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Michelangelo Lassandro

@miclass

PhD student in Structural Biology at Human Technopole, Milan, Italy. Passionate about RNA related world.

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Latest posts by Michelangelo Lassandro @miclass

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

06.02.2026 11:20 πŸ‘ 84 πŸ” 29 πŸ’¬ 8 πŸ“Œ 3
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πŸ₯³Today at HT, we took the time to celebrate one another, recognising colleagues who have stood out for their contributions or positive attitude.

πŸ‘Congratulations to the winners: Roberto Zigiotto (Above & Beyond Award) and @giovannimaltinti.bsky.social (Good Vibes Award)!

22.01.2025 15:12 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...

Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...

A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work

03.01.2025 10:37 πŸ‘ 52 πŸ” 19 πŸ’¬ 4 πŸ“Œ 2

JOB ALERT!!! The National Facility for Structural Biology at @humantechnopole.bsky.social is HIRING!! BlueSky-less Andrea Graziadei is looking for a technician to join his Unit and push #structuralproteomics to new, uncharted territories!! 1/3

05.12.2024 09:23 πŸ‘ 9 πŸ” 11 πŸ’¬ 1 πŸ“Œ 1
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The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...

Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...

18.11.2024 11:06 πŸ‘ 87 πŸ” 28 πŸ’¬ 2 πŸ“Œ 2

Thank you! Can you also add @peronegaia.bsky.social ??

17.11.2024 15:37 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0