Manchester Breast Centre

Breakthrough In A Blink - Preventing Breast Cancer In Pre-Menopausal Women A drug approved for use in other conditions could be repurposed to prevent breast cancer in women before the menopause.

A new study reveals a drug approved for use in other conditions could be repurposed to prevent breast cancer in women before the menopause.

In this short video, Non-Clinical PhD student Flor, breaks down the research findings: https://ow.ly/EXsx50Yl0Fe

Brilliant two days at Prevent Breast Cancer Research Conference 2026 & great to have so many from MBC team on the program.
We are proud of our partnership with @preventbc.bsky.social & excited about our breast cancer prevention research in the newly created PBC Research Unit @mcrcnews.bsky.social

🔬 February 11 – International Day of Women and Girls in Science 🧪
Meet some of the inspirational scientists and researchers from the Manchester Breast Centre 👩‍🔬
@mcrcnews.bsky.social @uom-dcs.bsky.social @cruk-mi.bsky.social
#womeninscience #IDWGIS2026

#transitionconsultancy #researchgrant #humanspecificresearch #breastcancerresearch | Centre for Human Specific Research On World Cancer Day 2026, we’re delighted to announce that we have awarded Dr Hannah Harrison at the The University of Manchester a Transition Consultancy Grant Award for the human-specific research s...

Great news for MBC PI, Dr Hannah Harrison on World Cancer Day 2026 👏
Thanks to the Centre for Human Specific Research for this grant which will allow Hannah to further develop human specific models & reduce reliance on animal products in her breast cancer research 👩‍🔬
www.linkedin.com/posts/centre...

🚨Applications are closing soon for our MB-PhD scheme

If you're a University of Manchester, Leeds or St Andrews medical student looking to combine your clinical training with a research PhD, check out our latest opportunities.

📅 Deadline: 9 March
🔗 https://ow.ly/GJQN50XU79k

New Research in Girls Aloud singer Sarah Harding’s name aims to stop breast cancer before it starts The second phase of a groundbreaking breast cancer study created in the name of Girls Aloud singer Sarah Harding, has seen the appointment of a senior research fellow.

A new research fellowship created in Sarah Harding’s name aims to stop breast cancer before it starts 💙

Funded by The Christie Charity, Dr Hannah Harrison has been appointed as the Sarah Harding Young Women’s Breast Cancer Fellow

Read the full story 👇
www.christie.nhs.uk/the-christie...

Thank you so much for organising the Christmas lab Olympics Gillian, well done to all the competitors and congratulations to the winning team team 🏆

I'm presenting some of my postdoc work, 'The ageing lung microenvironment in metastatic and dormant ER+ breast cancer' next week at the @britsocimm.bsky.social congress.

Come along to part one of the 'Inflammation in cancer' session at 11am on Weds 3/12 if you're there!

#BSI25 #ImmunoSky

New study uncovers potential way to prevent breast cancer in pre-menopausal women - Manchester Cancer Research Centre A new study funded by Breast Cancer Now and supported by Prevent Breast Cancer, reveals a drug approved for use in other conditions could be repurposed to prevent breast cancer in women before the men...

A new study from Manchester Breast Centre shows ulipristal acetate – a drug used on the NHS – could prevent breast cancer in pre-menopausal women with high genetic risk.

This could lead to non-invasive prevention strategies, offering hope to thousands.

🔗 www.mcrc.manchester.ac.uk/new-study-un...

Anti-progestin therapy targets hallmarks of breast cancer risk - Nature Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing epithelial–stromal remode...

A MBC team has found that anti-progestin therapy could help prevent breast cancer before menopause.
The anti-progestin drug blocks progesterone’s effects, lowering breast density & reducing cells that can turn into aggressive triple-negative breast cancer.
Published in Nature doi.org/10.1038/s415...

From everyone at the Manchester Breast Centre, we want to express our deepest condolences on the passing of Jo Taylor. Jo was truly remarkable and an inspiration to us all 💔

Congratulations to Anthony Wilby, winner of the Tony Howell Award for best presentation and Yuxi Zhou winner of the Charles Streuli Award for best poster. All of today's talks and posters were outstanding.

Congratulations on your great talk Gillian 👏

Huge congratulations to @frances-turrell.bsky.social for being awarded the American Association for Cancer Research, Pelotonia and Victoria’s Secret Global Fund for Women’s Cancers Career Development Award 👏
www.aacr.org/professional...

The Manchester Breast Centre (MBC) Symposium 2025 is underway @manchester.ac.uk.
Thank you to our sponsors for supporting this event and our breast cancer research - Beckman Coulter, Illumina, Thistle Scientific, Abcam & Fischer Scientific #breastcancerresearch

🚨Applications are open for our MB-PhD scheme! If you're a University of Manchester, Leeds or St Andrews medical student looking to combine your clinical training with a research PhD, check out our new MB-PhD projects. 📅 9 March 2026

🚨Applications are open for our MB-PhD scheme!

If you're a University of Manchester, Leeds or St Andrews medical student looking to combine your clinical training with a research PhD, check out our new MB-PhD projects.

📅 9 March 2026
🔗https://crukcentre.manchester.ac.uk/opportunity_category/mb-phd/

3rd PhD project being advertised in the @frances-turrell.bsky.social lab! Utilising liver fibrosis models to translate our findings in the lung to other critical sites of breast cancer metastasis and dormancy 🧪

@mcrcnews.bsky.social
@mcr-breastcentre.bsky.social

#ImmunoSky

Identifying vulnerabilities of E-cadherin-deficient tumour cells to uncover novel treatment approaches for lobular breast cancer - Cancer Research UK Manchester Centre Non-Clinical PhD Studentship. Applications now open.

And another project, generating and characterising a model of lobular breast cancer 🧪

Great opportunity to do cool science in a fun environment! Please share to anyone interested and feel free to reach out

@frances-turrell.bsky.social
@cruk-mi.bsky.social
@mcr-breastcentre.bsky.social

(MRC DTP) Investigating how semaphorins reshape the immune microenvironment in ER+ breast cancer to impact immunotherapy response and drive metastasis at The University of Manchester on FindAPhD.com PhD Project - (MRC DTP) Investigating how semaphorins reshape the immune microenvironment in ER+ breast cancer to impact immunotherapy response and drive metastasis at The University of Manchester, li...

Two really exciting PhD projects currently being advertised in our group. One project on how tumour cells shape the TME in breast cancer and how this impacts immunotherapy 🧪

@frances-turrell.bsky.social
@mcrcnews.bsky.social
@mcr-breastcentre.bsky.social

Applications are now open for our 2026 entry
@cancerresearchuk.org -funded #CancerResearch #PhD opportunities! 🧑‍🔬🧪

Interested in applying for a Clinical or Non-Clinical PhD? Explore our available projects.

🔗 crukcentre.manchester.ac.uk/study/resear...

📆Deadline: Monday 17th November 2025

Thank you to The Oddfellows and Prevent Breast Cancer for visiting us today and for supporting Anthony Wilby's PhD project.
@preventbc.bsky.social @mcrcnews.bsky.social @cruk-mi.bsky.social

Thank you to everyone who joined us for the MBC Prevent Breast Cancer (PBC) Special Symposium & PBC Research Unit Launch today.
Special mention to all @preventbc.bsky.social, Andy Burnham Mayor of Greater Manchester,Geoff Lindeman & Jane Visvader from @wehi-research.bsky.social & all our researchers

Starting September with an excellent seminar by Professor Roger Gomis from @irbbarcelona.org on “ER+ Breast cancer metastasis cell fate mapping”.
Thank you for visiting us in Manchester and sorry about the rain!
@mcrcnews.bsky.social @uom-dcs.bsky.social @cruk-mi.bsky.social

Congratulations to consultant breast surgeons Ashu Gandhi & James Harvey who have been appointed Manchester Academic Health Science Centre (MAHSC) Honorary Clinical Chairs "for making an outstanding contribution to their clinical profession, with demountable national and/or international impact"👏

Matrix stiffness drives alterations in aldehyde metabolism, inducing DNA damage and transformation Scientific Reports - Matrix stiffness drives alterations in aldehyde metabolism, inducing DNA damage and transformation

It's great to see the thesis work of Matt Jones, Hannah Percival, Alis Hales, Amber Wood & Heyuan Sun published. They have shown that increased mammographic density reduces a breast epithelial cell’s ability to metabolise aldehydes leading to increased mutagenesis or DNA damage
rdcu.be/ezXXr

HES1 oscillations are required for cell cycle progression and re-entry in oestrogen receptor positive breast cancer cells Long-term recurrence in breast cancer is driven by reactivation of dormant disseminated tumour cells (DTCs) and remains a major clinical challenge, particularly in oestrogen receptor positive (ER⁺) tu...

Proud to present a nice story on ER+ breast cancer dormancy regulation from our former PhD student Ollie Cottrell, in collaboration with Nancy Papalopulu's group in Biological Sciences, University of Manchester

Proteomics Identifies Osteomodulin as a Promoter of Breast Cancer Bone Metastasis via CDK1 Activation Metastasis to different organs remains the main cause of mortality in breast cancer. Molecular predictors of metastasis are limited as well as therapeutic options. Here, we conducted quantitative prot...

An interesting story and great science from our current and former PhD students, Sara Cabral and Joe Parsons, in collaboration with Ciara O'Brien in Manchester and Chiara Francavilla in Denmark as well as colleagues in Sheffield, Hungary and the USA.

Thank you to Professor Valerie Speirs for visiting us from @uniofaberdeen.bsky.social and giving a terrific talk on "Biological Insights into Breast Cancer in Men", hosted by Dr Sacha Howell at the @mcrcnews.bsky.social with @uom-dcs.bsky.social & @cruk-mi.bsky.social
#breastcancer #research

Naga Munchetty - 22/07/2025 - BBC Sounds Naga Munchetty features news, experiences, and big name interviews from around the UK.

Thanks to Naga Munchetty for inviting Prof @robclarkelab.bsky.social from Manchester Breast Centre, Tristan Loraine from Lobular Moon Shot Project, patients & other guests to speak about lobular breast cancer on BBC Radio 5 Live today
BBC Sounds 🔗 starts at 12:04pm www.bbc.co.uk/sounds/play/...

Congratulations to Erin Durston-Hillyer and Finlay Spencer, newly graduated with Integrated Masters Degrees in Medical Biochemistry and Pharmacology, respectively, having successfully completed their research projects in the MBC Breast Biology group, supervised by Prof @robclarkelab.bsky.social