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Sharona Gordon

@profsharona

Biophysics professor at University of Washington and founder of Below The Waterline and UW Allies. Lover of chocolate, labradoodles, transition metals, fluorescence, and membrane proteins.

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07.12.2024
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Latest posts by Sharona Gordon @profsharona

It is such a treat to be part of this team. Way to go Sophie, Suzanne, and Bill!

12.10.2025 04:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.

I am proud to be part of this new work with Pierce Eggan and Bill Zagotta, just published in eLife. Time-resolved tmFRET reveals ion channel energetics!
doi.org/10.7554/eLif...

20.08.2025 16:14 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

NIH funding REINSTATED! Thank you to @atg.wa.gov and other attorneys general and to Judge Young. This saves the career of a promising junior scientist. TY @jeremymberg.bsky.social for all your help interpreting these events.

03.07.2025 21:38 πŸ‘ 217 πŸ” 21 πŸ’¬ 1 πŸ“Œ 7
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Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation - Nature Communications Genetic code expansion (GCE) enables the incorporation of new amino acids into proteins. Here, authors demonstrate the rapid OrthoRep-driven evolution of aminoacyl-tRNA synthetases for GCE, increasing...

Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to Yuichi Furuhata, a true master bioengineer, on leading this excellent work! www.nature.com/articles/s41...

24.05.2025 15:02 πŸ‘ 34 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0

I am so sorry - for them and for you. Have been ousted from admin roles I know how sucky it feels. Anything that takes choice away from us hurts. My hope is the next chapter is even better.

10.04.2025 15:56 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Great news: NIH postbac program is recruiting again! If your grad school plans were affected by program cutbacks or admissions freezes this year I highly encourage you to apply, this could be a perfect opportunity. Please repost.

www.training.nih.gov/research-tra...

10.04.2025 01:22 πŸ‘ 208 πŸ” 196 πŸ’¬ 6 πŸ“Œ 1
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Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches β€œwith deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Published an op-ed for @cnn.com: β€œNobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

09.04.2025 11:30 πŸ‘ 898 πŸ” 490 πŸ’¬ 15 πŸ“Œ 25

The notice for NEI’s Advisory Council meeting on April 21 is now posted to the public inspection part of the Federal Register and is scheduled to be released tomorrow. Progress!

20.03.2025 18:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Jeremy, you are a real light to us in this time of darkness. Not understanding the system makes everything so much harder.

20.03.2025 00:11 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

My NEI proposal previously assigned to cancelled February Council round now says in Commons status page:
Advisory Council (AC)
Meeting Date: 04/21/2025
Meeting Time: 10:00.

Anyone know whether that could be part of expedited review or is NEI Council might really be meeting then?

20.03.2025 00:01 πŸ‘ 2 πŸ” 0 πŸ’¬ 2 πŸ“Œ 1

With twice as many grants to fund (from two study sections rounds), how will they get all the paperwork done to fund before end of fiscal year? Might they ask for JIT submissions early? I don’t usually get asked til after Council meets so the info is β€œfresh.” How can we help POs under such pressure?

19.03.2025 13:32 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Add me please!

13.03.2025 02:18 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

12.03.2025 20:47 πŸ‘ 2030 πŸ” 1144 πŸ’¬ 23 πŸ“Œ 72

What a great thread. Thank you!

09.03.2025 16:41 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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11 folks in the Gordon and Zagotta lab family at Seattle #StandUpForScience event. We joined at least five other labs from @uw-nbio.bsky.social. This PhD student and postdoc organized event gives me hope that we can #ResistTogether to make science the culture we aspire to.

08.03.2025 17:04 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Heading to #standupforscience rally in Seattle.

07.03.2025 19:22 πŸ‘ 31 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Great ideas! Thanks for the printable files!

03.03.2025 16:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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a man in a suit and tie is making a really ? face . ALT: a man in a suit and tie is making a really ? face .

Politically motivated counterfeiting?

02.03.2025 21:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

What ideas do ppl have for text to put on signs? #Seattle friends: bring your sign-making materials to my lab at 10 am for a sign-making party! We can then take light rail to the demo together.

02.03.2025 16:10 πŸ‘ 37 πŸ” 5 πŸ’¬ 8 πŸ“Œ 1
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a man in a green shirt is eating a sandwich with the words life on mars on the bottom right ALT: a man in a green shirt is eating a sandwich with the words life on mars on the bottom right
01.03.2025 22:03 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
FederalΒ AdministrationΒ Updates - UW Research Office of Research Communications: Update on the Federal Research Funding Landscape New MOD Categories for Tracking Executive Actions Update Regarding NIH Indirect Cost Policy and TRO...

From University of Washington β€œIt is simply not possible for departments or the university to cover the costs currently funded by federal awards… we cannot count on the state of Washington to backstop federal funding.”

www.washington.edu/research/ann...

01.03.2025 06:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

What does this mean? β€œwe are working toward strategies to preserve the breadth of high impact research at UW, particularly through shared infrastructure, to the greatest extent possible.” This is grim.

28.02.2025 15:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
University of Washington message

I understand that β€œIt is simply not possible for departments or the university to cover the costs currently funded by federal awards” means the UW won’t help us.

1/2

explore.uw.edu/index.php/em...

28.02.2025 15:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Stand UP for Science demonstration is happening Friday March 7th, 12-3 pm, in Seattle, at Mural Amphitheatre at Seattle Center
305 Harrison Street Seattle, WA 98109

26.02.2025 16:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I will be hosting sign making in my lab at 10 am on the 7th. All are welcome. Lease bring your own materials and DM me for more info.

26.02.2025 15:37 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Local Event Information Below are the state capitals and major cities (alphabetized by state) hosting official Stand Up for Science events. If your city is listed, a confirmed site leaderβ€”backed by our core teamβ€”is active…

So excited to see how quickly #StandUpForScience has grown from a single rally to rallies in 32 cities in 27 states and counting! Let's go! Thank you for your leadership @standupforscience.bsky.social!
They also opened up a donation page πŸ§ͺ
standupforscience2025.org/local-event-...

26.02.2025 14:53 πŸ‘ 60 πŸ” 19 πŸ’¬ 2 πŸ“Œ 3
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Trump cuts threaten a β€˜generation of scientists’ as many weigh leaving US President’s call to β€˜Make America Healthy Again’ has led to slashes in NIH funding – endangering jobs and vital research

β€œFor the last 75 yrs, the NIH has been the biggest funder of biomedical research in the world. Most advances in medicine were seeded by NIH funding. When we became scientists, we just bought into this system. This is how it works. β€” @tuthill.bsky.social 🧡

www.theguardian.com/us-news/2025...

19.02.2025 19:44 πŸ‘ 158 πŸ” 79 πŸ’¬ 5 πŸ“Œ 3

Trump's illegal NIH cuts mean cancer researchers would be laid off, sick kids going without treatment, and more. These cuts would be DEVASTATING for lifesaving research.

Some Republicans have said they agreeβ€”but they just blocked my amendment to reverse Trump's NIH cuts anyway.

21.02.2025 09:27 πŸ‘ 372 πŸ” 145 πŸ’¬ 31 πŸ“Œ 8

LAYOFFS WILL CONTINUE UNTIL MORALE IMPROVES!

22.02.2025 23:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Proud to be a constituent. Thanks Patty Murray! It makes me feel like all my emails are having the intended effect.

22.02.2025 03:45 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0