New publication!!📑
Congrats to the Carell lab on their new paper:
"One-Step and universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U"
🔎Read more here: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Publication alert!!📑
Congrats to the @dikiclab.bsky.social and Beli labs on their joint #SFB1361 publication, covering how DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality.
🔎Read the paper here: www.science.org/doi/10.1126/...
SFB 1361 member - Dr Andriana Kotini - will present a poster at "The Evil Within: Regulation and Repair of Endogenous DNA Damage" (IMB Mainz, 10-13 March 2026)👩🏫
Join us to connect, discuss and collaborate!
Details & registration: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
SFB 1361 member - Dr Natalie Schindler (@scientistwithheart.bsky.social) - shares a preview of her short talk at our upcoming conference 👩🏫
Dive into details at @imbmainz.bsky.social in Mainz this 10-13 March 2026!
Register now: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
Preprint alert!!📑
We're happy to share a new preprint from our associated member, Dr Maximilian Reuter (@reuterlm.bsky.social), on
"Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution"
🔎Read more here: www.biorxiv.org/content/10.6...
SFB 1361 member - Dr Carolin Wagner - will present a short talk at our upcoming conference 👩🏫
Don't miss out and come join her at @imbmainz.bsky.social!
Registration closes 02 Feb → www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
Our speaker - Prof. Helle Ulrich - invites fresh perspectives on DNA repair & genome stability. 🧬
Continue the conversation at our conference "The Evil Within: Regulation and Repair of Endogenous DNA Damage." (IMB Mainz, 10–13 Mar 2026).
Register → www.sfb1361.de/dnarepairconf2026
Meet the speakers!🎤
Session 6 "Replication Stress"
Chunlong Chen (Institut Curie) and Nynke Dekker (@nynkedekkerlab.bsky.social, Univ. of Oxford).
Registration via www.sfb1361.de/dnarepairconf2026 is ongoing!
See you in March at @imbmainz.bsky.social!
#ISC26DNArepair #SFB1361 #IMBMainz
Meet the speakers!🎤
Session 5 "Features Driving Vulnerability"
Tony Cesare (@thecesarelab.bsky.social, CMRI), Julien Duxin (Univ. of Copenhagen), Fumiko Esashi (Univ. of Oxford), Lorenza Penengo (Univ. of Zurich) & Francesca Storici (Georgia Tech)
#ISC26DNArepair #SFB1361 @imbmainz.bsky.social
Meet the speakers!🎤
Session 4 "Telomeres"
Fabrizio d'Adda di Fagagna (IFOM), Stephane Marcand (iRCM), Patricia Opresko (Univ. of Pittsburgh) & Teresa Teixeira (IBPC).
Register now via www.sfb1361.de/dnarepairconf2026 and come listen to them in Mainz!
#ISC26DNArepair #SFB1361 #IMBMainz
Loving @drewberry.bsky.social's beautiful animation of DNA break repair by HR - featuring the MRN complex architecture and function inspired by the research from @hopfnerlab.bsky.social!
Dive into the science behind it🧬
www.sciencedirect.com/science/arti...
www.nature.com/articles/s41...
Meet the speakers!🎤
Session 3 "Ageing, Disease & Therapy"
Robert Hänsel-Hertsch (@epistrucstab.bsky.social, CMMC), Peter McKinnon (St. Jude's), Sven Rottenberg (@svenrottenberg.bsky.social, Univ. of Bern) & Björn Schwer (Univ. of California).
See you in Mainz!
#ISC26DNArepair #SFB1361 #IMBMainz
Publication alert!! 📃
Congratulations to the @hopfnerlab.bsky.social on the great work!
🔎Read the paper here: www.sciencedirect.com/science/arti...
Meet the speakers!🎤
Session 2 "Gene Regulation & Chromatin Dynamics"
Sophie Polo (@polosophie.bsky.social, Univ. Paris Cité), Viviana I. Risca (@vivrisca.bsky.social, Rockefeller), Kikue Tachibana (MPI of Biochemistry) & Zhiguo Zhang (CUIMC).
Join us in March!
#ISC26DNArepair #SFB1361 #IMBMainz
📢Abstract deadline extended to Mon, 15 Dec, 23:59 CET!
Good news! You now have a few more days to submit your abstract to present a short talk or poster at the IMB & SFB 1361 conference.
📑Find more info here: sfb1361.de/dnarepaircon...
#ISC26DNArepair #SFB1361 #IMBMainz
Meet the speakers! 🎤
Introducing Session 1 "Double Strand Breaks", featuring
Petr Cejka (@cejkalab.bsky.social) from the Institute for Research in Biomedicine Bellinzona, CH and Boris Pfander from TU Dortmund, DE.
Register now and come hear them at @imbmainz.bsky.social!
#ISC26DNArepair #SFB1361
Don't forget - Early Bird Registration and Abstract Submission closes on 1 December.
Register now via www.sfb1361.de/dnarepairconf2026
We can’t wait to see you in March!
#ISC26DNArepair #SFB1361
📃Just published: new joint #SFB1361 publication by the Luke and Ulrich labs!
The article focuses on how Rad53 regulates RNase H1, which promotes DNA replication through sites of transcription-replication conflict.
🔎Find out more here:
www.sciencedirect.com/science/arti...
We are excited to share that our #SFB1361 alumni, Dr Gabriel M. C. Longo, received a Walter Benjamin Fellowship to support his postdoctoral research in the Kleinstiver lab at Harvard Medical School/Massachusetts General Hospital, Boston.
Congratulations! 🎉🎉
📃Publication alert!!
Congrats to the Krämer lab on their new publication:
"Identification of a Proteolysis-Targeting-Chimera that Addresses Activated Checkpoint Kinase-1 Reveals its Non-Catalytic Functions in Tumor Cells"
🔎Read more about it here: onlinelibrary.wiley.com/doi/10.1002/...
We’re excited to have Lorraine Symington and Stephen West as our keynote speakers - covering how cells repair DSBs during replication and how chromosomes are rebuilt via HR.
IMB & SFB 1361 Conference, 10–13 March 2026. Registration is live! #ISC26DNArepair #IMBMainz
New publication!! 📑
Congrats to the Ulrich and @hopfnerlab.bsky.social labs on their latest work exploring how the INO80 chromatin remodeller facilitates DNA damage bypass via postreplicative gap repair.
🔎Read the paper here:
www.embopress.org/doi/full/10.1038/s44318-025-00580-4
Registration is open!
Join us at IMB Mainz from 10–13 March 2026 for the 2nd International IMB & SFB 1361 Conference on "The Evil Within: Regulation and Repair of Endogenous DNA Damage".
Don't miss this conference and register now via www.sfb1361.de/dnarepairconf2026
#ISC26DNArepair #IMBMainz
It is with deep sadness that we share the news of the unexpected passing of our dear colleague and associated member Dr Nard Kubben last week.
We extend our heartfelt condolences to his family, friends, and all those who had the privilege of knowing him.
Publication alert!!📑
Congratulations to the @hopfnerlab.bsky.social, @yilanfan.bsky.social and @filizkuybu.bsky.social on the great work!
Read about it here: www.nature.com/articles/s41...
Yesterday’s full-day workshop co-organised with @imbmainz.bsky.social focused on building a strategic approach to research funding for postdocs.
We’re proud to stand behind our postdocs as they shape the future of research!
#PAWde #PostdocAppreciationWeek2025 #IMBMainz
📃Just published: new #SFB1361 publication by the Krämer and Christmann labs!
The article focuses on how the deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2.
Find out more here:
🔎 www.nature.com/articles/s41...
We’re excited to welcome Susanne Gerber from the University Medical Center Mainz as an associated member of the #SFB1361! 🎉
Her expertise in bioinformatics and cutting-edge nanopore sequencing protocols will advance genomic and epigenomic research within our network.
We‘re proud to share that our #SFB1361 PhD student, Yilan Fan from the @hopfnerlab.bsky.social, has been awarded a poster prize at the CNIO-CaixaResearch Frontiers Meeting “Machines on DNA and RNA: A Molecular Mechanistic Perspective“ held on 28-30 May 2025 in Madrid, Spain.
Congrats! 🎉
Last week our #SFB1361 members gathered in Würzburg to discuss and plan for the 3rd funding period.
This 3-day retreat led to many fruitful discussions and fresh ideas! Now its time to put these ideas to work! 🔬⚗️🧬
#scientificretreat #planning #DNArepair
