new Lai lab paper @natsmb.nature.com! Dicer is specifically mutated in cancer, but we don't fully understand its molecular/reg impacts. with @danweihuangfu.bsky.social, we characterized the first knockin Dicer hotspot in hESCs, and found unexpected defects in miRNA biogenesis! 🧬 1/4
rdcu.be/eOc0q
As a member of the editorial board for @stemcellreports.bsky.social, I am excited to share that we are looking for submissions in the field of stem cell research! I invite you to submit your work for consideration. invt.io/1bxbz2ji4db @isscr.org #stemcell #DevBio #hPSCs #regeneration
Maria Jasin, whose fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to inherited gene mutations, has been selected as the 2025 recipient of the Pearl Meister Greengard Prize. Congratulations! #WomenInScience
Now accepting applications for our 2026 Cancer Biology & Cancer Engineering programs. Aspiring scientists & engineers will solve fundamental problems in biology & conduct research & develop technology that will help understand, diagnose, & treat cancer.
bit.ly/3WUiuo1
Congratulations to #MSKPostdoc Denis Torre
on being awarded the Damon Runyon Fellowship! 👏👏👏
Keep up the good work!
@damonrunyon.org @mskeducation.bsky.social
📢 Interested in #AI + #PrecisionMedicine?
The NIH PRIMED-AI program has forecasted several new #funding opportunities — covering AI frameworks, validation centers, academic-industry partnerships & more!
📝 FOAs expected soon — stay tuned & start planning!
🔗 More information: dknet.org/about/dknetn...
Traveling to the @isscr.org meeting in HK soon? Feeling like browsing through important #StemCell work published during the past year on your way there? Take a look at our collection of papers published across @natureportfolio.nature.com during the past 12 months!
www.nature.com/collections/...
btw, there's a curious tandem duplication event found in certain primates including humans but not in mice at the NANOG locus. #stemcells #hPSCs
Jielin Yan (recently graduated 🎉🎉) led the discovery of two enhancers regulating NANOG expression in #hESCs via a #CRISPRi screen. It's part of our larger effort characterizing the functions of enhancers and noncoding variant in development and disease @igvfconsortium.bsky.social
Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells: Stem Cell Reports www.cell.com/stem-cell-re...
Lab hiking at Mount Beacon. Great views of the Hudson, a few detours off-trail (in true scientific spirit), and just the right amount of rain. many thanks to Denis Torre for organizing. A beautiful sendoff for lab members (Jielin Yan and Sharon Adeniyi) soon setting off on their own paths.
🎓 Congratulations to the 14 scientists who graduated from the Gerstner Sloan Kettering Graduate School of Biomedical Sciences (GSK) this year!
Learn more about this year's GSK graduates and their accomplishments: bit.ly/3SGB1T8
Hosted Ben Stanger for a seminar and in addition to a great presentation (I'm expecting that!), I also received a surprise!
Thanks @benstanger01.bsky.social
Congratulations to our 2025 graduates! So inspired @carolynbertozzi.bskyverified.social commencement speech. @mskeducation.bsky.social
Congratulations to Dr. Jielin Yan and Dr. Samual Kaplan. So very proud of your accomplishments!
Our "Atlas of Variant Effects 2030 Roadmap" is live: zenodo.org/records/1542...
1/n
One of these studies from @mskcancercenter.bsky.social and the result of the long term commitment to basic stem cell investigation by Lorenz Studer and Viviane Tabar at MSK. Very exciting!
Calling all students in NIDDK relevant disease research fields! 🔬📊 Ready to explore data management, #FAIR data, rigor and reproducibility, and #datascience? The dkNET Summer of Data program offers training to boost your research skills.
Apply now! ✨ dknet.org/about/Summer...
exciting news for our scientific community! www.nygenome.org/news-events/...
Can you explain your doctoral research through interpretive dance?
The deadline for submissions to the 17th annual #DanceYourPhD competition is this week. Submit by 28 March for a chance to win $2000: scim.ag/4gKMnz9
if a non-monotonic response is intriguing to you, stay tuned for another preprint from Jielin on gene dosage responses ...
Congratulations to Dr. Jielin Yan #GSK for successfully defending her PhD dissertation! And a refreshing perspective on a non-monotonic relationship between academic freedom and scientific growth. Check out her preprint here on the discovery of NANOG enhancers www.biorxiv.org/content/10.1....
Tom Maniatis coming in hot in @CellCellPress
to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science.
And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯
www.cell.com/cell/fulltex...
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
#ISSCR joined hundreds of biomedical research organizations to urge House and Senate appropriators to support robust funding for NIH & avoid drastic measures that will slow scientific progress and weaken the U.S. research ecosystem. www.isscr.org/isscr-news/t...
I created a brief spreadsheet of reductions I've heard of so far. Any additions you know of (especially if you have the links/receipts) would be great: docs.google.com/spreadsheets...
I am extremely proud to see our work about Hepatitis B now published in @cellpress.bsky.social
From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵
www.cell.com/cell/fulltex...
💊 Drug development relies on understanding gene function.
However, we still don’t know what most genes actually do.
Excited to be part of the #MorPhiC consortium, working to close this knowledge gap. #ScienceMatters #CRISPR #FunctionalGenomics #iPSC
Check out 👇
www.nature.com/articles/s41...
Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic.
globalnews.ca/news/9793403...
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
We've summarised the landscape of human pluripotent stem cell trials worldwide in a review in Cell Stem Cell. Fun fact: Over 1200 patients have to date received treatment with hPSC products in 116 different trials, and more than 100 billion hPSC-derived cells have been dosed! doi.org/10.1016/j.st...
