New research - Appendicectomy versus switching to a JAK inhibitor in inducing remission in patients with active ulcerative colitis after biologic therapy failure (COSTA): 1-year results of a multicentre, prospective, cohort study

www.thelancet.com/journals/lan...

#IBD #GastroSky #MedSky

Twin cities friends: I'll be speaking tomorrow at the Minnesota Center for Philosophy of Science on how AI disrupts the sometimes precarious balance of scientific incentives.

#HispanicHeritageMonth Spotlight: Monica A. Tincopa, MD

Dr. Tincopa is recognized for her professional achievements and her unwavering dedication to diversity, culturally informed care, and health equity in gastroenterology and hepatology.

➡️ bit.ly/acg-nhhm-25

The Farve surname is an altered form of the French occupational name Favre, meaning "blacksmith" or "ironworker"

Cooper Rush

Congratulations Bob!

Great article @bilalmohammadmd.bsky.social

I suspect, but cannot prove, that this effect is temporary. A ‘Termination Shock’. H/t to @nealstephenson.bsky.social

The gut's 'sixth sense' microbiome regulating eating behavior in real time, another new path for the gut-brain axis, "neurobiotic," in the mouse model
www.nature.com/articles/s41...

Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects Fecal microbiota transplants (FMTs) may not always effectively restore small bowel microbiota due to regional differences in gut environments, potentially causing unintended effects on metabolism and ...

The unintended consequences of a gut microbiome transplant
www.cell.com/cell/abstrac...

Our new clinical practice update in @aga-cgh.bsky.social offers insights on diagnosing and treating sclerosing mesenteritis — a rare, often asymptomatic condition of the bowel mesentery. 📄Read more here: gastro.org/news/expert-....

#GIsky

Overcoming the challenges of overtreating and undertreating inflammatory bowel disease Several therapeutic advances have been achieved over the past two decades for inflammatory bowel disease (IBD). The expanding therapeutic armamentarium and the increasingly ambitious treatment targets...

Today is #WorldIBDDay!

Some recent #IBD related highlights in the journal:

1) Overcoming the challenges of overtreating and undertreating inflammatory bowel disease
www.thelancet.com/journals/lan...

#gastrosky #ibdsky #medsky

Minneapolis VA’s CMS.gov rating. A perfect 5 stars, with national average being 3.

The Minneapolis VA Medical Center got it’s CMS rating today; based on mortality, safety of care, readmission, patient experience, and access. We are one of 2 (out of 19) Twin cities hospitals to get the highest 5-star rating. The VA is outstanding- but under threat.

My parasocial relationship with Ed Yong really helped me through the pandemic. Excellent journalist with a well-deserved Pulitzer.

My question-is polyethylene glycol an emulsifier as well?

The emulsifiers that are best to be avoided in foods
www.wsj.com/health/welln...
like polysorbate 80, xanthan gum, guar gum, carboxymethylcellulose

I keep forgetting you two did fellowship together. He also gave grand rounds at our VA on Friday. Great talk about c difficile and some of the really cool IBD work he’s doing with my partner Daphne Moutsoglu.

A concern about medical A.I. is that its reliance by physicians could lead to degradation of performance. Here is one such example of de-skilling with GI doctors and colonoscopy for detection of polyps (preprint) papers.ssrn.com/sol3/papers....

Georgia Nonprofit That Produces Life-Saving Food For Kids Has Federal Contract Cut An estimated 300,000 children globally are expected to lose access to a nutrient-dense peanut butter that’s specially formulated to treat severe acute malnutrition.

An estimated 300,000 children globally are expected to lose access to a nutrient-dense peanut butter that’s specially formulated to treat severe acute malnutrition.

Join ACG for the next Virtual Grand Rounds—

ACG Clinical Guideline: Focal Liver Lesions
Reena J. Salgia, MD

Thursday, February 27 at Noon & 8pm ET
➡️ gi.org/ACGVGR

A heart-shaped polyp is the best way to wish HAPPY VALENTINE'S DAY to the #ACGfamily!

With love and deep respect for all the #PolypSlayers

Quality #Colonoscopy detects precancerous polyps and can prevent #ColorectalCancer

#GastroSky #EndoscopySky #MedSky @amyoxentenkomd.bsky.social

Count me in!

NEW! Ergonomics for Endoscopy: Optimal Preparation, Performance, and Recovery

A comprehensive roadmap for navigating and implementing practical ergonomic interventions to ensure the health and safety of your team.

Order today ➡️ bit.ly/ergo-for-endo

Notable IBD publications in 2024 As 2024 draws to an end, several significant publications have advanced our understanding of inflammatory bowel disease (IBD) treatment.

As 2024 draws to an end, several significant publications have advanced our understanding of inflammatory bowel disease treatment. Key studies offer important insights and a few are worth highlighting...

...continue reading at --> substack.com/home/post/p-...

#IBDSky #GISky

Only problem is that my phone keeps trying to autocorrect it to liverpool.

Congratulations Bill!

IFX+AZA vs AZA in ASUC pts who responded to IV steroids (ACTIVE trial)

- n=64, bio-naive pts
- steroids stopped after d7 (combo arm), d14 (AZA arm)
- IFX dose escalation to 10mg/kg allowed
- no deaths or colectomy
- IFX/AZA had lower rates of "failure" by week 52

Practice changing?
#IBDSky #MedSky

In the #RedJournal

Tseng, et al., Bleeding Risk of Cold Versus Hot Snare Polypectomy for Pedunculated Colorectal Polyps Measuring 10 mm or Less: Subgroup Analysis of a Large RCT

📕 bit.ly/4eENCPo

#GastroSky #EndoscopySky #Gastroenterology

Medicine focuses a lot on the question “will this help my patient” but not on the question “when will it help my patient.” The latter becomes important as we age. We’ve developed a “time-to-benefit” tool on eprognosis.ucsf.edu to help answer this question. Here is a snapshot
#MedSky #FOAMed #meded