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Canadian VIGOUR Centre

@cvcualberta

The Canadian VIGOUR Centre (CVC) is an academic research organization at the University of Alberta dedicated to enhancing cardiovascular health.

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Latest posts by Canadian VIGOUR Centre @cvcualberta

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New meta-analysis data suggests rethinking transfusion strategies for patients with heart attack & anemia. Restrictive strategies were linked to higher cardiac mortality & lower 6-month survival.

Learn about this research & more in our 2025 Annual Report: thecvc.ca/annual-repor...

12.03.2026 17:36 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Pooled data from the VICTOR & VICTORIA trials demonstrates vericiguat reduces CV death & HF hospitalizations across the HFrEF spectrumโ€”from stable to recently worsened cases.

Learn about this research & other highlights in the 2025 CVC Annual Report: thecvc.ca/annual-repor...

05.03.2026 19:08 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Sodium Restrictions May Only Benefit Patients at Low Risk of HF, With Justin Ezekowitz, MD | HCPLive Ezekowitz discusses his recent secondary analysis of the SODIUM-HF trial, highlighting the MAGGIC analysis data that implied a very limited benefit.

We spoke with Justin Ezekowitz, MD, to discuss his recent analysis of the SODIUM-HF trial, which indicated that dietary salt limitations may only benefit patients at the lowest risk for heart failure, contrary to popular belief.

Watch now:

20.02.2026 15:00 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Weโ€™re pleased to share our 2025 Annual Report: The Arteries of Innovation.

Innovation thrives on the circulation of diverse ideas. Discover how the CVC translates high-quality data into clinical solutions bridging the gap from discovery to care.

Read the report hereโžก๏ธ: thecvc.ca/annual-repor...

18.02.2026 17:28 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Two graphs compare bleeding with abelacimab vs. rivaroxaban. Graph A: bar graph shows incidence rate per 100 patient-years stratified by age. Graph B: probability of major bleeding vs. age for rivaroxaban and abelacimab pooled dose.

Two graphs compare bleeding with abelacimab vs. rivaroxaban. Graph A: bar graph shows incidence rate per 100 patient-years stratified by age. Graph B: probability of major bleeding vs. age for rivaroxaban and abelacimab pooled dose.

Among older patients with #AtrialFibrillation, abelacimab reduced major or clinically relevant bleeding vs rivaroxaban, with a greater absolute risk reduction in those aged โ‰ฅ75 years. bit.ly/4alEy1P

06.02.2026 14:00 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Registration is open for the next webinar in our ASCVD Education Series, taking place Thursday, January 29, 2026, at 8:00 p.m. ET. Join us as experts explore evidenceโ€‘based strategies to enhance patient outcomes and support best practices in ASCVD management.
Register today๐Ÿ”—https://bit.ly/3ZynKiT

27.01.2026 17:22 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Coronary Reperfusion in Patients With ST-Elevation MI Requiring Transfer This Viewpoint evaluates the evolution of ST-elevation myocardial infarction guidelines on reperfusion choices and the evidence that adherence to timely reperfusion recommendations affects outcomes in...

In this @jamacardiology.com .com viewpoint, Drs. Armstrong, Bainey, & Granger advocate for aligning #STEMI time metrics with current first-point-of-contact capabilities to ensure optimized outcomes for all patients, regardless of geographic location.

jamanetwork.com/journals/jam...

21.01.2026 23:31 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Vericiguat in Heart Failure: Insights From the VICTOR Trial - American College of Cardiology

The VICTOR study results complement those of the VICTORIA by extending the evidence base for vericiguat in a contemporary lower-risk, well-treated ambulatory #HFrEF population.

Explore more insights from the VICTOR trial โžก๏ธ https://bit.ly/4blPC0O #HeartFailure

06.01.2026 21:13 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The winter issue of the Canadian Cardiac Chronicle Newsletter is now available!

Read more about our current trials, research highlights, & other recent news & updates here: mailchi.mp/bed47c9edc60...

16.12.2025 18:59 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Now accepting applications! The CVC Scholar Program is a unique training opportunity for early-stage investigators focused on cardiovascular disease research.

Learn more & apply โžก๏ธ: thecvc.ca/programs-and...

#cardiosky #cardiology

27.11.2025 16:30 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
American Society of Nephrology Kidney Week 2025 
Original Article | Nov. 7, 2025 | NEJM.org 
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis 

Fig. 1A. A Serious Cardiovascular Events 

The NEJM identity sits at the bottom.

American Society of Nephrology Kidney Week 2025 Original Article | Nov. 7, 2025 | NEJM.org Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis Fig. 1A. A Serious Cardiovascular Events The NEJM identity sits at the bottom.

In the PISCES trial involving participants receiving hemodialysis, fish oil (nโˆ’3 fatty acids) was compared with corn-oil placebo. The rate of serious cardiovascular events was lower with daily fish-oil supplementation. Full trial results: nej.md/49zWuqo

@asnkidney.bsky.social | #KidneyWk

07.11.2025 16:36 ๐Ÿ‘ 25 ๐Ÿ” 11 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 6
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Meet the U of A's Fall 2025 Canada Research Chairs

Congratulations to CVC Co-Director Dr. Padma Kaul, who has been named Tier 1 Canada Research Chair in Women and Childrenโ€™s Cardio-Metabolic Health. ๐Ÿ‘

www.ualberta.ca/en/the-quad/...

31.10.2025 20:05 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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In STEMI patients with multivessel disease, reduced LVEF increases ischaemic risk โ€” but the COMPLETE trial showed complete revascularisation reduces major CV events regardless of LVEF. #cardiosky #medsky #LVEF #cardiology
eurointervention.pcronline.com/article/impa...

24.10.2025 10:17 ๐Ÿ‘ 1 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐Ÿšจ Just published! This guideline provides multi-disciplinary clinical teams with practical recommendations for SGLT2is, MRAs, ARNI and drugs with GLP-1 receptor agonist activity.

Read the guideline here: onlinecjc.ca/article/S082...

#Cardiosky #HeartFailure

20.10.2025 14:00 ๐Ÿ‘ 3 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Vericiguat Improves HFrEF Regardless of Background Therapy, With Justin Ezekowitz, MD | HCPLive Ezekowitz spotlights improvement in cardiovascular mortality and heart failure hospitalization despite a failure to achieve the primary endpoint of VICTOR.

At #HFSA2025, we spoke with Justin Ezekowitz, MD, co-director of the Canadian VIGOUR Center, to discuss his analysis of background therapies in the VICTOR trial of vericiguat in HFrEF.

Watch now:

18.10.2025 14:00 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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โฃ๏ธThe Fall 2025 issue of the CVC Chronicle newsletter is now availableโฃ๏ธ

Read about our current trials, research highlights, & other recent news/updates here: tinyurl.com/3w4srx67

08.10.2025 16:34 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Maternal asthma a risk for babies, study shows A University of Alberta-led research team has identified an association between asthma in pregnant women and adverse outcomes for their newborns, including preterm birth, low birth weight and caesarea...

Women with asthma, particularly active asthma, are at higher risk for preterm birth, low birth weight, & C-section, highlighting the need for improved asthma monitoring & management during pregnancy. @wchriuofa.bsky.social @stollerykids.bsky.social @ualberta.bsky.social

06.10.2025 16:23 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Dr. Moorthy reviewing the WHO global action plan for clinical trial ecosystem strengthening at the 4th Annual ACT meeting in Cape Breton, NS. We are making progress in Canada but lots of work to do!
@cvcualberta.bsky.social @csnscn.bsky.social @ualberta.bsky.social

25.09.2025 12:03 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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New analysis published in @jcardfail.bsky.social: applying the 5-STAR risk stratification method to VICTORIA trial data revealed a greater treatment effect for vericiguat on the composite endpoint of CV death or HF hospitalization.

Read more โžก๏ธ: authors.elsevier.com/a/1llYy3pkRz...

18.09.2025 16:32 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Happy to have had the chance to contribute to this amazing collaborative work led by @sandeepsahaymd.bsky.social and Dr Ray Benza

06.09.2025 02:48 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Figure highlighting selected opportunities for promotion of CKM health and prevention of heart failure at the individual, health-care system and community, and population and policy levels. CKM=cardiovascular-kidney-metabolic. Copyright: 2025 Elsevier Ltd. All rights reserved.

Figure highlighting selected opportunities for promotion of CKM health and prevention of heart failure at the individual, health-care system and community, and population and policy levels. CKM=cardiovascular-kidney-metabolic. Copyright: 2025 Elsevier Ltd. All rights reserved.

Heart failure affects more than 55 million people worldwide. ๐Ÿซ€

A new Lancet Series, presented at #ESC2025, serves as a call to action for clinicians, health systems, and governments to prioritise the primary prevention of heart failure. tinyurl.com/2sty9386

29.08.2025 11:46 ๐Ÿ‘ 12 ๐Ÿ” 9 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 1
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Late-breaking science from VICTOR & VICTORIA trials presented at #ESCCongress add to growing body of evidence surrounding vericiguat in treating patients with HFrEF. Read more: https://bit.ly/4lTUNXE
#HeartFailure

30.08.2025 12:50 ๐Ÿ‘ 1 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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In #HFrEF, quadruple therapy (ARNi, ฮฒ-blockers, MRA, #SGLT2i) improves survival. Adding #vericiguat may offer a modest ~0.7-year gain, though findings are exploratory, as they are derived from a secondary endpoint of a single trial https://bit.ly/4mE83Rp

#JACC #ESCCongress #WCCardio

30.08.2025 06:35 ๐Ÿ‘ 6 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The AURORA study is currently recruiting adults & adolescents with type 1 diabetes (T1D) & caregivers for an advisory group. Share your experience navigating the Alberta healthcare system & help us create a vital T1D knowledge hub!

Learn more โžก๏ธ: thecvc.ca/aurora-recru...

21.08.2025 19:48 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Priorities for lung transplantation research: a James Lind Alliance priority-setting partnership between patients, caregivers, and clinicians in Canada This study employed the James Lind Alliance Priority Setting Partnership methodology to identify and prioritize research priorities in lung transplantation through engagement of pre- and post-lung tra...

Excited to finally share our
James Lind Alliance
#Top10 Research Priorities for #LungTransplantation ๐Ÿซ๐Ÿ”ฌ๐Ÿ‘ฉ๐Ÿฝโ€๐Ÿ”ฌ

@ualberta.bsky.social
@ubcmedicine.bsky.social
@umontreal.ca @uhnresearch.ca @ucalgarymed.bsky.social

www.jhltopen.org/article/S295...

05.08.2025 13:59 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Cardiac Biomarkers Equally Apt to Rise in COVID-19, Influenza Patients who are hospitalized for either viral infection should be screened for myocardial involvement, experts say.

Patients hospitalized with influenza are just as likely as COVID-19 patients to have signs of myocardial involvement. Lead study author Finlay McAlister said the findings show a need to screen and monitor patients more closely. www.tctmd.com/news/cardiac...

02.08.2025 13:30 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New in @jaccjournals.bsky.social: A secondary analysis of the VICTORIA trial investigates the impact of geographic variation and Human Development Index on heart failure outcomes. ๐Ÿซ€ ๐ŸŒ

Read more here: www.sciencedirect.com/science/arti...

15.07.2025 17:51 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐Ÿ’ญ Review of transcatheter aortic valve insertion (#TAVI) clinician opinions on the CCS Post-TAVI Driving Guidelines: is a 1-month driving restriction period overly cautious? Read more โฌ‡๏ธ
cjcopen.ca/article/S258...
#CJCO #OpenAccess

25.06.2025 17:20 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Among patients with opioid-associated out-of-hospital cardiac arrest, chest compression and ventilation CPR was associated with a higher odds of favorable neurologic outcomes at hospital discharge.

ja.ma/4l7We4q

17.06.2025 16:43 ๐Ÿ‘ 4 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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Iโ€™m Aware That Iโ€™m Rare: Jason Weatherald, MD (524) the phawareยฎ interview

Dr. Jason Weatherald explains how your everyday clinic visits can help shape the future of pulmonary hypertension treatment. @phaware.bsky.social podcast ep 524 @phacanada #phawareMD @teamphhope @albertaphdoc.bsky.social @ualberta.bsky.social medium.com/p/im-aware-t...

10.06.2025 13:22 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0