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ICR-CTSU

@icr-ctsu

Clinical Trials and Statistics Unit @icr.ac.uk‬ Translating cutting-edge science into quality clinical trials to transform cancer care. www.icr.ac.uk/ctsu

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04.01.2024
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Latest posts by ICR-CTSU @icr-ctsu

DISTINCT project

Find out more about the DISTINCT project and how to register for the pilot here:
www.icr.ac.uk/research-and...
🧪
@ukcrc-ctu.org.uk

11.03.2026 10:47 👍 0 🔁 0 💬 0 📌 0

The work was done in collaboration with @qmul.bsky.social
and the question set is available to other non-commercial UK researchers to use in their projects as part of a pilot study. Feedback from the pilot will be used to improve the questions in future.

11.03.2026 10:45 👍 0 🔁 0 💬 1 📌 0
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Establishing a set of acceptable demographic questions for use in health research through public consultation - Research Involvement and Engagement Background The importance of inclusivity in health care and health research is increasingly recognised in the UK. However, there are currently no UK standards for collecting self-reported demographic ...

We recently published a paper about developing a demographic question set for research participants. We worked with patients and members of the public to agree an acceptable set of questions we can ask our participants.
link.springer.com/article/10.1...

11.03.2026 10:28 👍 1 🔁 0 💬 1 📌 0

Our former director, Professor Judith Bliss, will be speaking at this webinar on 17th March to celebrate International Women's Day #IWD2026

See below for details on how to register.

04.03.2026 11:40 👍 2 🔁 0 💬 1 📌 0
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Could expanding SBRT to pelvic lymph nodes improve outcomes for men with high-risk #ProstateCancer?

@profemmahall.bsky.social and Dr Angela Pathmanathan @icr.ac.uk, funded by Prostate Cancer UK, detail their trial approach in ctRO.

Grab a ☕ and read: www.ctro.science/article/S240...

03.03.2026 17:15 👍 3 🔁 2 💬 0 📌 0

Tomorrow, members of our #sustainability working group will be presenting as part of this seminar on the #EnvironmentalImpact of #ClinicalTrials.
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03.03.2026 16:41 👍 6 🔁 1 💬 2 📌 0

Thank you to all the participants and hospitals that took part in the CHHiP trial and provided samples for this project.

03.03.2026 13:56 👍 0 🔁 0 💬 0 📌 0

The marker was associated with recurrence and improved prediction of recurrence compared to other risk classifications currently used in clinic.

03.03.2026 13:56 👍 0 🔁 0 💬 1 📌 0

This study used data and samples from the CHHiP study and looked at testing whether a previously developed marker which classes patients as having high, intermediate or low risk of their #ProstateCancer coming back was associated with clinical outcomes.

03.03.2026 13:56 👍 0 🔁 0 💬 1 📌 0

Last week Dr Anna Wilkins presented "External validation of a digital pathology-based multimodal artificial intelligence (MMAI)-derived prognostic biomarker in the randomised phase III CHHiP trial" at the GU-ASCO conference.

03.03.2026 13:56 👍 2 🔁 0 💬 1 📌 0
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PACE-NODES: A phase III randomised trial of 5 fraction prostate stereotactic body radiotherapy (SBRT) versus 5 fraction prostate and pelvic nodal SBRT PACE-NODES is a phase III randomised controlled trial for patients with high risk localised prostate cancer, planned for radical radiotherapy with at …

The PACE-NODES protocol paper has been published in Clinical and Translational Radiation Oncology.
The #ClinicalTrial is comparing treating localised #ProstateCancer patients with SBRT over 5 days to the prostate alone or both the prostate and pelvis.
www.sciencedirect.com/science/arti...

27.02.2026 15:21 👍 2 🔁 2 💬 0 📌 0
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Data Curator/Engineer in Sutton | The Institute of Cancer Research View details and apply for this Data Curator/Engineer vacancy in Sutton. Salary : Salary range £39,805 - £41,900 per annum. Commencement on the salary range is subject to comparable skills a...

We are looking for a new Data Curator/Engineer.
For more information on the role and how to apply, follow the link below. #ResearchJobs 🧪
jobs.icr.ac.uk/vacancies/14...

26.02.2026 15:54 👍 2 🔁 2 💬 0 📌 0

It was an honour to represent @icr-ctsu.bsky.social at this event. Our collaboration with the ICR’s Division of Radiotherapy & Imaging has been a cornerstone of our trials portfolio for many years and we are proud of our contribution to the radiotherapy research recognised through this award.

25.02.2026 17:23 👍 5 🔁 1 💬 0 📌 0
ICR-CTSU clinical trials

Last week, the FAST-Forward Boost trial completed recruitment to the Early Side Effects Substudy with 345 patients randomised.

The study will now be transitioning to the main trial part of the study with a target of 4,830 patients.

You can read more about the trial here: www.icr.ac.uk/ff-boost

11.02.2026 15:12 👍 5 🔁 1 💬 0 📌 0
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Today is #WorldCancerDay.

This week we’re highlighting impactful work from Registered CTUs.

The @icr-ctsu.bsky.social IMPORT HIGH trial showed that treatment times for radiotherapy could be reduced for some early breast cancer patients.

🔗 tinyurl.com/y76mwfj8

#UKCTUNetwork #UnitedByUnique

04.02.2026 14:00 👍 2 🔁 1 💬 0 📌 0
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Study sets out clear recommendations for patient-reported outcomes in early cancer drug trials Study sets out clear recommendations for patient-reported outcomes in early cancer drug trials

4 February is #WorldCancerDay.

This week we’re highlighting impactful work from Registered CTUs, starting with this ICR-CTSU project setting out recommendations for patient‑reported outcomes in early cancer drug trials: tinyurl.com/35p76f3u

#UKCTUNetwork #UnitedByUnique @icr-ctsu.bsky.social

03.02.2026 13:47 👍 3 🔁 1 💬 0 📌 0
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New research introduces the first practical guidance on how patients’ own assessments of how tolerable they find treatments (patient-reported outcomes) can be used more effectively to inform and design early-stage cancer drug trials.

A thread 🧵⬇️

27.01.2026 15:28 👍 7 🔁 2 💬 1 📌 0

➡️ Please note, anyone who has chosen not to allow their NHS health data to be used for research will not be included in the data provided by NHS England. For more information visit the NHS website.

26.01.2026 17:05 👍 1 🔁 0 💬 0 📌 0
INTERACT

To find out more, including how to opt out from your information being shared with NHS England if you took part in one of our trials, head to:
www.icr.ac.uk/interact

26.01.2026 17:04 👍 1 🔁 0 💬 1 📌 0
INTERACT

To do this, we will send NHS England information about our trial participants (NHS number and date of birth). NHS England will use this to note which patients took part in our trials. We will not be able to identify anyone from the data we receive.

26.01.2026 17:04 👍 1 🔁 0 💬 1 📌 0

📢 We are doing a study called INTERACT to find out whether any groups of people have been less likely to take part in cancer studies in the UK.

We'll use routine data collected by NHS England to see if there are any differences between those who joined our clinical trials and those who did not.

26.01.2026 17:03 👍 3 🔁 1 💬 1 📌 0
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International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: OPTIMISE-ROR - PubMed This foundational guidance outlines key PRO research objectives in DFOTs. By facilitating the systematic integration of PROs, this guidance supports the utilization of patient-centered evidence for the tolerability and efficacy assessment of therapies to inform dose escalation, optimization, and reg …

Delighted to share OPTIMISE-ROR – recommendations to help embed patient-reported outcomes (PROs) more meaningfully in dose-finding oncology trials. It sets out core PRO objectives to support tolerability assessment, dose selection, and PRO strategy for subsequent studies. tinyurl.com/45thervu.

24.01.2026 14:45 👍 5 🔁 3 💬 1 📌 0
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UK real-world evidence on pembrolizumab and neoadjuvant chemotherapy for early-stage triple-negative breast cancer The KEYNOTE-522 trial showed that use of pembrolizumab-chemotherapy for stage 2-3 triple-negative breast cancer improved pathological complete respons…

Proud to have contributed to this paper, looking at real world evidence on the efficacy and safety of pembrolizumab in patients with early triple negative #BreastCancer

www.sciencedirect.com/science/arti...

22.01.2026 08:52 👍 4 🔁 1 💬 0 📌 0

At 4:05 this afternoon you can hear updates on the HER2 RADiCAL and FAST-FORWARD BOOST trials in the #ClinicalTrials session. One of our lead statisticians Lucy Kilburn will also be talking about enhancing trials using routine data linkage in this session.

19.01.2026 08:56 👍 0 🔁 0 💬 0 📌 0

We are looking forward to attending UKIBCS this morning and learning about recent advances in #BreastCancer
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19.01.2026 08:56 👍 2 🔁 0 💬 1 📌 0
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We're looking for people with experience of cancer who would like to share their thoughts and opinions with us to help design and deliver research at the ICR.

If you interested in helping research at the ICR, please fill out the registration form.
forms.office.com/e/YQ0SbaJ1ix
🧪 #Research

16.01.2026 16:51 👍 3 🔁 3 💬 0 📌 0
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Research Group Leader, ICR Clinical Trials and Statistics Unit (ICR-CTSU) in Sutton | The Institute of Cancer Research View details and apply for this Research Group Leader, ICR Clinical Trials and Statistics Unit (ICR-CTSU) vacancy in Sutton. Salary: £66,092 - £86,908 Appointments will b...

We are currently seeking an experienced statistician/biostatistician with a strong research interest in clinical trials methodology to join our team as a Research Group Leader.

You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/12...

🧪 #ResearchJobs #Statistics

16.01.2026 16:26 👍 4 🔁 4 💬 0 📌 0
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Senior Statistician / Principal Statistician in Sutton | The Institute of Cancer Research View details and apply for this Senior Statistician / Principal Statistician vacancy in Sutton. Salary : Senior Statistician: £47,634 - £52,324 Principal Statistician: £49,9...

We are currently looking for a new Senior Statistician/ Principal Statistician to join our team.

You can find more details, including how to apply, here:
jobs.icr.ac.uk/vacancies/14...

🧪 #ResearchJobs

14.01.2026 17:58 👍 2 🔁 3 💬 0 📌 0
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Senior Trial Manager in Sutton | The Institute of Cancer Research View details and apply for this Senior Trial Manager vacancy in Sutton. Salary : £46,265 - £54,544 Commencement on the salary range is subject to comparable skills and experience. ...

Are you an experienced clinical trial manager looking for a new opportunity? We are looking for a Senior Trial Manager to join our team. #ResearchJobs

Find out more and apply here: jobs.icr.ac.uk/vacancies/13...

09.01.2026 15:56 👍 0 🔁 2 💬 0 📌 0

🗓️One week today!

🙌Join Prof Emma Hall & Claire Snowdon from the @icr-ctsu.bsky.social to learn how Clinical Trials Units can elevate your research, or your career!

⤵️Register below

06.01.2026 09:14 👍 1 🔁 2 💬 0 📌 0