Pedro Crevillén's Avatar

Pedro Crevillén

@crevillenlab

Group leader at @cbgpmadrid.bsky.social working on #epigenetics and #genomics in Arabidopsis and Brassica crops. Tweets science & related stuff in english and español.

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05.01.2026
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Latest posts by Pedro Crevillén @crevillenlab

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Heinrich-Mora & Feldman: "results suggest that mutation rate is systematically structured by chromatin state within functionally constrained genes and that evolutionary processes may act not only on expected mutation rate but also on its variability across loci."
arxiv.org/html/2603.03...

08.03.2026 07:41 👍 13 🔁 1 💬 0 📌 0
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Population epigenomics reveals epigenetic drivers of replicated evolution and missing heritability in soybean #research #PlantCommunications cell.com/molecular-pl...

03.03.2026 09:22 👍 1 🔁 2 💬 0 📌 0
Plant Epigenetics 2026 - Sciencesconf.org EPIPLANT 2026 will bring together the scientific community working across the broad fields of plant and algal epigenetics, chromatin dynamics, environmental responses and transgenerational inheritance. EPIPLANT 2026 is the biennial symposium of the CNRS Groupement de Recherche (GDR) EPIPLANT.

EPIPLANT conference

🌱 You like plants and epigenetics?
Explore mechanisms of chromatin regulation & epigenetics in Nantes, France!
🎤 Great speakers + oral & poster slots from selected abstracts.
22-24 June 2026
Abstract submission deadline: 24 April 2026.
epiplant-2026.sciencesconf.org

04.03.2026 15:54 👍 9 🔁 11 💬 0 📌 0
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A plant histone H3.3-specific amino acid safeguards the deposition of H3K36 methylation for proper development and stress responses Plant histone variant H3.3 uniquely carries T31 rather than the S31 found in animals. Li et al. demonstrate that T31 prevents plant-specific ATXR5/6-mediated H3K27me1 deposition, which would otherwise...

A plant #histone H3.3-specific #amino acid safeguards the deposition of H3K36 #methylation for proper #development and #stress responses

www.cell.com/developmenta...

#PlantScience #SciComm @cp-devcell.bsky.social @epigeneticspod.bsky.social @epigenometech.bsky.social @histone3.bsky.social

03.03.2026 23:52 👍 6 🔁 4 💬 0 📌 0
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Environmental exposure trains the immune system to dampen allergic responses Clean living conditions that lessen exposure to microorganisms are linked to an increase in allergies. Mouse data reveal how the environment affects allergic immune responses.

The most influential explanation of a recent surge in allergies is the hygiene hypothesis

go.nature.com/40woBkB

01.03.2026 09:58 👍 54 🔁 14 💬 2 📌 1

Arabidopsis EARLY FLOWERING 4 recruits EARLY FLOWERING 3 to the nucleus to facilitate gene repression https://www.biorxiv.org/content/10.64898/2025.12.12.688453v1

13.12.2025 06:01 👍 3 🔁 3 💬 0 📌 0
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Stress controls heterochromatin inheritance via histone H3 ubiquitylation - Nature A histone ubiquitin-dependent regulatory hub governs stimulus-dependent heterochromatin propagation, with important implications for understanding mechanisms governing rapid changes in the epigen...

Discussed @mrsantosny.bsky.social lit review: Stress controls heterochromatin inheritance via histone H3 ubiquitylation. www.nature.com/articles/s41...

25.02.2026 16:29 👍 0 🔁 2 💬 1 📌 0
Redirecting

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.

25.02.2026 16:01 👍 122 🔁 60 💬 9 📌 5
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JMJD2 regulates enhancer–promoter interactions via biomolecular condensate formation - Nature Genetics This study presents LoopID, which profiles proteins at targeted interacting enhancer–promoter (E-P) pairs, identifying the histone demethylase JMJD2 as a regulator of E-P interactions through biomolec...

➡️Noncatalytic roles of chromatin enzymes keep getting cooler: JMJD2 histone demethylases can regulate 3D enhancer–promoter communication via biomolecular condensates, ➿iLoop proteomics now let us map how #chromatin architecture rewires gene expression.
www.nature.com/articles/s41...

27.02.2026 09:32 👍 1 🔁 0 💬 0 📌 0
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Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...

🤩💪 Out now! 3D regulatory hubs in sex determination

With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social

1️⃣ METALoci – explore #3DGenome 🧬
2️⃣ Non-coding region controlling Fgf9 🧩
3️⃣ Meis genes = new key players 🌟

👉 rdcu.be/e5sm2

1/n Bluetorial 👇

24.02.2026 14:02 👍 59 🔁 26 💬 1 📌 2
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Chromatin dynamics shape aging across organs | Science Age-related chromatin remodeling includes shared and specific signatures across cell types, sex, and organs

Chromatin dynamics shape aging across organs | Science @Science.org

26.02.2026 22:05 👍 1 🔁 1 💬 0 📌 0
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Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers Abstract. Methylation of histone H3 at lysine 36 (H3K36me3) marks active chromatin. The mark is interpreted by epigenetic readers that assist transcription

Jayakrishnan, M., Havlova, M., Veverka, V., Regnard, C., Becker, P. B. (2025). Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers. Nucleic Acids Res, 53(6) academic.oup.com/nar/article/...

26.02.2026 23:20 👍 4 🔁 1 💬 0 📌 0

🌲 Final call - 3 days left!

Susan McEvoy is recruiting a postdoc in forest tree genomics and population genetics.

Work on genetic variation and local adaptation and become part of the #WIFORCE inititative!

📅 Deadline: 28 February

See details below and apply!

#PlantSciJob #Genomics #Postdoc

25.02.2026 08:59 👍 5 🔁 2 💬 0 📌 0

👏🏻APC have become completely outrageous — they’re off the charts, especially in top journals.

25.02.2026 09:28 👍 2 🔁 1 💬 1 📌 0

Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.

20.02.2026 02:51 👍 78 🔁 33 💬 0 📌 6
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The $100 whole human genome sequence finally reached!
www.sandiegouniontribune.com/2026/02/19/s...

20.02.2026 20:29 👍 258 🔁 77 💬 12 📌 11
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What does the new #TAIR12 Arabidopsis thaliana genome annotation look like?

bit.ly/3ZHtneT

#plantscience #plantbiology #Arabidopsis #cropscience #scisky 🧪

21.02.2026 04:59 👍 24 🔁 11 💬 0 📌 1
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🌼 A new study on early-diverging flowering plants sheds light on the evolution of plant reproduction

More information in our new article ⬇️
onlinelibrary.wiley.com/doi/10.1111/...

13.02.2026 08:19 👍 3 🔁 2 💬 0 📌 0
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PlantGPT: An Arabidopsis-Based Intelligent Agent that Answers Questions about Plant Functional Genomics
doi.org/10.1002/advs... via @Adv_Biology #PlantScience

10.02.2026 17:29 👍 2 🔁 1 💬 1 📌 0
Schematic summary of flowering outcomes in Arabis alpina mutants lacking FT and TSFL genes under different developmental stages and cold treatments.

Schematic summary of flowering outcomes in Arabis alpina mutants lacking FT and TSFL genes under different developmental stages and cold treatments.

CO-FT Regulation of flowering in Arabis alpina

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
by Sashidhar and Coupland

@WileyPlantSci #PlantScience BS @mpipz.bsky.social

10.02.2026 13:02 👍 7 🔁 3 💬 0 📌 0
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Now Lei Li, on behalf of @episeedlink.bsky.social students has presented "Junior Germination kit" in our internacional conference. A kit developed by them for using in school with children.

09.02.2026 11:00 👍 3 🔁 1 💬 0 📌 0
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Starting the @episeedlink.bsky.social internacional conference with the first session of talks "Seed to seedling translation"

09.02.2026 08:14 👍 5 🔁 2 💬 0 📌 0

This week in @science.org, a celebration of plant pangenomes. A pangenome analysis for massively polyploid sugarcane species, and one for Brassica rapa giving insight into subspeciation.

What's all the fuss about pangenomes? Pamela and Douglas Soltis explore this in an insightful Perspective(1/4)

06.02.2026 09:57 👍 31 🔁 17 💬 1 📌 0
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🧵(2/2) Right after that, we’ll join the @episeedlink.bsky.social international conference organised within the project, bringing together 150+ scientists from around the world to share ideas, discuss new findings, and connect across disciplines.🌱🧬🌾🧑‍🏫

A full week of science

Looking forward to it!

06.02.2026 22:34 👍 2 🔁 1 💬 0 📌 0

And publish in society owned journals like @theplantcell.bsky.social @theplantjournal.bsky.social Plant Biotechnology Journal, @jxbotany.bsky.social @newphyt.bsky.social @plantspeopleplanet.bsky.social and many others!

06.02.2026 17:40 👍 30 🔁 13 💬 0 📌 2
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Preocupación por las expectativas creadas por Barbacid sobre el cáncer de páncreas: “El anuncio se ha salido de madre” Varios centros de investigación están recibiendo una avalancha de peticiones tras un anuncio que, según muchos especialistas, ha sido mal comunicado: ni Barbacid ha encontrado la cura del cáncer de pá...

Ya para socios ‼️Preocupación por las expectativas creadas por Barbacid sobre el cáncer de páncreas: “El anuncio se ha salido de madre” www.eldiario.es/1_c5dac3?utm...

05.02.2026 21:39 👍 51 🔁 26 💬 6 📌 8

TiPS focus Issue highlighting a rapidly evolving field at the intersection of genome architecture, #epigenetics, and plant adaptation 🌱
www.cell.com/trends/plant...

05.02.2026 08:06 👍 7 🔁 1 💬 0 📌 0

🚨Given the scarcity of focused genetic studies in animals, it’s intriguing to see a recent study proposing H3K37ac as a stress-responsive #chromatin mark linked to salt-induced transcriptional activation in #rice. 🌾

04.02.2026 16:20 👍 2 🔁 1 💬 0 📌 0
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🥳 We are delighted to announce that more than 150 scientists will gather for our upcoming @episeedlink.bsky.social international conference¡

It’s inspiring to see such a vibrant community coming together to exchange ideas, strengthen collaborations, and shape the future of our research.🧬🌾🌱

30.01.2026 09:32 👍 4 🔁 2 💬 0 📌 1