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Reichow Lab

@reichowlab

Steve Reichow (PI), Laboratory of Biomolecular #CryoEM at Oregon Health & Science University (OHSU) and Pacific Northwest Cryo-EM Center (PNCC) β„πŸ”¬ https://www.reichowlab.com/

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02.10.2023
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Latest posts by Reichow Lab @reichowlab

Stunning illustrations and animations!

08.03.2026 16:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Senior Scientist, Protein Sciences in South San Francisco, California, United States of America | Research & Development at Genentech Apply for Senior Scientist, Protein Sciences job with Genentech in South San Francisco, California, United States of America. Research & Development at Genentech

Our department at Genentech is hiring. We're looking for a freshly-minted PhD (0-3 years) protein biochemist / structural biologist to join as a Sr Scientist. A rare opportunity to join our group leader job family at a more junior level than we usually hire.

24.02.2026 16:55 πŸ‘ 55 πŸ” 57 πŸ’¬ 2 πŸ“Œ 0
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πŸ§ͺHelp needed!

I am currently gathering ideas for a new and updated Blender course tailored for chemists. Besides importing molecules into Blender, what topics or features would interest you the most?

Any input is highly appreciated 😊

19.02.2026 10:48 πŸ‘ 8 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0
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The next #CryoEM Current Practices Webinar speaker is Vladimir Kolyadko from Children’s Hospital of Philadelphia speaking on "Cryo-EM of Liposome-Assembled Macromolecular Complexes to Reveal Protein-Membrane Interactions in Hemostasis" 2/26/2026 at 12PM ET / 9AM PT

us02web.zoom.us/webinar/regi...

20.02.2026 02:12 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Euler Hunt Can you find the Euler angles of a cryo-EM projection?

I had Claude make this as a mini-game for Relay's disconnect screen (like Chrome's dinosaur), but then pivoted to stand-alone. In this game, you have to find Euler angles matching the target projection, i.e. cosplay RELION. It can be pretty hard. Works on mobile too! warpem.github.io/euler-hunt/

16.02.2026 03:13 πŸ‘ 46 πŸ” 15 πŸ’¬ 0 πŸ“Œ 3
Cryo-electron tomogram on a navy background with text: Cryo-ET Data Processing Workshop. June 7-11, 2026

Cryo-electron tomogram on a navy background with text: Cryo-ET Data Processing Workshop. June 7-11, 2026

Join us this summer for U-M's 2026 #CryoET Data Processing Workshop!
This four-day workshop will introduce participants to standard image processing packages and all aspects of cryo-ET data processing.
Apply by March 20: myumi.ch/lsi-cryo-workshop-2026

@jbquerido.bsky.social @shyamalm.bsky.social

09.02.2026 17:54 πŸ‘ 8 πŸ” 6 πŸ’¬ 0 πŸ“Œ 2
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Looking forward to #BPS2026 in San Francisco?

Come by the NIH sponsored Transformative High-Resolution Cryo-Electron Microscopy National Centers for #CryoEM at booth 410.

Our mission is to broaden access to high-resolution cryo-electron microscopy and tomography technologies - cryoemcenters.org

05.02.2026 23:36 πŸ‘ 16 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
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GitHub - GrotjahnLab/surface_morphometrics: Morphometrics for Membrane Surfaces Segmented from Cryo-ET or other volumetric imaging. Morphometrics for Membrane Surfaces Segmented from Cryo-ET or other volumetric imaging. - GrotjahnLab/surface_morphometrics

I've been working on Surface Morphometrics for a new version (coming soon), and made some significant (AI-assisted) performance improvements, especially in pycurv (20-50x!). If you've had technical issues or just felt like it was too slow, give it another try! #teamtomo github.com/GrotjahnLab/...

04.02.2026 00:32 πŸ‘ 36 πŸ” 15 πŸ’¬ 1 πŸ“Œ 0

Are you a cell biologist who secretly thinks cellular cryo-electron tomography is just George Palade-era EM, but fancier?

Join this webinar to see how modern #teamtomo has shifted from pretty pictures to quantitative, local membrane biology, and how that changes the questions we can ask.

01.02.2026 18:54 πŸ‘ 26 πŸ” 9 πŸ’¬ 1 πŸ“Œ 1
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Stories from the scientist who changed how we visualize proteins - Nature Reviews Chemistry Ahead of her 85th birthday, Jane Richardson, Professor of Biochemistry at Duke University, discussed her life in science from making her own telescope to developing the ribbon diagrams for the 3D stru...

this was published this week, in case you haven’t seen it: www.nature.com/articles/s41...

28.01.2026 22:08 πŸ‘ 14 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
Statement from Michael and Susan Pretti
Parents of Alex Jeffrey Pretti

β€œWe are heartbroken but also very angry.

Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact.

I do not throw around the β€˜hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed. 

Please get the truth out about our son. He was a good man. Thank you.

Statement from Michael and Susan Pretti Parents of Alex Jeffrey Pretti β€œWe are heartbroken but also very angry. Alex was a kindhearted soul who cared deeply for his family and friends and also the American veterans whom he cared for as an ICU nurse at the Minneapolis VA hospital. Alex wanted to make a difference in this world. Unfortunately, he will not be with us to see his impact. I do not throw around the β€˜hero’ term lightly. However, his last thought and act was to protect a woman. The sickening lies told about our son by the administration are reprehensible and disgusting. Alex is clearly not holding a gun when attacked by Trump’s murdering and cowardly ICE thugs. He had his phone in his right hand and his empty left hand is raised above his head while trying to protect the woman ICE just pushed down, all while being pepper sprayed. Please get the truth out about our son. He was a good man. Thank you.

Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti.

"Please get the truth out about our son."

25.01.2026 00:43 πŸ‘ 24925 πŸ” 12850 πŸ’¬ 200 πŸ“Œ 448
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in case you're curious about how angry Minnesota is about ICE, it was -20 today

24.01.2026 00:38 πŸ‘ 50064 πŸ” 14414 πŸ’¬ 968 πŸ“Œ 852
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Visualizing Structure, Dynamics and Interactions Using Cryo-EM Visualizing Structure, Dynamics and Interactions Using Cryo-EM on Simons Foundation

Join us for a Presidential Lecture on 1/28 with Eva Nogales: "Visualizing Structure, Dynamics and Interactions Using Cryo-EM." Register: https://www.simonsfoundation.org/event/visualizing-structure-dynamics-and-interactions-using-cryo-em/ #science #biology

21.01.2026 16:04 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

We are running the cryo-ET image processing workshop again this year! Come learn everything tomo: STA, segmentation, heterogeneity analysis from @baradlab.com @williamnwan.bsky.social and others!

Apply!

20.01.2026 14:20 πŸ‘ 22 πŸ” 18 πŸ’¬ 0 πŸ“Œ 1
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Bridging Cellular and Structural Biology Through Cryo-electron Tomography - ASCB Cellular cryo-electron tomography (cryo-ET) holds the grand promise of integrating cellular architecture with molecular structure. Yet, for many cell biologists, this method can seem technically…

Curious about cryo-electron tomography but not sure how it fits into your research? This ASCB webinar with Danielle Grotjahn, Ph.D., breaks down what cryo-ET can do, where it shines, and how it works alongside other imaging methods.

16.01.2026 22:19 πŸ‘ 19 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1
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2026 Summer Intern - Agents for Structural Biology in South San Francisco, California, United States of America | Students & Graduates at Genentech Apply for 2026 Summer Intern - Agents for Structural Biology job with Genentech in South San Francisco, California, United States of America. Students & Graduates at Genentech

Internship opportunity! @jackn.bsky.social and I have opened two Summer Intern positions at Genentech to build structural biology agents. If you are a (pre-PhD) #cryoEM or #Xray structural biologist with strong computational skills & motivation, please apply!

05.01.2026 20:56 πŸ‘ 14 πŸ” 15 πŸ’¬ 1 πŸ“Œ 1
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Cryo-Electron Microscopy Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Interested in learning or strengthening skills in #CryoEM single particle analysis? Apply for the CSHL cryo-EM course happening in March! This is a super intense 2 week course covering theory up through data deposition. Apps due Jan 9! Info here: meetings.cshl.edu/courses.aspx...

30.12.2025 16:16 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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NIH Agrees to Evaluate and Complete Review on Stalled Scientific Grant Applications | American Civil Liberties Union Parties resolve claims on behalf of applicants harmed by unlawful directives

Yet again it pays to speak up & fight back!

NIH has agreed to β€œevaluate each application individually and in good faith” for plaintiffs whose applications were unlawfully held in fiscal year 2025. In return, the plaintiffs dropped the lawsuit. www.aclu.org/press-releas...

30.12.2025 03:45 πŸ‘ 66 πŸ” 29 πŸ’¬ 1 πŸ“Œ 2

JCB’s Cover of the Year voting is open!
I’ll just say… they are all gorgeous, but April has my heart πŸ˜β„οΈπŸ”¬

#teamtomo @attychang.bsky.social

22.12.2025 20:03 πŸ‘ 18 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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My lab in the NIH Intramural Program (Bethesda, MD) will be recruiting postdoctoral fellows over the next year with flexible start dates. We work on nanoscale cellular imaging of the plasma membrane and related organelles. Please reach out if you’re interested. www.training.nih.gov/jobs/pdp-053...

22.12.2025 14:57 πŸ‘ 59 πŸ” 44 πŸ’¬ 1 πŸ“Œ 3
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As 2026 chair of the Biophysical Society Cryo-EM subgroup, I am thrilled to announce that Dr. Melanie Ohi has been selected as the recipient of the June Almeida Award: an honor recognizing women scientists whose leadership, scholarship, and mentorship have profoundly shaped the field of cryo-EM.

11.12.2025 14:06 πŸ‘ 8 πŸ” 3 πŸ’¬ 2 πŸ“Œ 1
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Method of the Year 2025: electron microscopy-based connectomics - Nature Methods A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...

www.nature.com/articles/s41...

08.12.2025 23:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I'm giving a talk at One World Cryo EM (cryoem.world) tomorrow at 11:00am EST. Topic is 'Deconstructing Algorithms for β€œDiscrete” Heterogeneity in Cryo-EM'. Sign up for their mailing list to tune in!

02.12.2025 19:55 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Out today, we can now multiplex receptor mapping at synapses thanks to a dimeric gold nanoparticle label optimized by Hoyoung that's distinguishable from monomers!

Dimeric gold nanoparticles enable multiplexed labeling in cryoelectron tomography | PNAS www.pnas.org/doi/10.1073/...

24.11.2025 20:54 πŸ‘ 16 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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🌟 WeINSPIREBio is hosting its first event!

On Dec 4, we’re running a webinar:

Structures of Success: Career Journeys of Women in Structural Biology

If you work in SB, drug discovery, or just like hearing career stories from brilliant people, join us! And please share πŸ™πŸΌ

lnkd.in/ewjD5WPt

#cryoEM

24.11.2025 15:17 πŸ‘ 11 πŸ” 14 πŸ’¬ 1 πŸ“Œ 0
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a brown puppy is being held by a person with the words " really " on the bottom ALT: a brown puppy is being held by a person with the words " really " on the bottom

So, if an institute or center decided not to fund any grant from University X or on Topic Y, then there would be no documentation in the official grant files about these applications.

2/2

24.11.2025 00:29 πŸ‘ 65 πŸ” 12 πŸ’¬ 2 πŸ“Œ 0

Prohibitins aren’t hanging out just anywhere in the membrane β€” they prefer the πŸ’β€β™€οΈπŸ’Žβœ¨VIP sectionπŸ’…πŸͺ©πŸ₯‚

Lab all-star @mmedina300kv.bsky.social maps these microdomains using cryo-ET + surface morphometrics.

s/o to #teamtomo #cryoET co-authors
@hamid13r.bsky.social
@attychang.bsky.social
@baradlab.com

17.11.2025 00:22 πŸ‘ 57 πŸ” 18 πŸ’¬ 0 πŸ“Œ 2

Calcium and magnesium in the pore of NMDA receptors!

Lipids play an unexpected role. The hydration shells of Ca2+ and Mg2+ could be the difference between permeation and block. So much physiology in the energetics of H2O.

Very stimulating work! Congrats @lab-furukawa.bsky.social

#iglurs

08.11.2025 06:30 πŸ‘ 8 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Science, from Portland

31.10.2025 16:44 πŸ‘ 100 πŸ” 16 πŸ’¬ 3 πŸ“Œ 0
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Chris Russo and Anastasiia Gusach have developed a new method to prepare #cryoEM samples that avoids protein damage during freezing

Read more: www2.mrc-lmb.cam.ac.uk/a-new-method...

#LMBResearch

22.10.2025 16:41 πŸ‘ 61 πŸ” 30 πŸ’¬ 0 πŸ“Œ 2