @brugueslab.bsky.social
๐ Caption: A mitotic spindle; acrylic on canvas.
Congratulations to researchers in the group of @anne-grapin.bsky.social, PoL PI and director at @mpi-cbg.de for publishing an exciting new method to create functional acinar cells, opening new avenues for organoid research. ๐งซ
๐ฅ Exciting BTS from our new film project!
As we start our new chapter at PoL, weโre creating some films to showcase our cutting edge research, career opportunities, and more..
Hereโs a sneak peek of what to expect. We canโt wait to share the films with you, coming soon! ๐ฑโจ
๐PoL PI Elias Barriga @eliasbarrigalab.bsky.social was recently featured in an exciting news piece about bioelectricity research by Quanta magazine @quantamagazine.bsky.social.
Curious? Check it out below! โก๐จโ๐ฌ
๐New findings in PRX from @fischerfriedriclab.bsky.social at PoL overturn a long-standing belief in biophysics about living systems.
Using AFM, the authors have found that time irreversibility is a better signature of cellular activity than effective temperature
Read our news here: tud.link/wu3t36
New paper out: AFM-tip fluctuations inside the actin cortex reveal that effective temperature can remain unchanged while time-irreversibility/entropy production drop (turnover inhibition). #CellMechanics #ActiveMatter #Nonequilibrium
@poldresden.bsky.social @tudresden.bsky.social
Great story from @brugueslab.bsky.social. Congratulations, especially to @alisonkickuth.bsky.social. It was an honour to serve on the Thesis Advisory Committee! @mpi-cbg.de @poldresden.bsky.social #stuffthatmatters
Das Bild zeigt den Embryo des Zebrabรคrblings wรคhrend des ersten Zellteilungszyklus. Das Strukturprotein Aktin ist markiert und visualisiert den Zellrand sowie die Teilungsfurche. Das Bild stellt eine Zeitreihe dar, die mit dunklem Orange (vor der Teilung) beginnt und mit fortschreitender Teilung รผber helleres Orange bis zu Weiร รผbergeht.
Die mechanische Ratsche: Forscher:innen vom Exzellenzcluster @poldresden.bsky.social haben einen neuen Mechanismus der Zellteilung entdeckt. ๐งซ Die in @nature.com verรถffentlichten Ergebnisse zeigen, wie die Teilung รผber einen "Ratschen"-Mechanismus vorangetrieben wird.
โน๏ธ tu-dresden.de/tu-dresden/n...
Really happy to see my PhD first-author paper published in @nature.com! Iโm very grateful to have worked with such a great team. Huge thanks to Urลกa Urลกiฤ, Michael Staddon, and Jan Bruguรฉs, as well as the @brugueslab.bsky.social, and the @poldresden.bsky.social and @mpi-cbg.de community!
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread ๐งต and at www.nature.com/articles/s41... ๐คฉ
@poldresden.bsky.social @mpi-cbg.de
Image ยฉ๏ธ Alison Kickuth @alisonkickuth.bsky.social
๐Exciting findings out today in Nature @nature.com from the PoL group of Jan Bruguรฉs @brugueslab.bsky.social! The authors describe a new mechanism driving cell division during early development in #zebrafish, fundamentally altering our view of the process.
Read the press release: tud.link/2s3bxj
The sarcomere is the elementary contractile unit of muscle, driving all volunatry motion and heart beat in animals. How these โcytoskeletal crystalsโ self-assembly is only partly understood.
๐๏ธOur review on how to build muscle is out in
@biophysicalreviews.bsky.social: The Physical Basis of Sarcomere Assembly. We critically review past models and discuss a new mechanism that unifies past ideas, suggesting tension-driven self-organization. With
@frankschnorrer.bsky.social & Kolley-Kรถchel
Continuing the entries from our annual Photo Competition ๐ธ
๐จโ๐ฌ ๐ฌยฉ๏ธ This #microscopy image was captured by Arthur Boutillon from the Campร s lab @campaslab.bsky.social
๐ Caption: Rhodamine dextran diffusing between cells, labelling extracellular space, in embryonic zebrafish.
Researchers from @merihuchlab.bsky.social, together with colleagues from @labshevchenko.bsky.social and clinicians from Dresden and Leipzig developed a patient-specific human periportal liver assembloid. Publication in @nature.com. Full news: www.mpi-cbg.de/news-outreac...
Onto the next submission from our annual Photo Competition! ๐ธ
๐ฉโ๐ฌ๐ฌยฉ๏ธ This #microscopy image was captured by Marie Jagemann, a 'Physics of Life' MSc student
๐ Caption: Early zebrafish embryos forming the shape of an adult fish.
Here's another beautiful submission from our annual Photo Competition ๐ธ
๐จโ๐ฌยฉ๏ธThis #microscopy image was captured by Jaime Espina from the Barriga lab @eliasbarrigalab.bsky.social
๐ Caption: A cell cluster performing durotaxis and exhibiting differences in tubulin stabilization (nuclei shown in blue).
Weโre excited to share the entries from our annual Photo Competition ๐ธ
๐จโ๐ฌ Here's a stunning image by Shuo-Ting Yen from the PoL Campร s lab @campaslab.bsky.social
Caption: Developing zebrafish retina from the zebrabow line, captured with a Zeiss LSM980 confocal microscope using an oil paint filter.
๐จJob Opportunity for #Postdocs!
Weโre searching for a talented postdoctoral scientist to join our team, and explore meiotic spindle self-organization at the crossroads of biology and physics ๐ฌ๐ฉโ๐ฌ
๐ Curious? Apply now: tud.link/7fmgeg
๐๏ธ Deadline: January 14, 2026
Please share with your network!
Congratulations to Yasmin, a 'Physics of Life' MSc graduate now a PhD student in the PoL Friedrich group @friedrich-group.bsky.social for being awarded the Ehrenfried Walter von Tschirnhaus Award last week! ๐
