In @JOrthopRes.bsky.social, the Christiansen Lab (UC Davis) reports sex differences in mice post-femur fracture:
๐ฆด Males show greater systemic bone loss & TNF-ฮฑ elevation
๐ช Females trend toward greater muscle loss in the injured limb
buff.ly/LfFQjGn
#ORSxDerby #ORSSMC
@ORSsociety.bsky.social
@kelseyhcollins.bsky.social and I are kicking off the USASP Annual Scientific Meeting with a trip to the iconic Bean! Excited to be in Chicago, present my work this afternoon at poster B28, and join the Pain & Aging SIG tonight! ๐
@usasp.bsky.social
Itโs out! Powerhouse team and a powerhouse paper with exciting and novel findings. Honored and proud to be part of this one - check it out! โฌ๏ธ๐
Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ
Thanks to @farsh-g.bsky.social for all of your support - @thehopefulscie1.bsky.social and all coauthors!
A sky blue tube rack contains a clear eppendorf tube. A teal gloved hand uses a dark blue lever to open the eppendorf tube with minimal force/strength.
#labdaptations alert๐จ! This tube opener is great for individuals with limited hand strength/mobility or tremors. I use it to keep my joints from hyperextending/dislocating, which helps to decrease pain.
Many congratulations to the newly elected chairs @thehopefulscie1.bsky.social , @jackbroberts.bsky.social for GRS Cartilage 2027.. Great to see the GRS is in safe hands..
Hey #CartilageGRS2025 trainees! Defending soon, looking for a postdoc, and/or want to live in beautiful San Francisco, CA? We're looking for motivated folks to solve complex puzzles involving systemic factors, fat, aging, the gut microbiome and MSK health. DMs open! @thehopefulscie1.bsky.social
Feeling incredibly honored to be elected as a GRS Co-Chair AND to receive a podium award! Grateful for this opportunity to present some of our recent findings throughout the week and to be surrounded by such inspiring work and scientists at this conference ๐
Excited for our workshop on interdisciplinary solutions to study mechanisms of musculoskeletal pain at #USASP2025 in Chicago, featuring talks from Nadeen Chahine, Hang Lin, Rachel Miller, and Allan Basbaum @usasp.bsky.social. #painresearch
Would love to see you there!
List of Stand Up for Science eventsโofficial events in red, solidarity events in blue.
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROMโ153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ โ๏ธโฌ๏ธ๐
Proud to be a scientist today and everyday. Science belongs to everyone and is for everyone โค๏ธ๐งฌ #StandUpForScience
A person in a mask holding a painting that says โhands off my transgenic miceโ
At @standupforscience.bsky.social and the signs are statistically significantly excellent
๐จ๐งช Weโve been talking to scientists at rallies today across the country in DC, Boston, Seattle, and NJ. Hereโs why scientists are โDismayed, depressed, disgustedโ and what theyโre doing about it
๐งต โคต๏ธ for more
#StandUpforScience #StandUpforScience2025
@nature.com
#ORS2025 was one of the books! Loved sharing my science, volunteering at #ORSOpenDoor, seeing old friends and making new ones โค๏ธ
See you next year in Charlotte, NC!
A picture of Meghan at the podium for her talk entitled โEarly Middle School Students are Highly Impressionable to Diversity-, General STEM-, and MSK Research-Related Awareness and Interestsโ during the ORS Annual Meeting.
Stellar presentation on student outcomes of the 2024 #ORSOpenDoor event by @mmcgeelawrence.bsky.social!
It was great to see how much the program has grown and thrived in its revival during her tenure as @orssociety.bsky.social Advocacy Council Chair.
Canโt wait to share 2025โs data with yโall!
Whenever you hear someone sneer about scientific research that seems useless to them โ โtheyโre studying the spit of lizards?!โ โ remind them thatโs exactly how we got Ozempic.
globalnews.ca/news/9793403...
๐๐ก๐๐ญ ๐๐ซ๐ "๐ข๐ง๐๐ข๐ซ๐๐๐ญ๐ฌ"? When I write a grant, I provide a budget of the estimated "direct" costs that it will take to complete the project. These direct costs include things like salaries (mine + my lab members), student tuition, lab supplies, computing, and specialized equipment. The "indirect" costs on NIH grants are added on top of this and they pay for things like building infrastructure, utilities (water, electricity, internet), and salaries of administrative support staff like people who help us submit the grants, safety personnel, and janitors. The description that NIH is subsidizing universities with indirects is false. These are costs that are essential to perform the research that the government has agreed to fund. Indirects are negotiated with the government ahead of time so these are mutually agreed upon numbers and can't be changed by universities (or the government) on a whim. ๐๐ก๐๐ญ ๐ข๐ฌ ๐ญ๐ก๐ ๐ข๐ฆ๐ฉ๐๐๐ญ ๐จ๐ ๐ฌ๐ฎ๐๐๐๐ง๐ฅ๐ฒ ๐ฅ๐จ๐ฐ๐๐ซ๐ข๐ง๐ ๐๐๐ ๐ข๐ง๐๐ข๐ซ๐๐๐ญ๐ฌ? For this, I think some numbers are helpful. If I write a $100,000 grant, my institution's indirect rate is 62.5% so the university submits a total budget of $162,500 to the NIH for the project (100k for me, 62.5k for indirect costs). The new 15% rate is supposed to be effective immediately and applied to current grants (where we already agreed on the costs) such that suddenly instead of $62,500, the NIH will only pay the university $15,000. This will simply not cover the costs of actually performing the proposed research. Remember, the government set these indirect cost numbers - they were negotiated with universities that had to prove how this money is spent and follow very strict rules about what it can be used for. Let me be clear: these changes will destroy biomedical research in the US. ๐๐ก๐ฒ ๐ฌ๐ก๐จ๐ฎ๐ฅ๐ ๐ฒ๐จ๐ฎ ๐๐๐ซ๐? Most people are not scientists, so why should they care about research? Universities are often among the top employers in their cities. Even โฆ
I am starting this morning by reaching outside of my science echo chamber (posting on facebook) to explain why the NIH matters and why the new indirect rate policy will be catastrophic to everyone
Another amazing talk at #ORS2025 from @carolynchlebek.bsky.social !
๐๐ผ๐๐ผ
It was so fun to collaborate and bring #metabolomics into this well designed study centering around the effects of #obesity and weight loss on bone ๐ฆด
Starting #ORS2025 with a phenomenal talk from @sadewill.bsky.social on how #aging and the immune system alter and magnify IVD in both males and females, and more so, how #pain fits into this complex relationship ๐๐ผ๐งฌ
Hey @orssociety.bsky.social members! Are you at #ors2025? The board needs your feedback on the strategic plan. Please visit the focus groups in person today and tomorrow, or DM me for the QR code to submit feedback online.
Your voice matters!
And thatโs a wrap on #ORSOpenDoor!๐๐๐
It was such a fun day for students, teachers, and volunteers. Huge thanks to our leaders @jasoncmarvin.bsky.social and Paula Hernandez, amazing volunteers, and @orssociety.bsky.social staff who made this event possible!
The students had excellent questions for our awesome panel. One student asked โwhat is one piece of advice you would give us as middle schoolers?โ We love Lanceโs great piece of advice!
โฌ๏ธ๐๐ผ
#ORSOpenDoor @orssociety.bsky.social
Next up is @sadewill.bsky.social teaching us about the #spine, the immune system, and her journey in #ortho. She even put us all to the test guessing the animal based off their #skeleton ๐ฆด๐ด๐
#ORSOpenDoor @orssociety.bsky.social
@jasoncmarvin.bsky.social is our first speaker at #ORSOpenDoor educating us on #orthopaedics and #biomedical engineering! Importantly, Jason discussed that it is the only discipline to teach #equality in degrees earned with #women earning half of the bachelors degrees! ๐
Your #ORSOpenDoor 2025 volunteers!
We are so excited to engage students and teachers in short career talks, a discussion panel, and hands on workshops - itโll be a fun day full of #stemoutreach! ๐๐งฌ๐ฆด @orssociety.bsky.social
Jason, Paula, and Paige at the ORS Open Door event standing in front of the banner.
Bright and early, weโre all ready in Phoenix for the 2025 #ORSOpenDoor event!
Excited to welcome over >120 middle school students for an immersive, hands-on day of presentations, workshops, and discussion related to musculoskeletal research ๐
#STEMOutreach @orssociety.bsky.social
It is almost time for #ORSOpenDoor! Volunteers have arrived, coffee is being served, and workshops are underway ๐
Follow along here and on Blue Sky to get all the updates today! @orssociety.bsky.social
๐ช๐ฌ Happening tomorrow! ORS Open Door 2025, Feb 7 at the University of Arizona.
We are excited to welcome Rogers Ranch STEM Academy students for career talks, a discussion panel with ORS members, and hands-on STEM workshops. Learn more: buff.ly/3VIyUjw
Synovial fibroblasts support vascular function in both health and inflammatory disease, HM Zlotnick, ORS 2025 talk.
Looking forward to seeing everyone at #ORS2025! I will be presenting my postdoctoral work in the 'Crosstalk among Musculoskeletal Tissues and Beyond' session. Sunday, 4:25 - 4:35 pm, West 301D.
@schmidtsciences.bsky.social @orssociety.bsky.social
Boarding my flight to #ORS2025! ๐โ๏ธ
Excited to be part of the RIG: Bridging Disciplines to Find Solutions for #Osteoarthritis on Saturday night! Plus, catch my work on Monday and research from the June & Collins labs and our collaborators throughout the weekend! โฌ๏ธโฌ๏ธ
