Paul Marcogliese, PhD (he/him)

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts Chen et al. describe how TMX2, a thioredoxin-related transmembrane protein, moderates oxidative conditions at the endoplasmic reticulum-mitochondria contact site (ERMCS). This allows TMX2 to limit mit...

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts: Cell Reports www.cell.com/cell-reports...

Figures and data in A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila A large collection of functional EGFP tagged proteins derived from MiMIC insertions allows examination of protein expression in unfixed tissues and efficient tissue specific reversible knock down of p...

people seem to talk about 3 factors.

1. dynamics of GAL4 itself, life cycle / lifespan changes with temp
2. thermodynamics of the GAL4
3. A few cite HS promoters on the UAS side.

There could be other contributors

Figure 4 supplement 1 shows the effect on protein

elifesciences.org/articles/053...

Congrats Danielle!!!

Excess Wnt in neurological disease url:https://portlandpress.com/biochemj/article/482/10/BCJ20240265/236054/Excess-Wnt-in-neurological-disease

National Letter Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...

Over 1300 signatures and climbing.

docs.google.com/document/d/1...

National Letter Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...

It is so amazing to see that over 800 people so far have signed on to this open letter from Canadian researchers to the federal party leaders! So many incredible people who do such amazing research docs.google.com/document/d/1...

Open letter to federal leaders from Manitoba researchers gets support from hundreds of Canadian academics | CBC News An open letter penned by a group of Manitoba researchers has garnered support from hundreds of other scientists and academics across the country, sounding the alarm about the effects of research cuts ...

www.cbc.ca/news/canada/...

National Letter Open Letter from Canadian Researchers to the Federal party leaders Click here to sign this letter See who has signed - version française se trouve à page 3 - Dear Party Leaders We, the undersigne...

Dear Canadian researchers, faculty, RAs, PDFs and grad students, this letter is for the federal party leaders asking them to defend and expand Canadian research sovereignty with a historic investment in science, please sign and share
docs.google.com/document/d/1...

Congrats!!!!

Canada should double the entire research budget for base level funding (project, discovery, insight) and trainee fellowships. @markcarney2025.bsky.social if you win today - research needs to be part of the platform. The economics work. Research investments pay for themselves (and then some).