Expansion microscopy physically enlarges tissue to bypass the diffraction limit. Dr. Sven Truckenbrodt explains how chemistry solves a physics problem in #neuroscience and #lightmicroscopy.
Check out the full episode here: youtu.be/a4qpFpjnOX4
Expansion microscopy physically enlarges tissue to bypass the diffraction limit. Dr. Sven Truckenbrodt explains how chemistry solves a physics problem in #neuroscience and #lightmicroscopy.
Check out the full episode here: youtu.be/a4qpFpjnOX4
Mapping the brain requires slicing tissue into thousands of sections and reconstructing it piece by piece. π§ Dr. Sven Truckenbrodt explains why data reconstruction is a major bottleneck in #connectomics.
Check out the full episode here: youtu.be/a4qpFpjnOX4
What does #connectomics actually give us? π§ It doesnβt explain behavior by itself but it provides the structural blueprint of neural circuits. Check out our latest episode for more on #connectomics and #brainresearch.
Check out the full episode here: youtu.be/a4qpFpjnOX4
How small is a synapse? At just nanometers scale, these tiny structures define brain connectivity. π§ Dr. Sven Truckenbrodt explains why synapse size matters for #neuroscience and #connectomics. Subscribe for more cutting-edge science!
Registration is open for #Neurizons2026 (19β22 May, GΓΆttingen)!
Check the details & register: www.neurizons.uni-goettingen.de/neurizons-20...
Please share this conference information to help us reach more people.
π¨NEW EPISODEπ¨
How do we map the #brain at molecular resolution?
@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.
πLink to the video: youtu.be/a4qpFpjnOX4
In our latest episode, Prof. Sauer explains how metabolic labelling introduces modified sugar precursors into cellular pathways, enabling fluorescent tagging of glycans and cell-surface structures for fluorescence imaging and quantitative analysis.
Watch the full episode here: youtu.be/8cXV9J5NJQQ
Prof. Markus Sauer discusses funding pressure, short-term contracts, and structural problems in academia, and how they shape scientific careers. #Academia #ResearchFunding
π Link to the video: youtu.be/8EHLKFByvvw
In super-resolution microscopy, labelling is key: unnatural amino acids enable precise, site-specific fluorophore attachment. Watch the full episode to learn how advances in #microscopy are reshaping our understanding of cellular structure.
youtu.be/8cXV9J5NJQQ
#Antibodies are often too bulky to reach every target in dense clusters, leading to incomplete labeling. #expansionmicroscopy solves this by physically separating proteins, which facilitates efficient labeling and reveals protein complexes.
Watch the full episode here: youtu.be/8cXV9J5NJQQ
Seeing the presynapse at the nanometer scale with super-resolution microscopes.
Watch our latest episode to learn about how modern #microscopy reveals the inner architecture of cells here: youtu.be/8cXV9J5NJQQ
Prof. Markus Sauer @sauerlab.bsky.social explains the physical and chemical origins of #photobleaching; Repeated excitation drives #fluorescent dyes into reactive states where interactions with oxygen destroy their ability to emit light.
Watch the full episode here: youtu.be/8cXV9J5NJQQ
How can individual #molecules be imaged with nanometer precision? Prof. Sauer from @uni-wuerzburg.de explains the idea behind single-molecule localization microscopy, and how #superresolution changed #microscopy.
youtu.be/8cXV9J5NJQQ
#SuperResolution #SciencePodcast
π¨NEW EPISODEπ¨
How do you see inside the cellular world with a nanometer precision? Watch our new episode with Prof. Markus Sauer @sauer-lab.bsky.social on super-resolution microscopy, dSTORM, and expansion microscopy.
πLink to the video: youtu.be/8cXV9J5NJQQ
Can exercise help prevent #ParkinsonsDisease? πββοΈ Prof. Randy Schekman explains how physical activity may support #brainhealth and resilience.
Watch the full episode here: youtu.be/G1FNf2LBPBo?...
Prof. Randy Schekman explains that Sergey Brin funds research without dictating how the money is spent, choosing instead to trust #scientists to manage #research decisions.
Watch the full episode here: youtu.be/G1FNf2LBPBo?...
How do billionaires support #science? Prof. Randy Schekman explains how private #funding has shaped large-scale #ParkinsonsDisease research efforts.
Watch the full episode here: youtu.be/G1FNf2LBPBo?...
What do we really know about #ParkinsonsDisease? Prof. Randy Schekman explains what science understands so far, and what remains unresolved.
Watch the full episode here: youtu.be/G1FNf2LBPBo?...
Why are extracellular vesicles so important? Prof. Randy Schekman explains that they carry key information about the cellβs internal state, with major implications for #diagnostics and #cellbiology.
Watch the full episode here: youtu.be/G1FNf2LBPBo?...
π¨NEW EPISODEπ¨
Nobel Laureate Randy Schekman joins Neuroscience and Beyond to explore how cells transport information, why extracellular vesicles matter, and what science can -and cannot yet- do about Parkinson's.
Full episode is out now: youtu.be/G1FNf2LBPBo
Alzheimerβs progresses like a relay race, moving from amyloid to inflammation to tau, with each step influencing the next. π§
Donβt miss our episode on the neurobiology of Alzheimerβs and the immune brain with Prof. Heneka from @uni.lu.
Watch the full episode here: youtu.be/EI_l91M9DE4?...
Knowing the genes behind a disease doesnβt guarantee a cure. It helps us understand risk and mechanisms, but translating this knowledge into effective therapies is not always straightforward.
Donβt miss our episode on the #neurobiology of #Alzheimerβs with Prof. Heneka here: youtu.be/EI_l91M9DE4?...
How do scientists study Alzheimerβs? By climbing a biological ladder - from molecules to human brain tissue - to trace the disease step by step. #Neuroscience #Alzheimers
Watch the full episode with Prof. Heneka here: youtu.be/EI_l91M9DE4?...
Varicella vaccination may reduce the risk of Alzheimerβs disease by about 20%.
Prof. Heneka from @uni.lu explains why #viral #infections - and our #immune response to them - may play a much bigger role in #Alzheimer's than previously thought.
Watch the full episode here: youtu.be/EI_l91M9DE4?...
Why canβt we personalize Alzheimerβs treatment the way we do in cancer treatment therapies? Prof. Heneka from @uni.lu explains the fundamental challenge.
Watch the full episode here: youtu.be/EI_l91M9DE4?...
#Alzheimers #Genomics
Can Alzheimerβs disease be prevented?
Research shows we can take meaningful steps today to lower our risk. Professor Michael Heneka from @uni.lu explains why prevention may be our most powerful tool until better treatments arrive.
Watch the full episode here: youtu.be/EI_l91M9DE4?...
Prof. Heneka from @uni.lu explains why early diagnosis of Alzheimerβs Disease is still one of neuroscienceβs biggest challenges.
Watch the full episode here: youtu.be/EI_l91M9DE4?...
#AlzheimersAwareness #EarlyDetection #DementiaResearch #BrainHealth
What Is Noise Beyond Decibels?
π₯ Watch Episode #30 with Chris Berdik @cberdik.bsky.social to explore how #noise shapes our #health, #focus, and #wellbeing in a noisy world.
Watch the full episode on this link: youtu.be/A5HZSU03qIM?...
How neurons make the brain special
π₯ Watch Episode #29 with Prof. Nikolay Kukushkin @niko-kukushkin.bsky.social to explore how #Neurons and other body cells store #Memory.
Watch the full episode on this link: youtu.be/x4dvE3uawyw?...
How the Amygdala Shapes Personal Space and Social Behavior
π₯ Watch Episode #28 with @raymundobaez.bsky.social to learn about #AmygdalaFunction, #SocialNeuroscience, #PrimateResearch, #GameTheory, #EmotionProcessing and more!
Watch the full episode on this link: youtu.be/AFb4pQJC9zo?...