Thackery Brown's Avatar

Thackery Brown

@thackerybrown

Cognitive Neuroscientist interested in memory, emotion, and decision-making and their intersection in spatial navigation https://maplab.gatech.edu/ navsci.gatech.edu

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22.01.2025
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Latest posts by Thackery Brown @thackerybrown

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Egocentric Spatial Memory Deficit in Amnestic Mild Cognitive Impairment Revealed Through Virtual Reality: Cross-Sectional Study Background: Spatial navigation relies on egocentric and allocentric frames of reference, with the latter critically impaired in Alzheimer disease (AD) due to hippocampal involvement. Recent evidence s...

Check out this fascinating article aging.jmir.org/2026/1/e79224

02.03.2026 01:50 πŸ‘ 10 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Place cells in CA1 lack topographical organization of firing locations | PNAS Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. πŸ§ πŸ—ΊοΈ Out now in @pnas.orgΒ www.pnas.org/doi/10.1073/...

19.02.2026 11:53 πŸ‘ 149 πŸ” 43 πŸ’¬ 4 πŸ“Œ 8
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Excited for @crane-navsci.bsky.social conference!
Our keynote speaker is @russellepstein.bsky.social, with a panel @noranewcombe.bsky.social @aliprestonphd.bsky.social and Daniel Dilks. This is a super intimate and interdisciplinary conference focused on spatial cognition.

Submissions are open!

16.02.2026 17:42 πŸ‘ 15 πŸ” 4 πŸ’¬ 1 πŸ“Œ 3

Please share - we hope to see you and your work in May!

12.02.2026 12:52 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Harmonized Protocol for Subfield Segmentation in the Hippocampal Body on High‐Resolution InΒ Vivo MRI From the Hippocampal Subfields Group (HSG) Hippocampal subfields differentially develop and age, and they vary in vulnerability to neurodegenerative diseases. Innovation in high-resolution imaging has accelerated clinical research on human hi....

The Hippocampal Subfields Group standardized+reliable protocol for defining hippocampal body subfields in MR images is published! This is the result of a massive international effort. Check it out and keep your eyes peeled for training events from our raters

onlinelibrary.wiley.com/doi/10.1002/...

05.02.2026 00:20 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Is it the definition of madness that I keep pouring countless hours into developing NIH proposals?

03.02.2026 22:10 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion β€” without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)

The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See πŸ“Ή in post 4/6 and preprint here πŸ‘‰
www.biorxiv.org/content/10.6...
🧡(1/6)

28.01.2026 10:03 πŸ‘ 183 πŸ” 62 πŸ’¬ 4 πŸ“Œ 10
Redirecting

Planning + navigating novel shortcuts differently tax vmPFC subregions

Shortcuts differing more from prior experience are more demanding

Posterior vmPFC functions more closely resemble hippocampus and event separation

@crane-navsci.bsky.social
@paulinamaxim.bsky.social

doi.org/10.1016/j.ne...

24.01.2026 14:36 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Kind of awesome belated Christmas gift from my mom

20.01.2026 23:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Wayne State University’s vice president for research & innovation announces new leader of the Institute of Gerontology

research.wayne.edu/news/wayne-s...

23.10.2025 00:44 πŸ‘ 11 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

🚨 Our latest preprint:

A new tool to provide assessments of experience of the built environment: the NDIX.

This has been now deployed in 4 studies, being written up.

Here is the methods preprint with a starcast of co-authors:

13.10.2025 09:03 πŸ‘ 4 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

The CRaNE center is now on Bluesky, with a new collab pub to share! Please follow for news of our members' science and our conferences and workshops!

@tammyish.bsky.social @shiyiliang.bsky.social @paulinamaxim.bsky.social @gtsciences.bsky.social @gt-neuro.bsky.social

10.10.2025 23:14 πŸ‘ 11 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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In today's episode of "my colleagues are awesome" @tammyish.bsky.social

02.10.2025 20:57 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Going to ANFA? Check out Simin's talk on our research into how the built environment shapes memory through curiosity. I'm proud of her for the special recognition she's received!

16.09.2025 11:31 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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It was an honor to get to present at the NTNU last week. And for those who are curious, Trondheim is a gorgeous city

15.09.2025 22:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Music Scaffolds Visual Statistical Sequence Learning Through Network-Level Reorganization in the Brain Statistical learningβ€”the ability to extract patterns from noisy continuous experiencesβ€”is fundamental to human cognition. Yet, how contextual factors shape this process remains poorly understood. Musi...

🧠🎡 OUR NEW PREPRINT: Familiar melodies hijack your brain's learning networksβ€”literally rewiring visual sequence processing from struggle mode to flow state.

@thackerybrown.bsky.social

πŸ”— www.biorxiv.org/content/10.1...

12.08.2025 19:53 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Abby enjoys grant writing more than me

23.05.2025 21:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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With another round of amazing seniors departing GT, they bring more tears to my eyes

24.04.2025 20:02 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Word on the street is there were 20,000 people on the ground in Atlanta today

06.04.2025 00:03 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

#cns2025 come see our posters from the MAP Lab!

Sunday 5-7pm, C4 - Yiren Ren presents one of her recent studies on how music context signals influence event memory segmentation and learning

Tuesday 8-10am, F2 - Paulina Maxim presents data from young+older adult navigators on shortcut navigation

30.03.2025 02:00 πŸ‘ 9 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Following...

22.03.2025 16:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

New article out! It's a collaboration in the journal Music Perception where we show that metric emphasis influences what listens hear as tonic/stable in pop music loops:
static1.squarespace.com/static/54518...

15.03.2025 00:45 πŸ‘ 24 πŸ” 4 πŸ’¬ 5 πŸ“Œ 0

Excellent work led by @green951.bsky.social showing how human retrosplenial cortex integrates landmarks and self-motion cues during spatial navigation!

10.03.2025 09:33 πŸ‘ 7 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Fortitude

10.03.2025 00:48 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Great opportunity to work with a legendary mentor

08.03.2025 16:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The official link to apply for the postdoc position in my lab is live. Please pass it along! utaustin.wd1.myworkdayjobs.com/UTstaff/job/...

08.03.2025 15:10 πŸ‘ 8 πŸ” 10 πŸ’¬ 2 πŸ“Œ 2

Exactly - this is a very harmful stance taken. My job would be impossible without the whole team

08.03.2025 16:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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AR and EEG are fan favorites

08.03.2025 15:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Our 3 newest centers, CRaNE, CHART, and CoCo are a smash hit at the STEAM outreach event! Who knew science was cool!? @gtresearchnews.bsky.social @gt-neuro.bsky.social

08.03.2025 15:38 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Does that mean the registry is back open or is it wishful thinking on our brave admins’ parts?

02.03.2025 22:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0