Andy C. H. Lee

Professor, Senior Lecturer/Lecturer and Lecturer posts - Glasgow City (GB) job with University of Glasgow | 12838283 University of Glasgow College of Medical, Veterinary and Life Sciences  School of Psychology & Neuroscience Professor in Cognitive Neuroscience/Psy...

We’re recruiting for 5 faculty positions in cognitive neuroscience, psychology & animal neuroscience!
Exciting science going on @UofG, Glasgow is an amazing and green city with the friendliest people, and you’ll have the stunning highlands on your doorstep!
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Hippocampal damage disrupts the latent decision-making processes underlying approach-avoidance conflict processing in humans How does the hippocampus support value-based decisions under motivational conflict? Through a mix of computational modelling approaches and behavioral studies in people with hippocampal damage, this s...

Our latest paper on hippocampal contributions to motivational conflict decision-making is now out: doi.org/10.1371/jour...
Thanks to Chris Butler and @gpdargyropoulos.bsky.social for the transatlantic collaboration.

Chemogenetic inhibition of ventral hippocampus CA1 (vCA1) to NAc shell projections. Left: Schematic diagram of inhibitory DREADDS (hM4Di-mCherry) or empty vector (GFP) transduction in vCA1 and cannula implantation in NAc shell via which CNO or saline was microinfused for pathway-specific inhibition. Right: Representative images of somatic transduction of hM4Di-mCherry or empty vector GFP in vCA1 (left) and axonal transport of the viral load in the NAc shell (right). Scale bar, 1 mm.

How do animals decide whether to approach or avoid objects or situations that have both +ve & -ve valence? This study shows that glutamatergic projections from vCA1 to NAc regulate these approach decisions in mice, especially re motivational conflict 🧪 @plosbiology.org plos.io/3WAWBej