@clairewyart
Team Leader @Paris Brain Institute & Inserm Director. Fascinated by navigation, movement and brain body interactions. Passion for interdisciplinary training. Knows biodiversity and climate demand changing my game... more on wyartlab.org
Motor Folks: a nice opportunity to present your work & get feedback! BTW registration to the Conference "Searching Principles in Motor Control" on Sept 23-24, 25 is free but mandatory, please sign up and present your work to the French community ! motorconference.sciencesconf.org?lang=en
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
We work on humans with @antoniocbscosta.bsky.social @marcoromanato.bsky.social @wyartlab.bsky.social predicting effects of #DBS in Parkinson's Disease patients. Yet, understanding cellular & circuit mechanisms underlying behaviour require model organisms 🎏🐭🪱🪰 & cannot be done in humans nor organoids
Congratulations to the 2025 George Streisinger Award Winners! And, thank you, to your contributions to the #zebrafish field! #IZFC2025
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social @jasperjanssens.bsky.social and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
Chronic back pain affects most of us eventually, and ageing discs are often to blame. But cellular senescence may not be irreversible.
This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
Ferenc is great, super opportunity!
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
Dear all, PLEASE add comments on the importance of model organism research at this link:
NIH suspending or terminating grants with a very broad definition of dangerous gain of function research (which appears to include standard safe laboratory procedures)
www.science.org/content/arti...
Figure 1: Acoustic differences in isolation bleats (left side of panel) and in pre-feeding bleats (right side of panel) according to the ‘line’ (S+, S- and intermediate not selected when considering the isolation calls). A: Spectrogram of calls of one representative S+ female and one representative S- female according to the context of recording (FFT wl = 2048 pts, ov=90%, frequency sampling=44.1 kHz, amplitude range from blue to red color scale: -70 to 0dB). B: Averaged mean-spectrum (and standard deviation in shade) over the total amount of calls analyzed per line and contexts (Number of isolation calls: N=322 from S+, N=67 from S-, N=899 from not selected females; Number of pre-feeding calls: N=262 from S+, N=257 from S- females). C: Acoustic parameters explaining the Acoustic Score computed using a LDA on ‘line’ within each context of recording (isoLD for isolation and pre-feedLD for pre-feeding). For isolation calls, the predictions of isoLD for calls recorded in non-selected females and comparisons (groups with different letters illustrate statistical differences, see supplementary statistical tables S3 for model estimates and pairwise comparisons).
V cool work from @ebriefer.bsky.social et al on how selection for sociability alters vocal signals (in sheep!) bit.ly/40AHKTd
1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability
2. More selection for sociability ➡️ Less vocal individuality
#prattle 💬 #bioacoustics
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
It took us many years to improve idtracker.ai in both accuracy and tracking time. Here it is.
Downstream @etlunsford.bsky.social mapped how the corresponding interneurons in the brainstem project onto reticulospinal neurons to select the steering command eliciting either forward or turns ... recalling the pioneering work of @daniobrain.bsky.social on optical motor response to flow! (5)
The tackle this question, @etlunsford.bsky.social 🌬️ stimulated each & all neuromasts along the body & discovered a simple principle within the brainstem !! Namely, information on location & direction is encoded in an egocentric referential around the center of mass! www.biorxiv.org/content/10.1...
Fish display mechanosensors called neuromasts covering their body from head to tail. In each neuromast, hair cells can sense changes in water flow along different directions in the anteroposterior axis, either tailward or headward. How does the brain compute the flow information across the body? (2)
By combining controlled mechanical stimulation & whole brain #imaging, @etlunsford.bsky.social revealed an essential principle 💡... Mechanosensory inputs from any directions along the body are encoded relative to the center of mass (COM)! Recalling #olfaction with odors encoded by pleasantness (4)
Let's share @etlunsford.bsky.social's work : to survive, animals avoid drifting involuntarily in their environment. While humans rely on visual & vestibular cues, birds & fish need to sense complex flow changes of the external fluid (air/water) around them to select motor actions. How do they do?(1)
hi BlueSky, introducing @wyartlab.bsky.social @zebrafishrock.bsky.social "cuvée" 🍷 biodynamic organic & bubbly 2025!! Located in @institutducerveau.bsky.social 🎏 migrating in summer @sorbonne-universite.fr to observatory or in @standrewspsyneuro.bsky.social to learn #MotorControl, #morphogenesis!
⚡Awesome days of scientific discussions around the topic of resilient motor circuits in Parkinson's disease & underlying genetic conditions featuring Prof. Alexis Brice, Leonard Constien, Ananelle Redon, Ninon Peysson @kevinfidelin.bsky.social among others⚡
🚨Job opportunity 🚨
The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
Great seminar this morning scheduled this morning from Andre Brown @imperialcollegeldn.bsky.social @institutducerveau.bsky.social dont miss it !
Congrats Laura, your science (and neuronal morphologies) is (are) beautiful ✨🌳
Motor afficionados: Don't miss great talks coming up this week #CAJAL #Training @univbordeaux.bsky.social #MotorControl featuring in particular @olekiehn.bsky.social #FENS president & Brain Prize 2022 showing his contribution to understanding *Circuits for Movements* on Thursday Dec 5th at 11 AM ✨
The Nordic #neuroscience societies welcome you all to the FENS Regional Meeting in Oslo next year - the first time ever in a Nordic country!
The CALL FOR SYMPOSIA is still open until 30 November. Submit now!
frm2025oslo.no
#FRM2025 #brain #FENS
@pirtahotulainen.bsky.social @olekiehn.bsky.social
Congrats @adrienjouary.bsky.social @daniobrain.bsky.social !! beautiful use of AI to automate the categorisation of single locomotor bouts of #zebrafish, following the pioneering work of João Marques. Well done!
So MUCH fun organizing the Cajal Brain Prize Motor School in the honour of Silvia Arber, Martyn Goulding and Ole Kiehn for 20 early career students and postdocs wanting to learn by making their hands dirty when comparing 🐸🎏 🐭🐒 🚶♂️locusts, frogs, fish, mice, macaques, humans and more!
📣 Time to register to the 7th European Zebra 🐟 Principle Investigator Meeting to be held in Paris Brain Institute, April 2- 5, 2025. Early 🦜 until Dec 15th, 2024. Abstract submission is now open. Apply! Share latest results & fun ! 👉 lnkd.in/e4pDe7uh #zebrafish www.europeanzebrafishpimeeting.com
