Trentini Lab

👩‍🔬 Today is International Day of Women and Girls in Science! Meet Romy Baier, PhD student in the @trentini-lab.bsky.social at the @unicologne.bsky.social

Very happy to share our new preprint on #Golgi #PQC Very grateful to be working at the @hellerschmiedlab.bsky.social and with all the co-authors and colleagues. Special thanks to Sofia- without her, this story wouldn't have #unfolded as it did @unidue-zmb.bsky.social @imprs-lm.bsky.social

Congratulations Nisha! I'm looking forward to hearing all about your exciting research.

We had a fantastic time at the Ribo-Seq workshop in Bonn. Thanks so much, Kathrin @katleppek.bsky.social and Ranen, for organizing! We learned a lot, and we're excited to use Ribo-Seq in future projects.

List of talks at the 10th Rhineland RNA Club meeting on 14 November @MPI Age in Cologne. Generously supported by the RNA Society, Lexogen, siTOOLs, Immagina Biotechnology, Twist Bioscience, and NEB.

We would like to invite all Rhineland RNA enthusiasts to attend our next series of in-person talks, featuring local and invited speakers. Highlights include the external talks by Didier Stainier, Simon Bekker-Jensen and Ranen Aviner. Please, register: tinyurl.com/RhinelandRNA

CECAD: Our Scientific Mission YouTube video by CECAD Cologne

⏰🔬⏳What if we could prevent age-related diseases before they even start? At #CECAD Cologne, that’s exactly our #mission! In this new video, Prof. Dr. Carien Niessen shares our vision uncovering the biology of #aging to improve #health.

#HealthyAging @unicologne.bsky.social

youtu.be/9ALNLpG3oYc

🚨 Speaker Alert! 🚨
We’re thrilled to announce the next #CRC1678 Seminar featuring @christinemayr.bsky.social !
Join us to dive into the fascinating role of mRNA 3′UTRs in chaperoning intrinsically disordered regions to regulate protein activity.
📅 September 16
📍 CECAD Lecture Hall
⏰ 2:00 PM

I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.

🚨Check out this brand new publication from the lab of our CRC 1678 project leader @thevilchezlab.bsky.social about how C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules! Congrationlations to this achievement!🥳

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells Pluripotent stem cells (SCs) rely on metabolic rewiring to regulate self-renewal and differentiation. The hexosamine biosynthetic pathway (HBP) integrates multiple metabolic inputs to produce uridine ...

🎉 We’re excited to share our very first preprint!! 🎉
"Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells"
👉 doi.org/10.1101/2025...

#FirstPreprint #StemCells #Metabolism #Epigenetics #AcetylCoA #HBP #Pluripotency #NewScience

Principles of ribosome-associated protein quality control during the synthesis of CFTR Prolonged translational arrests caused by defective mRNAs activate the ribosome-associated protein quality control (RQC) pathway, which marks harmful incomplete proteins for degradation. Multipass tra...

🚨 Happy to share our first pre-print 🎉 on the causes of ribosome-associated degradation of CFTR and other transmembrane proteins.
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...

Cool work! Congrats Doris and team!

Very happy to see our contribution to a better understanding of Hsp70/90 #chaperones online! Congrats and a big thank you to all co-authors, collaborators and reviewers! #proteostasis @poepsel-lab.bsky.social @crc1430.bsky.social @unidue-zmb.bsky.social

Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity

Freshly launched! 🚀 Check out the new CRC 1678 website 🌐
👉 crc1678.uni-koeln.de

New from our lab @crick.ac.uk, in collaboration with the Enchev and Bukau labs.
By studying a protein that is difficult to fold, we discover fascinating new mechanisms by which the ribosome supports protein biogenesis.
www.biorxiv.org/content/10.1...

Congratulations to PhD student Tom Eisenack for winning a poster prize at the #ubfriends2025 symposium! Many thanks to the organizers for putting together such a fantastic meeting!

Congratulations Marcin and partners!

I really enjoyed your talk! Thanks for visiting us and sharing the very cool work on protein quality control at the Golgi.

This week, the @crc1678 kick-off retreat brought all the project leaders together! 🚀 A fantastic opportunity to dive into projects, spark collaborations, and lay the groundwork for an exciting journey ahead. On our way to innovation, teamwork and impactful discoveries! 💡👩‍🔬🧑‍🔬 #Research #Collaboration