Barbara Pernaute's Avatar

Barbara Pernaute

@bpernaute

Developmental biologist. Group Leader @cabd-upo-csic.bsky.social

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18.11.2024
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Latest posts by Barbara Pernaute @bpernaute

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πŸ“£ We are looking for new colleagues πŸ”¬πŸ§¬πŸ§ͺ

The @lmcb-ucl.bsky.social at University College London @ucllifesciences.bsky.social are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.

02.03.2026 17:49 πŸ‘ 12 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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🚨🧬🚨

We're looking for a specialized Research Assistant to spearhead a project aimed at exploring new RNA therapeutics in diabetes and other metabolic disorders.

Junior or Senior, we're hoping to recruit a highly motivated and self-driven scientist interested in both basic and applied science. πŸ¦„

02.03.2026 16:07 πŸ‘ 7 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0
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Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs Nature Structural & Molecular Biology - METALoci, a new three-dimensional genome computational tool, reveals a major rewiring of regulatory interactions during sex determination. By combining...

🀩πŸ’ͺ Out now! 3D regulatory hubs in sex determination

With @mamartirenom.bsky.social & Capel labs, led by @imotagom.bsky.social & @jrotwitguez.bsky.social

1️⃣ METALoci – explore #3DGenome 🧬
2️⃣ Non-coding region controlling Fgf9 🧩
3️⃣ Meis genes = new key players 🌟

πŸ‘‰ rdcu.be/e5sm2

1/n Bluetorial πŸ‘‡

24.02.2026 14:02 πŸ‘ 59 πŸ” 26 πŸ’¬ 1 πŸ“Œ 2
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🚨🚨 #Hiring!

Funded #phd position open in our lab @cabd-upo-csic.bsky.social to study the role of YAP1 and associated factors in #preimplantation embryo development.

πŸ“† Apply by 6th March 2026 Details below.

@sebioldev.bsky.social

Please RT!

20.02.2026 13:58 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com

09.12.2025 17:44 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 2

Last days to apply! Cool project, cool cities! :-)

(Please repost! πŸ™)

22.09.2025 07:04 πŸ‘ 12 πŸ” 16 πŸ’¬ 0 πŸ“Œ 0
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Very happy to share the work of Huanhuan Li et al. While not a natural embryo, you might not have known that if I hadn’t told you. (1/3)

07.08.2025 15:58 πŸ‘ 14 πŸ” 8 πŸ’¬ 3 πŸ“Œ 0
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Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs Hanna and colleagues show that signaling pathway modulation amplifies the inherent flexibility of genetically unmodified mouse naive PSCs to adopt extra-embryonic cell fate potential. This endows them...

1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells".

www.cell.com/cell-stem-ce...

07.08.2025 15:29 πŸ‘ 41 πŸ” 15 πŸ’¬ 2 πŸ“Œ 0
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Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease - Nature Reviews Molecular Cell Biology Transposable elements (TEs) comprise nearly half of the human genome. This Review discusses transcriptional and post-transcriptional mechanisms that repress TE activity, how TEs escape this suppressio...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease.
www.nature.com/articles/s41...

30.06.2025 13:11 πŸ‘ 142 πŸ” 69 πŸ’¬ 2 πŸ“Œ 3
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⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.

23.06.2025 07:51 πŸ‘ 124 πŸ” 45 πŸ’¬ 4 πŸ“Œ 7
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How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story:
www.cell.com/cell-host-mi...

18.06.2025 17:11 πŸ‘ 108 πŸ” 31 πŸ’¬ 5 πŸ“Œ 8
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Los cursos de verano en #olavidecarmona son πŸ”

Nuestras compaΓ±eras @anafminan.bsky.social , Sol Sotillos y @proteolaura.bsky.social organizan el curso β€˜Modelos genΓ©ticos en investigaciΓ³n, de la bacteria al ratΓ³n’ dividido en dos partes!

Info ‡️
www.upo.es/formacionper...

www.upo.es/formacionper...

13.05.2025 08:12 πŸ‘ 2 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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🚨🚨#Hiring!

3 year #postdoc position open in my lab @cabd-upo-csic.bsky.social to study the interplay between DNA damage responses and #preimplantation embryo development. Fully funded by EARLYFATE #ERCCoG

πŸ“† Apply by 23rd May 2023

πŸ”—Details below

@sebioldev.bsky.social

Please RT!πŸ™

23.04.2025 12:45 πŸ‘ 16 πŸ” 15 πŸ’¬ 1 πŸ“Œ 4

🧐🧐🧐 Amazing course in Clinical Embryology

πŸ“Santander
πŸ—“οΈ July 28th-August 1st
πŸ’°4 scholarships available by @sebioldev.bsky.social

Counts with great line up of speakers including @bpernaute.bsky.social from #CABD

16.04.2025 18:08 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Enhanced RNA-targeting CRISPR-Cas technology in zebrafish - Nature Communications CRISPR-Cas13 RNA-targeting systems comprise an invaluable set of tools in the fields of basic and applied sciences. Here, Moreno-SΓ‘nchez, HernΓ‘ndez-Huertas, and NahΓ³n-Cano et al. enhanced the use of t...

First seen in Biorxiv and now published and updated with more data in @naturecomms.bsky.social. With this work we have further enhanced CRISPR-Cas RNA targeting in vivo using transient approaches such as RNP or mRNA-gRNA in zebrafish embryos as vertebrate model. www.nature.com/articles/s41...

16.03.2025 18:26 πŸ‘ 24 πŸ” 10 πŸ’¬ 2 πŸ“Œ 2
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Paper out !!πŸ₯³big thanks to all authors @marliesoomen.bsky.social @diego-rt.bsky.social @kaessmannlab.bsky.social @jonathangoeke.bsky.social @lorenzamottes.bsky.social & 'bluesky-less'

Lots of interesting new TE (& genes) biology

Data fully browsableπŸ’» πŸ‘‰ embryo.helmholtz-munich.de/shiny_embryo/

21.02.2025 15:50 πŸ‘ 143 πŸ” 53 πŸ’¬ 8 πŸ“Œ 2

Thanks a lot Miguel!

21.02.2025 16:41 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species

Happy to share our Slow cooked work together with @mcgregorlab.bsky.social, @posnienlab.bsky.social , @nuneslab.bsky.social sky.social and Saad Arif and the collaboration of @maikekittelmann.bsky.social, Fernando Casares & @laurensr.bsky.social and many other friends
rdcu.be/d8whP

04.02.2025 17:50 πŸ‘ 36 πŸ” 19 πŸ’¬ 2 πŸ“Œ 2

Hello early researchers! Interesting in doing a PhD in senescence, ageing and cancer? We have an open position in our lab in Spain! Please retweet or reach out if interested!

04.02.2025 11:06 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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🚨🚨🚨

If you're a bioinformatician who loves:

🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing
πŸš€ Collaborating and travelling

Apply to work with us at the spectacular BIMSB (@mdc-berlin.bsky.social) in Berlin + @upf.edu-@crg.eu in Barcelona. Qs: www.transdevolab.com

Please RT! πŸ™

23.12.2024 15:54 πŸ‘ 25 πŸ” 28 πŸ’¬ 0 πŸ“Œ 1

Thanks a lot!

08.12.2024 21:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks Sofia!!

08.12.2024 21:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Muchas gracias!!!

08.12.2024 21:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks a lot Cristina!!

08.12.2024 21:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks a lot!

08.12.2024 21:27 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks!!

08.12.2024 21:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Muchas gracias!!

08.12.2024 21:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks a lot!! 😊

08.12.2024 21:26 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks!!

08.12.2024 21:25 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Muchas gracias!!

08.12.2024 21:25 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0