David Cleary's Avatar

David Cleary

@bacterioskeptic

Assistant Professor in Microbial Genomics (#microbiome, #pneumococci, #haemophilus). My views not UoB. Husband, dad, music miserablist and egg chasing.

347
Followers
331
Following
134
Posts
06.12.2023
Joined
Posts Following

Latest posts by David Cleary @bacterioskeptic

Post image

Midway through the #AMGDMar26 course and grateful to @helenmcneil.bsky.social of @microbesng.bsky.social for coming along and talking to attendees. Also gives them a much needed rest from hearing my voice!!!

11.03.2026 16:27 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Central station main entry facing northbound toward the clock reading 05:10

Central station main entry facing northbound toward the clock reading 05:10

Post image Post image

Early start Monday morning to travel down to Birmingham for #AMGDMar26
Intentions of updating the timeline on the train were derailed by having minimal arm space and musical chairs. Nutrition provided by Greggs.

11.03.2026 11:03 πŸ‘ 8 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0
A blue sky with some clouds above a red brick building to the left and a grey building in the centre with the university of Birmingham crest

A blue sky with some clouds above a red brick building to the left and a grey building in the centre with the university of Birmingham crest

A computer screen showing a terminal inside a browser running fastqc on a number of samples

A computer screen showing a terminal inside a browser running fastqc on a number of samples

Day 2 of #AMGDMar26 🧬 was a lovely sunny day on campus @unibirmingham.bsky.social β˜€οΈ

Which alongside cake and the aim of saving the world (see Day 1) provided ample motivation for learning a whole lot about what to do with Illumina sequencing outputs πŸ’»

11.03.2026 08:30 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Tidy desk set up. On the left; white coursework book and notebook with the course logo on the front. On the right the laptop with desert lock screen.

Tidy desk set up. On the left; white coursework book and notebook with the course logo on the front. On the right the laptop with desert lock screen.

Brown envelope with red top secret stamp beside course notebook

Brown envelope with red top secret stamp beside course notebook

Plenty of merch #AMGDMar26 including a tote bag, j’adore a tote bag. Notebook and laptop sticker all with the course logo on. #yesplease
Also looking forward to completing a top secret task. Applying skills to a fictional scenario. Once more. #yesplease

11.03.2026 11:03 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Flat lay of a tote bag and booklet branded with the Analysing Microbial Genomic Data logo (a laptop showing a DNA double helix and microbes) and a sheet of paper that reads Human Bingo

Flat lay of a tote bag and booklet branded with the Analysing Microbial Genomic Data logo (a laptop showing a DNA double helix and microbes) and a sheet of paper that reads Human Bingo

A folded letter marked as classified with portions blacked out, suggesting the participants of the course must solve a fictional act of bioterrorism

A folded letter marked as classified with portions blacked out, suggesting the participants of the course must solve a fictional act of bioterrorism

Day 1 of #AMGDMar26 🧬 started with an icebreaker that was actually fun 😱!

And I cannot wait to live my science fiction dreams over the next few days 🀩

Oh and a tote bag?! Great start to the week!

09.03.2026 19:18 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Mags is a white woman and has short curly ginger hair and is wearing a yellow raincoat, she is smiling at the camera and pointing upwards with her left hand. She is pointing at a brick building behind her with a railways sign, university, and the university of Birmingham crest

Mags is a white woman and has short curly ginger hair and is wearing a yellow raincoat, she is smiling at the camera and pointing upwards with her left hand. She is pointing at a brick building behind her with a railways sign, university, and the university of Birmingham crest

Made it to Birmingham @unibirmingham.bsky.social for a week of microbial genomics fun! πŸ§«πŸ§¬πŸ’» #AMGDMar26

09.03.2026 16:19 πŸ‘ 11 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Post image

Today is the start of the 5th Analysing Microbial Genomic Data course at @unibirmingham.bsky.social #AMGDMar26 - in the last three years we’ve trained nearly 80 attendees from six countries and multiple UK universities

09.03.2026 09:54 πŸ‘ 22 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

β€œIf you hear a voice within you say β€˜you cannot paint,’ then by all means paint, and that voice will be silenced.”

Vincent Van Gogh

07.03.2026 08:31 πŸ‘ 37 πŸ” 10 πŸ’¬ 2 πŸ“Œ 0
Fig. 3. (a) Pinpoint MNWGS58T colonies on blood agar after 24 h of incubation (37 Β°C, 5% CO2). (b) Mature MNWGS58T colony on blood agar after 48 h of incubation (37 Β°C, 5% CO2). (c) Gram stain of MNWGS58T showing Gram-positive rod-shaped cells with coryneform morphology.

Fig. 3. (a) Pinpoint MNWGS58T colonies on blood agar after 24 h of incubation (37 Β°C, 5% CO2). (b) Mature MNWGS58T colony on blood agar after 48 h of incubation (37 Β°C, 5% CO2). (c) Gram stain of MNWGS58T showing Gram-positive rod-shaped cells with coryneform morphology.

Corynebacterium drakensteinense sp. nov., isolated from the nasopharynx of a healthy South African infant. Published Open Access and fee-free in IJSEM using a Publish and Read agreement: https://doi.org/10.1099/ijsem.0.007068
#IJSEM

07.03.2026 11:00 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Great news for the toxic PI that wants RNA seq data analysed in under a minute.

07.03.2026 02:21 πŸ‘ 13 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0

The School of Biosciences at University of Birmingham is recruiting FIVE Assistant/Associate Profs in areas including fungal biology, plant science and bioengineering. Full details below πŸ„πŸŒΎπŸ§¬πŸ§«

04.03.2026 15:17 πŸ‘ 10 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0

Got silly at end but that was one of the finest Scotland performances I can recall.

07.03.2026 15:58 πŸ‘ 5 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0

Anyone else think this would be a 90 point game and a victory to Scotland? Get in!

07.03.2026 15:58 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

This lot almost lost to Wales last week.

07.03.2026 15:31 πŸ‘ 111 πŸ” 8 πŸ’¬ 15 πŸ“Œ 1

Dupont is just the best all-rounder in the game's history.

07.03.2026 14:31 πŸ‘ 45 πŸ” 2 πŸ’¬ 5 πŸ“Œ 1

Could we actually do this?? #SCOvFRA #GuinnessM6N or is this whiskey I’m drinking getting the better of me?

07.03.2026 14:47 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
Preview
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses - Nature Immunology Patin and colleagues present a mineable Resource database for identifying demographic and genetic factors that impact antiviral antibody repertoires in humans.

🀯
*PhiPseq of 108 health/envt variables + human genetic variation maps antibody repertoire in 1,212 adults.
*Age, sex, birth continent affect specific viral epitopes
*Abs vs variable flu epitopes decrease w/age
*Viral Abs & host genetics affect autoimmune disease risk www.nature.com/articles/s41...

17.02.2026 01:32 πŸ‘ 8 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
Preview
An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim - Genome Biology Background The human pathogen Haemophilus influenzae was the main cause of bacterial meningitis in children and a major cause of worldwide infant mortality before the introduction of a vaccine in the ...

Forgotten how cool this paper was. In particular what it (potentially) says about the emergence of capsulated H. influenzae link.springer.com/article/10.1...

16.02.2026 18:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Dynamics of a large multidrug-resistant plasmid encoding New Delhi metallo-Ξ²-lactamase-1 and oxacillinase-58 carbapenemases in Acinetobacter baumannii clinical isolates from a tertiary hospital in Mal... Acinetobacter baumannii carrying the bla NDM-1 gene, which encodes New Delhi metallo-Ξ²-lactamase-1 (NDM-1), exhibits resistance to nearly all Ξ²-lactams and is not affected by Ξ²-lactamase inhibitors, l...

New paper out with colleagues from Malaysia www.microbiologyresearch.org/content/jour... #microsky

16.02.2026 14:19 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
a man in a suit and tie stands behind a podium and says " that hurt my feelings " ALT: a man in a suit and tie stands behind a podium and says " that hurt my feelings "
14.02.2026 19:05 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

From my days as a youngster I can absolutely tell you that is only a very recent development

14.02.2026 18:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Better luck next year πŸ˜‰

14.02.2026 18:47 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Gregor Townsend job security for life

14.02.2026 18:32 πŸ‘ 85 πŸ” 6 πŸ’¬ 19 πŸ“Œ 1

I don’t want Pollock to be the one to turn this around

14.02.2026 17:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It’s more the massive early lead

14.02.2026 17:03 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Well this is unfamiliar territory #SCOvENG #GuinnessM6N

14.02.2026 16:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

GREGOR TOWNSEND CONTRACT EXTENSION

14.02.2026 16:57 πŸ‘ 54 πŸ” 4 πŸ’¬ 3 πŸ“Œ 1
14.02.2026 06:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

Incredible time at #AIR2026 covering breadth of respiratory infection, microbiomes and immunology with some really beautiful biology. Thanks to fellow committee members @resp-micro.bsky.social @drclairesmith.bsky.social @ewanharrison.bsky.social , Alex Kayongo and organisers @eventswcs.bsky.social

13.02.2026 18:39 πŸ‘ 15 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
Post image

Fantastic final day at #AIR2026. A masterclass in in vitro modelling by Scott Randall followed by a great panel discussion with funders @asthmaandlung.org.uk @wellcometrust.bsky.social @cysticfibrosis.org.uk @karlstaples.bsky.social

13.02.2026 16:53 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0