vervoortlab.bsky.social

Stalling of elongating Pol II triggers Ser7 phosphorylation in trans to drive transcription recovery DNA is scattered with obstacles that stall RNA polymerase II (Pol II) and block the production of full-length transcripts. Two mechanisms are known to resolve stalled Pol II: transcription-coupled nuc...

Happy to share a new preprint from our lab, uncovering "spooky action at a distance" - for RNA Polymerase II:
www.biorxiv.org/content/10.6...

We’ve demonstrated Matchbox for demultiplexing long-read scRNA-seq data with 10X or SPLiT-seq barcodes; restranding RNA-seq reads; assessing CRISPR editing efficiency; and haplotyping repeat regions.

Matchbox is implemented in rust and available from github.com/jakob-schust....

@wehi-research.bsky.social

🚨Calling students! Join the Vervoort Lab @ WEHI for an Honours/PhD projects using CRISPR screens + genomics to reveal new regulators of gene expression. Info: www.wehi.edu.au/project/unco... 🧬

Science doesn’t need to be pretty and go according to plan; it just needs to lead to a discovery. If doesn’t have to be done alone or together with someone else; there just needs to be a discovery. It doesn’t need to happen fast or slow; just as long as there’s a discovery, then everybody is happy.

@mrclmb.bsky.social MRC LMB is looking for a new group leader in Chemical/Synthetic Biology. Come and join us in this fantastic institute! Core funding, amazing science all around you and great collaborative colleagues are just some of the highlights. Please share the news!

A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.

Follow addgene everone! A beautiful company built on ethics. Let's support them with a big following here. @addgene.bsky.social