Paul K. Sue, MDCM FIDSA, FPIDS

👍 Twice daily Chlorhexidine self care reduces asymptomatic bacteriuria by 56% following #KT > great discussion by #HannahNam on the #PROTEKT study #IDWEEK2025

👍 Fantastic study by #WilliamCappucio on #Short-Course (<10D)duration of antibiotics as non-inferior to prolonged (>10 d) antibiotics in uncomplicated gram negative bacteremia among Adult #SOT. #IDWEEK2025

Counseling immunocompromised patients on minimizing 🆔 risks? Don't reinvent the 🛞!

@astinfo.bsky.social @ast-idcop.bsky.social has Power2Save Safer Living Patient Information sheets! Translations and more topics in upcoming years!

transplantid.net?patient_educ...

Highway to the donor danger zone? Please join the #TxID crew Tues 8am in B312 for 'Should I Take This Donor?' 🤔 w donor-derived infx experts Stephanie Pouch and Emily Blumberg dropping knowledge on all your donor-related q's ♥️ 🫁 🫘 @aneeshkmehta.bsky.social #IDSky @idweek.bsky.social #IDWeek2025

📣 The #IDSA #IHCoP will be hosting the #IHCoP #TxID Networking Reception tomorrow at 5PM at the #OmniAtlantaHotel (M4 Grand Ballroom D) followed by a 👍 curated #PosterWalk. Click here 👇 to register www.surveymonkey.com/r/IHCoP2025 (or just show up!) #AllWelcome #IDWEEK2015

🥳 A huge crowd gathered at the #IHCoP #BugHub stage to listen to #AlpanaWaghmere, #StellaRadosta & #GabrielMotoa discuss #ChallengingCases in #TxID!! #IDWEEK2025

Thanks as always for these very helpful links! Great resource for both fellows and current practitioners in #TID #TxID #IDSky

👍 Excellent session this morning at the #BugHub by #JeremyWalker hosted by @AndreaRuff and @EmilyEichenberger on #BridigingTheGap between General & #TxID! #IHCOP #IDWEEK2025

Packed house difficult mold infections - very hard to say definitively if combination therapy is useful for Mucor per Dimitrios Farmakiotis , recommended to avoid use outside of stepdown therapy etc, #IDWeek2025 @idweek.bsky.social #TxID @sarahhammond.bsky.social

🥳 Awesome 2 catch up w/ #HopkinsFam @tcrowellmd.bsky.social & #AmitaGupta at #BigBash @#IDWEEK2025!!

Prolonged applause for Dr Demetri Daskalakis, formerly of the CDC, winner of the HIV Medical Association Transformative Leader Award… #IDSky #IDWeek #IDStrong

Blue slide announcing PIDS Award winner, Walter Orenstein, MD, FPIDS

Dr. Orenstein stands at the IDWeek lectern delivering acceptance remarks

Walter Orenstein, MD, FPIDS, an influential figure in public health and immunization efforts, including policy and hesitancy, is the Pediatric Infectious Diseases Society (PIDS) 2025 Walter T. Hughes Distinguished Physician Award honoree.
pids.org/2025/10/19/p...

🙌 Congratulations to #CindySears for her receipt of the #FlemingLifetime Achievement award @ #IDWEEK2025! An amazing legacy and absolutely inspiring!! #IDWEEK2025

#IDWEEK is Underway!! >> #JavierMunoz kicking off #IDWEEK with selections from #Hamilton, and a call for the ID community to continue it's mission to use science to impact the world 🌎 #IDWEEK2025 #WeAreID

Large Language Model Influence on Diagnostic Reasoning This randomized clinical trial evaluates the diagnostic performance of physicians with use of a large language model compared with conventional resources.

A friend sent this article to me today.

It feels like a good moment to remind us: the LLM outperformed physicians on STRUCTURED cases.

Someday the AIs may perform better than us in the unstructured, messy, real-world patient encounter...but that day is not today.🩺🛟

jamanetwork.com/journals/jam...

Donor-derived Mycoplasma and Ureaplasma infections in lung transplant recipients: A prospective study of donor and recipient respiratory tract screening and recipient outcomes Mycoplasma hominis and Ureaplasma species are urogenital mollicutes that can cause serious donor-derived infections in lung transplant recipients. Best practices for mollicute screening remain unknown...

This is a nice and informative prospective study of donor-derived Mycoplasma and Ureaplasmain lung transplant recipients from our Duke Colleagues. Nicely done Patrick Tam! #TxID #IDSky www.amjtransplant.org/article/S160...

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. In a multicenter, non...

🔥BALANCE RCT🔥
74 hospitals in 7 countries
3,608 patients
A 7-day course of antibiotics for hospitalized patients with bloodstream infections was non inferior to 14d within a 4% prespecified margin for mortality at 90 days #idsky
www.nejm.org/doi/full/10....

Use of 2024-2025 COVID-19 Vaccines ... This report describes the Advisory Committee on Immunization Practices’ recommendations for the 2024-25 COVID-19 vaccines.

💉 For my #PedsTID friends >> wondering if folks are advocating multiple doses of the 2024-2025 COVID19 booster for your previously fully 💉 #Immunocompromised 👶? If so, how many more? 🙏 www.cdc.gov/mmwr/volumes...

🆕️🔥Treatment of Invasive Pulmonary Aspergillosis and Preventive and Empirical Therapy for Invasive Candidiasis in Adult Pulmonary and Critical Care Patients. An Official American Thoracic Society Clinical Practice Guideline #idsky
www.atsjournals.org/doi/abs/10.1...

Got a cool #TxID case?

Let @maricarmalinis.bsky.social know! See below for more details.

👍Fantastic study 👀 at whether #shorterisbetter in Neutropenic Bacteremia in adults. >80% GNB with almost 18% MDRO, profound neutropenia in 83% of enrollees & post therapy Abx PPX in 65%. Adequate source control in 70%-100%. No diff in relapse or ☠️ if <10 vs > 10 ABX days. #IDSky #TIDSky

Want to learn about the treatment of RVI in immunocompromised patients?

Join us for the next @ESCMID.bsky.social ESGICH/ESGREV webinar on the treatment of RVI.

Chairs: Hans Hirsch and @michaelisonmd.bsky.social

Talks by: Pauline Vetter, Jose Luise Pinana, Fareed Khawaja

How to not be completely wrong about air filters A new RCT of HEPA filters for residential care homes gets heads spinning

Excellent analysis of what happens when a clinical trial is under powered. In this example, it's the use of air purifiers in nursing homes and preventing respiratory tract infections.

Results suggest it might work. Or it might not.
@apsmunro.bsky.social

open.substack.com/pub/alasdair...

💩 Ugh -- ".. only 12.1% of NDM-producing isolates were susceptible to cefiderocol using the 2024 EUCAST version 14.0 DD breakpoint. Ceftazidime/avibactam and aztreonam synergy was seen in 87.5% of isolates tested..." In some settings, empiric use in MBL -producing isolates may be inappropriate...

IDSA Immunocompromised Host Community of Practice The purpose of the Immunocompromised Host Community of Practice (COP) is to create a community that

The @idsainfo.bsky.social IHCOP welcomes all who are involved in the care of immunocompromised hosts. We have a great opportunity to advance the field, build and sustain the TID workforce. Please sign
Up 🤓 my.idsociety.org/volunteeropp...

The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/

US health officials report 1st case of new form of mpox in a traveler Health officials say they have confirmed the first U.S. case of a new form of mpox that was first seen in eastern Congo.

Health officials in California have confirmed the first case of mpox clade I in the US. Patient is a returning traveller's who traveled to eastern Africa. This is not unexpected because the world is interconnected and there are ongoing outbreaks of clade I mpox in Africa.
apnews.com/article/mpox...

We have found the opposite 2 be true during this 👶outbreak. Incorrectly obtained NP swabs (not reaching the OP) have been false (+) 2 begin w/ only to turn (+) when retested in the PICU. And kids w/ progression on empiric S.pneumo, GAS & Staph coverage have ultimately required Azithro + steroids.

Great point!

We often advocate for a unifying diagnosis (Occam’s razor), but in people with immunocompromise, it’s important not to disregard Hickam’s dictum; “Patients can have as many diseases as they damn well please!”

#Medsky #IDSky #TxIDSky

pommel horse guy from us olympics mens gymnastics team resting with his eyes closed before his turn to compete at the olympics

All pediatricians and infectious diseases doctors right now
#PedsSky #IDSky #MedSky