Institute of Macromolecular Chemistry

Smart biosensors help detect inflammation early in patients with joint replacements A team led by Elena Tomšík from the Department of Conducting Polymers at the IMC is developing smart biosensors with higher accuracy, smaller dimensions, and broader diagnostic capabilities based on s...

Newly developed smart biosensors by @imcprague.bsky.social will enable faster, more accurate inflammatory markers detection.

“They can reveal inflammation before it fully develops and help precisely identify the causative agent of the infection,” Elena Tomšík says.

www.imc.cas.cz/en/news/smar...

UV-Induced Crosslinking of Poly(tetramethylene itaconate): Toward Sustainable Polymer Networks - Journal of Polymers and the Environment Herein, a novel potential ink for 3D bio-printing, composed of itaconic acid and 1,4-butanediol, was prepared and analyzed. This study investigated the effect of curing time on UV-crosslinked polymer ...

#new_paper: UV-Induced Crosslinking of Poly(tetramethylene itaconate): Toward Sustainable Polymer Networks
@springernature.com: sustainable polymer networks
doi.org/10.1007/s109...

Charge-Shifting Copolymers of 2-(N,N-Dimethylamino)Ethyl Acrylate and 2-Hydroxyethyl Acrylate via RAFT Polymerization: Balancing the Charge Content and Biological Response Synthetic polycations are key components for engineering polyelectrolyte complexes with wide-ranging biomedical potential. However, the high cytotoxicity of fully charged polycations remains a major l...

#new_paper: Charge-Shifting Copolymers of 2‑(N,N‑Dimethylamino)EthylAcrylate and 2‑Hydroxyethyl Acrylate via RAFT Polymerization: Balancing the Charge Content and Biological Response
@pubs.acs.org: copolymers
doi.org/10.1021/acsa...

#new_paper: HPMA polymers as functional excipients in dermal nanoformulations of imiquimod
@elsevierconnect.bsky.social: HPMA polymers
doi.org/10.1016/j.ij...

Nitrogen‐Doped Borane Cluster Network for High‐Performance Supercapacitors Under Universal pH Conditions Nitrogen-doped borane cluster network was prepared as a porous electrode material, featuring 1–2 nm micropores and specific surface area up to 626 m2 g−1. It delivers outstanding supercapacitor perfo...

#new_paper: Nitrogen-Doped Borane Cluster Network for High-Performance Supercapacitors Under Universal pH Conditions
@chemistryeurope.bsky.social: Borane cluster, high-performance supercapacitors
doi.org/10.1002/cssc...

#new_paper: Thermoplastic Starch Composites with Highly Exfoliated Nano-Clay Fillers and Excellent Barrier Properties
@mdpiopenaccess.bsky.social: Starch composites, nano-clay fillers
doi.org/10.3390/ma19...

#new_paper: Surface-engineered porous carbon electrode with polyaniline for high-energy density symmetric and Zn-ion hybrid supercapacitor
@elsevierconnect.bsky.social: carbon electrode, supercapacitor
doi.org/10.1016/j.es...

A Modular Synthetic Strategy toward Fast-Growing Poly(amide-carbosilane) Dendrimers Based on Click Chemistry and Organic Solvent Nanofiltration Dendrimers, constituting a prominent class of monodisperse and multivalent macromolecular compounds with outstanding properties, are characterized by regular and highly branched three-dimensional arch...

#new_paper: A Modular Synthetic Strategy toward Fast-Growing Poly(amidecarbosilane) Dendrimers Based on Click Chemistry and Organic Solvent Nanofiltration
@pubs.acs.org: nanofiltration
doi.org/10.1021/acsp...

Excited-state dynamics of colloidal gold nanoshells functionalized with trimethoxysilylazachalcones In this study, we present a new synthetic approach to obtain trimethoxysilylazachalcones, a family of donor–acceptor chromophores exhibiting strong intramolecular charge-transfer behavior. Their disti...

#new_paper: Excited-state dynamics of colloidal gold
nanoshells functionalized with trimethoxysilylazachalcones
@rsc.org: gold, nanoshells
doi.org/10.1039/D5TC...

Single-Nanoparticle Luminescence Nanothermometers with Enhanced Sensitivity in Physiological Temperature Range In this paper, we presented the unique optical properties of monodispersed and uniform luminescence nanothermometers (LNTs), composed of core (NaYF4:Yb3+,Er3+) and core–shell (NaYF4:Yb3+,Er3+@NaYF4) u...

#new_paper: Single-Nanoparticle Luminescence Nanothermometers with Enhanced Sensitivity in Physiological Temperature Range
@pubs.acs.org: nanothermometers
doi.org/10.1021/acso...

#new_paper: Morphology control in benzoic imine-linked polymer-drug conjugates for adaptive drug delivery and enhanced in vivo efficacy
@elsevierconnect.bsky.social: drug delivery
doi.org/10.1016/j.eu...

#new_paper: Increasing Tc retention during nuclear waste vitrification: Structural and phase change analysis of Al-source behavior by 27Al MAS NMR
@elsevierconnect.bsky.social: nuclear waste vitrification
doi.org/10.1016/j.jn...

#new_paper: Modification of Chitosan with (−)-Gossypol and (−)-Gossypol Acetic Acid Using Free-Radical Grafting Method
@mdpiopenaccess.bsky.social: chitosan, radical grafting method
doi.org/10.3390/ijms...

Structural dependence of the solution behavior of HPMA-based polymers Water-soluble polymers are extensively studied materials in the field of biomedical chemistry research. This study investigates the behavior of methacrylamide-based homopolymers and copolymers with li...

#new_paper: Structural dependence of the solution behavior of HPMA-based polymers
@rsc.org: HPMA-based polymers
doi.org/10.1039/d5py...

Targeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl4-intoxicated mice Carbon tetrachloride (CCl4) metabolism results in the production of highly reactive free radicals and consequent liver tissue damage, making CCl4-induced liver injury an ideal model for studying drug ...

#new_paper: argeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl4-intoxicated mice
@rsc.org: berberine, intoxicated mice
doi.org/10.1039/D5NA...

#new_paper: Long-term chemical composition of clinker-free hydraulic binder from metakaolin, anhydrite II and lime: 27Al and 29Si MAS NMR, DTA-TG-MS, XRD and SEM investigation
@elsevierconnect.bsky.social: clinker-free hydraulic binder
doi.org/10.1016/j.ri...

#new_paper: Bisphosphonate-Modified Polymer-Coated NaYF4:Yb,Er,Pr Upconverting Nanoparticles for Cell Imaging: Synthesis, Physicochemical Characterization and Biosafety
@wiley.com: polymer coating, nanoparticles, biosafety
doi.org/10.1002/jbmb...

Polymeric Nanocarriers of a Monosubstituted Tetraphenylporphyrin Sensitizer Intended for Photodynamic Therapy and Tumor Imaging To effectively combat advanced cancers, next-generation nanomedicines should combine both therapeutic and diagnostic functions. In this study, we developed stimulus-responsive theranostics systems bas...

#new_paper: Polymeric Nanocarriers of a Monosubstituted Tetraphenylporphyrin Sensitizer Intended for Photodynamic Therapy and Tumor Imaging
@pubs.acs.org: nanocarriers,therapy, tumor
doi.org/10.1021/acso...

#new_paper: XPS analysis of zwitterion polymer brushes: discrepancies, degradation and methodological considerations
@elsevierconnect.bsky.social: zwitterion polymer brushes
doi.org/10.1016/j.ap...

Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach - Scientific Reports Scientific Reports - Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach

#new_paper: Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach
@Scientific reports: glutamate uncovering
doi.org/10.1038/s415...

Aminolyzed Polycaprolactone Nanofiber Scaffolds with Visible Light-Activated Sterilization for Tissue Engineering Applications New photoactive nanofiber materials based on an aminolyzed polycaprolactone membrane with demonstrated cytocompatibility were developed. Two photoactive compounds, the photosensitizer Rose Bengal and ...

#new_paper: Aminolyzed polycaprolactone nanofiber scaffolds with visible light-activated sterilization for tissue engineering applications
@pubs.acs.org: nanofiber scaffolds
doi.org/10.1021/acs....

TYRAY-Functionalized Alginate Bioinks for 3D Bioprinting Support Stem Cell Culture and Endothelial Network Formation 3D bioprinting is transforming tissue engineering by enabling spatial arrangement of cells and cell aggregates within supportive hydrogels. Among available materials, alginate remains widely used for ...

#new_paper: TYRAY-Functionalized alginate bioinks for 3D bioprinting support stem cell culture and endothelial network formation
@pubs.acs.org: 3D bioprinting
doi.org/10.1021/acsb...

#new_paper:Incorporation KLAK peptide in anticancer therapy: Achieving cancer cell apoptosis via
mitochondrial membrane disruption using homing domains introduction and other modifications
@elsevierconnect.bsky.social: anticancer therapy
doi.org/10.1016/j.ej...

#new_paper:Incorporation Nanomedicines for delivery of cytarabine: effect of carrier structure and spacer on the anti-lymphoma efficacy
@mdpiopenaccess.bsky.social: nanomedicines
doi.org/10.3390/poly...

#new_paper:Incorporation of humic acid as a way to improve the adsorption performance of polyaniline-based cryogels towards safranin
@elsevierconnect.bsky.social: cryogels
doi.org/10.1016/j.re...

#new_paper: Cryopolymerization in the presence of sucrose as a way to control morphology, conductivity and mechanical properties of polyanilinepoly (vinyl alcohol) cryogels
@elsevierconnect.bsky.social: Cryopolymerization, cryogels
doi.org/10.1016/j.sy...

#new_paper: Tannic and boric acid crosslinked glycerol–citrate polyesters: Structural, mechanical and biological performance
@elsevierconnect.bsky.social: Polyesters, performance
doi.org/10.1016/j.eu...

#new_paper: Polymeric micelles in advanced photodynamic therapy: Design, delivery and translational prospects
@elsevierconnect.bsky.social: photodynamic therapy
doi.org/10.1016/j.ij...

#new_paper: Theranostic verteporfin-conjugated upconversion nanoparticles for cancer Treatment
@mdpiopenaccess.bsky.social: nanoparticles, cancer
doi.org/10.3390/nano...

#new_paper: Nickel oxide hole transport layer for perovskite solar cells: preparation via pulsed laser deposition with simulation and experimental insights
@elsevierconnect.bsky.social: perovskit sollar cells, experimental
doi.org/10.1016/j.va...