Shane Herbert

Cell state-specific cytoplasmic density controls spindle architecture and scaling - Nature Cell Biology Kletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a det...

🍹Kletter et al. show that cell state-specific cytoplasmic density controls spindle architecture and scaling in neural differentiation, suggesting that the physical properties of the cytoplasm are a determinant in #organelle size control.
bit.ly/4mhMvsU

mRNA trafficking directs cell-size-scaling of mitochondria distribution and function - Nature Communications How mitochondria positioning dynamically adapts to changes in cell shape is poorly understood. Here, Bradbury et al. show that cell-size-dependent trafficking of TRAK2 mRNA underpins the cell-size-sca...

If you’ve ever wondered how cells tune positioning of organelles in response to cell shape change, and what happens when this goes wrong, please check out our new manuscript – mRNA trafficking controls cell-size-scaled organelle dynamics! www.nature.com/articles/s41...

Looking foward to the Northern(ish) Developmental Biology Meeting 2025 next week @sheffielduni.bsky.social! Thanks to the organisers @shaneherbert.bsky.social Raman Das @tsakiridis.bsky.social @kyracampbelllab.bsky.social

Frictiotaxis - amazing!

Cool - ever multitalented endothelial cells!

It's great to have media attention on our recent paper, but, some of these 'news' articles are completely wacky! 🤣

I really hope I can make this - and seems crazy that this is the 1st UK meeting! Should be excellent!

Who needs Pubmed when you have your mum! 🤣

Our cells can divide in a completely unexpected way A different kind of human cell division could improve our understanding of cancer and help us grow specific tissues

Bit of a nerdy dream for our paper to be covered by @newscientist.com! And lovely kind words from @buzzbaum.bsky.social. Just a shame that the daughter cells on the cover image are round and symmetric 🤣. www.newscientist.com/article/2478... www.newscientist.com/article/2478...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...