David Nduru

Self-assembling peptide with dual function of cell penetration and antibacterial as a nano weapon to combat intracellular bacteria A nanopeptide with “rapid reach” and “lethal strike” capabilities is identified as an executioner of intracellular bacteria.

Researchers have constructed self-assembled nanopeptides that penetrate cells and target intracellular bacterial infections, which are increasingly difficult to treat due to antibiotic resistance.

Learn more in #ScienceAdvances: scim.ag/414fw2q

@commsbio.bsky.social

Hippo pathway in cancer cells induces NCAM1+αSMA+ fibroblasts to modulate tumor microenvironment - Communications Biology Single-cell RNA sequencing reveals that the Hippo pathway in cancer cells influences the composition of cancer-associated fibroblasts and modulates the tumor microenvironment, thereby promoting cancer...

Our paper was recently published in @naturecomms.bsky.social depicting how Hippo signaling pathway in breast cancer cells remodels the CAF population in TME. I'm glad to have been part of making this conceptual advancement into the field of Cancer biology.
www.nature.com/articles/s42...

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin Maintaining genome integrity is an essential and challenging process. RAD51 recombinase, the central player of several crucial processes in repairing DNA and protecting genome integrity, forms filamen...

NEW in @science.org, so happy to contribute to our understanding of the molecular machine, Fidgetin-like 1 (FIGNL1), and elucidating the mechanism of why cells cannot survive when it is lost! #ScienceResearch science.org/doi/10.1126/... (1/7)

Insulin resistance reduction, intermittent fasting, and human growth hormone: secondary analysis of a randomized trial - npj Metabolic Health and Disease npj Metabolic Health and Disease - Insulin resistance reduction, intermittent fasting, and human growth hormone: secondary analysis of a randomized trial

Pleased to share our recent paper reporting that reduction of #InsulinResistance by low-dose #IntermittentFasting was greater in people with low baseline #HumanGrowthHormone (HGH) #medsky @natureportfolio.bsky.social www.nature.com/articles/s44...

Where are my like minds around here? Someone to hold my hand?🥴🥲