No need to wait until September: We’ve identified the causes of autism and even some of the environmental chemicals interacting with autism genes involved early fetal neurodevelopment during pregnancy
New Acute Migraine Management Guidelines:
- Triptans combined with NSAIDs (e.g., sumatriptan + naproxen) offer the highest net benefit
- Triptan + acetaminophen is also beneficial.
- Monotherapies are effective, but less so than combination therapy.
www.acpjournals.org/doi/10.7326/...
Great review from JAMA on Iron deficiency in Adults. Great topic with very little CHE on the topic. jamanetwork.com/journals/jam...
#CardiacRehab #ESCPrev2025 #CVprev
Smoking Cessation key component but how do we do it correctly?
Study used Motivational Intervention had better cessation rates 🆚 control group
✨ NNT=4
✨ ⬇️ ASCVD events
Such an important study of what we can do in CR!
@escardio.bsky.social
Evidence based on the literature for various traits and disorders
How do GLP-1 drugs affect cognitive and mental health disorders? A comprehensive review www.nature.com/articles/s44...
New Liver disease review on MetALD. Nice review if you are interested in metabolic and alcohol-related liver disease
MetALD: Clinical aspects, pathophysiology and treatment - JHEP Reports www.jhep-reports.eu/article/S258...
Assessment and management of frailty in individuals living with dementia: expert recommendations for clinical practice - The Lancet Healthy Longevity www.thelancet.com/journals/lan... #frailty #dementia
Psoriatic Arthritis and comorbidity management - Quick review of expert care of patients with PsA.
academic.oup.com/rheumatology...
New Rheumatology guideline on Sjogren Disease - Wicked condition for affected patients, for my specialty colleagues, worth a quick read.
academic.oup.com/rheumatology...
MASLD pharmacotherapy review - If you are interested in learning more about the new treatments for MASLD, MASH and fibrosis, there is a great review at:
www.nature.com/articles/s41...
#MASLD, #NAFLD, #MASH
Redefining obesity. It is time.
📏BMI is NOT a direct measure of fat
📏BMI does NOT establish the distribution of fat
📏BMI cannot determine with excess fat is a health problem
@thelancet.bsky.social
Lancet Commission
📎 www.thelancet.com/commissions/...
New diabetes in pregnancy study of oral antihyperglycemic agents vs. insulin. Insulin is still king when looking at large for gestational age measurement.
jamanetwork.com/journals/jam...
Physical activity and weight loss - Common question at this time of year. Moderate weight loss for aerobic exercise. Key findings:
- Each 30-minute increase in weekly aerobic exercise leads to measurable reductions in weight, waist circumference, and body fat.
jamanetwork.com/journals/jam...
COPD Non-Pharm Recommendations - Nice review of infection prevention, nutrition, physical activity and smoking cessation. Commonly missed with these patients. hashtag#COPD
journals.lww.com/ijom/fulltex...
New Alzheimer's Disease Guideline - 19 recommendations for clinicians. Includes recommendations for primary care clinicians as well. #Alzheimer's #guideline
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Figure. Antibody Responses Among Immunocompromised Adults Following Respiratory Syncytial Virus (RSV) Vaccination
While immunocompromised individuals had a heterogeneous antibody response to RSV vaccines, those who received the adjuvanted RSVPreF3-AS01 vaccine showed better neutralization.
ja.ma/4iVzJzy
E-cigarettes are likely safer than combustible tobacco, but not safe. Increasing evidence of harm. This article reviews the CVD risk with e-cigarettes. #smokingCessation #tobacco
www.wjgnet.com/1949-8462/fu...
E-cigarettes and oral health - Although safer than combustible tobacco, there are risks with e-cigarette use. Increased periodontal disease, dental caries, oral mucosal lesions and teeth staining. #e-cigarettes
doi.org/10.3390/dj12...
Managing GLP-1 RA GI-related adverse effects - Common question, new review. Some new tips for your patients. #diabetes, #obesity, #GLP-1RA
www.dovepress.com/dietary-reco...
Pediatric influenza vaccine effectiveness Study - We know that 6 months to 5 years is a high-risk group of influenza-related complications. The vaccine reduced the risk of ED visits, noncritical and critical influenza by about 50%. Really supports use in this group.
jamanetwork.com/journals/jam...
New Long COVID Data - MMWR published today that 1 in 5 Adults experiencing long COVID had major limitations on their ability to perform daily functions. In this survey 6.4% of US adults were reporting they had long COVID when surveyed.
www.cdc.gov/mmwr/volumes...
Dysplipidemia manage - "Lower is better for longer and the earlier the better"
rdcu.be/d33UT
The Role of Primary Care in Achieving Life’s Essential 8: A Scientific Statement From the American Heart Association
www.ahajournals.org/doi/10.1161/...
Just a reminder that iron deficiency is incredibly common
jamanetwork.com/journals/jam...
And reference intervals are garbage.
Join us at 2pm today #ASH24 in SDCC room 11 #ChoosingFairly to learn how you can work to change that!
Genital herpes is a common sexually transmitted infection caused by herpes simplex virus (HSV).
This JAMA Patient Page describes genital herpes and its symptoms, diagnosis, treatment, and prevention measures.
ja.ma/498JfLi
Mpox is a self-limited viral infection primarily spread through skin contact, but poses significant risks for the immunocompromised.
by Titanji BK, Hazra A and Zucker J in JAMA #MedSky
📖 read the article:
Smoking decreases vaccine immune response - As if we need another reason to quit, smokers have a 48% higher risk of diminished immune response to vaccines (especially COVID-19 and Hep B)
www.mdpi.com/2076-393X/12...
New review of Iron Status during pregnancy: They recommend screening during pregnancy www.sciencedirect.com/science/arti...
Alcohol use when using antiobesity medications - almost 50% of participants reduced alcohol.
jamanetwork.com/journals/jam...
New International Scabies Guidelines - Topic that is rarely discussed. Detailed review.
onlinelibrary.wiley.com/doi/10.1111/...
