Zandrea Ambrose, Ph.D. 🦠🧬πŸ§ͺ🧫's Avatar

Zandrea Ambrose, Ph.D. 🦠🧬πŸ§ͺ🧫

@zandrea

Virologist & Professor, Pitt Dept. of Microbiology & Molecular Genetics and former Director of @Pitt-PMI.bsky.social Seattle native living in Pittsburgh. Website: http://ambrose-lab.com

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Latest posts by Zandrea Ambrose, Ph.D. 🦠🧬πŸ§ͺ🧫 @zandrea

Just walked by a colleague's classroom after my class finished and he was talking about Elvis, getting blank stares and so he had to ask "Does anyone know who Elvis Presley is?"

It's rough out here on these teaching streets.

09.03.2026 20:25 πŸ‘ 5150 πŸ” 342 πŸ’¬ 270 πŸ“Œ 207

PMI Professor and @asm.org President-Elect @vscooper.micropopbio.org met with congressional staff last week to advocate for science and public health. πŸ‘πŸΌ

09.03.2026 17:00 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Genetically engineered eye-colonizing microbes that deliver the anti-inflammatory cytokine interleukin-10 enhance corneal tissue repair Barrier surfaces harbor tissue-colonizing microbes that can shape local physiology and immunity. During corneal injury, inflammation can delay healing…

Congratulations to PMI’s own Dr. Anthony St. Leger on his recent work published in Cell Reports!

09.03.2026 12:28 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Detailed thread on what this means. And it’s rather terrifying.

09.03.2026 16:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Are gender gaps due to evaluations of the applicant or the science? A natural experiment at a national funding agency Gender gaps in grant funding are attributable to less favourable assessments of women as principal investigators, not of the quality of their proposed research. We discuss reasons less favourable asse...

β€œThese data support the second of our alternative hypotheses; namely, that gender gaps in funding stem from female principal investigators being evaluated less favourably than male principal investigators, not from differences in evaluations of the quality of their proposals.”

09.03.2026 12:45 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Stand Up For Science Founder and CEO Colette Delawalla speaking at the Washington D.C. Take Back Our Science Rally!

Stand Up For Science Founder and CEO Colette Delawalla speaking at the Washington D.C. Take Back Our Science Rally!

Stand Up For Science Founder & CEO Colette Delawalla states three demands:

1. Remove RFK Jr.

2. Reinstate the American Dream of Science.

3. Science should be driven by scientists not political appointees.

Join the fight!
standupforscience.net/march7

07.03.2026 20:13 πŸ‘ 1635 πŸ” 373 πŸ’¬ 15 πŸ“Œ 7
Dr. Jeremy Berg speaking in front of a crowd at Pittsburgh Stand Up for Science.

Dr. Jeremy Berg speaking in front of a crowd at Pittsburgh Stand Up for Science.

It’s @jeremymberg.bsky.social talking at Pittsburgh Stand Up For Science. #StandUpforScience

07.03.2026 19:01 πŸ‘ 73 πŸ” 11 πŸ’¬ 4 πŸ“Œ 0
Stand Up

Stand Up

For Science

For Science

I SUPPORT SCIENCE

I SUPPORT SCIENCE

#StandUpForScience #Pittsburgh

07.03.2026 20:25 πŸ‘ 55 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

See you next Saturday, Pittsburgh!

02.03.2026 15:57 πŸ‘ 16 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

Which one is the MAGA Senator?

05.03.2026 01:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

πŸ€¦β€β™€οΈ

05.03.2026 01:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

With this war on Iran costing $1B per day, we are now at 4$B, an amount that would fund 3,200 five year NIH biomedical research grants.

04.03.2026 20:20 πŸ‘ 227 πŸ” 91 πŸ’¬ 7 πŸ“Œ 10

Not to mention the condescending lesson in how the U.S. Senate works.

05.03.2026 01:12 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Letter from Sen. Fetterman dated March 6, 2026 telling me that he plans to vote for Elise Stefanik for UN Ambassador.

Letter from Sen. Fetterman dated March 6, 2026 telling me that he plans to vote for Elise Stefanik for UN Ambassador.

I wrote to my senators to urge them not to vote for Casey Means for surgeon general. Fetterman responded today (3/4/26), "I voted to confirm Senator Marco Rubio as Secretary of State and plan to do the same for Representative Elise Stefanik as U.S. Ambassador to the UN...." What? πŸ€¦β€β™€οΈ

05.03.2026 01:06 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

See you next Saturday, Pittsburgh!

02.03.2026 15:57 πŸ‘ 16 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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This week's cover @thelancet.com

26.02.2026 23:48 πŸ‘ 3118 πŸ” 1457 πŸ’¬ 44 πŸ“Œ 80
JCI Insight - Antiretroviral treatment does not prevent extrapulmonary tuberculosis during SIV/Mtb coinfection in macaques

New paper in insight.jci.org by my & Ling Lin’s groups! TB is the most common infectious disease that causes death, causing >1 million deaths globally. HIV is the greatest risk factor for TB, causing worse clinical outcomes for both infections. We studied the effect of SIV infection 1/4

26.02.2026 14:28 πŸ‘ 5 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Does suppression of HIV replication protect against severe Mtb infection?

ASCI member Philana Ling Lin & team report on SIV/ART/TB models, finding antiretroviral treatment reduces pulmonary TB pathology, yet does not prevent extrapulmonary spread of TB: doi.org/10.1172/jci....

26.02.2026 21:02 πŸ‘ 3 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0

Stay tuned for our upcoming study where we show how SIV disrupts granuloma function, even during suppressive ART! 4/4

26.02.2026 14:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The surprising extrapulmonary disease even after aggressive ART despite normalized CD4+ T cell counts & subtle changes in CD8+ T cell function underscore the need to understand the immunologic mechanisms of TB progression and how ART modulates immune responses impaired by HIV. 3/4

26.02.2026 14:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

+/- antiretroviral therapy (ART) on Mtb infection. While very early suppressive ART prevented disease progression in lungs & lymph nodes, it did not inhibit dissemination of Mtb outside of the lung. Similarly, ART did not restore impaired T cell responses caused by SIV. 2/4

26.02.2026 14:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
JCI Insight - Antiretroviral treatment does not prevent extrapulmonary tuberculosis during SIV/Mtb coinfection in macaques

New paper in insight.jci.org by my & Ling Lin’s groups! TB is the most common infectious disease that causes death, causing >1 million deaths globally. HIV is the greatest risk factor for TB, causing worse clinical outcomes for both infections. We studied the effect of SIV infection 1/4

26.02.2026 14:28 πŸ‘ 5 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

Hugs πŸ€— to @peterstaley.bsky.social for giving an inspiring Martin Delaney Presentation at #CROI2026 !

23.02.2026 01:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
RFK Jr and Kid Rock

RFK Jr and Kid Rock

Oh no πŸ€¦πŸ»β€β™€οΈ

22.02.2026 23:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I went through the TSA Pre line this morning at 6:45. TSA workers didn’t know about this. πŸ€¦πŸ»β€β™€οΈ

22.02.2026 12:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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DHS pausing TSA PreCheck, Global Entry programs amid funding lapse The suspension is set to start at 6 a.m. ET Sunday, a DHS spokesperson said.

As of 7am, PIT TSA Pre was still open and the agents didn’t have any information about this.

22.02.2026 12:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
A picture of RFK Jr. and Kid Rock in the sauna. The question: Name this band. The answers: Rage Against the Vaccine, Meth Lab for Cutie, Hillbilly Vanilli, Septic & Garfungal, and 30sec to SARS.

A picture of RFK Jr. and Kid Rock in the sauna. The question: Name this band. The answers: Rage Against the Vaccine, Meth Lab for Cutie, Hillbilly Vanilli, Septic & Garfungal, and 30sec to SARS.

πŸ˜‚

21.02.2026 17:54 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

When I’m writing a grant.

20.02.2026 23:36 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
NOT-OD-26-020: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NOT-OD-26-020. OD

🧡Good news out of #NIH today.
(1) NIH is extending #ESI and #K99/R00 eligibility to accommodate researchers whose eligibility would have ended during the previous shutdown. Take a look at NOT-OD-26-020. If your ESI status would have ended in 2025, you get an automatic extension through 2026/03/31.

30.01.2026 19:34 πŸ‘ 63 πŸ” 61 πŸ’¬ 1 πŸ“Œ 1
16.02.2026 18:05 πŸ‘ 4553 πŸ” 1182 πŸ’¬ 65 πŸ“Œ 16