alex-sneddon.bsky.social

Thrilled to announce that I've been appointed Director of the ANU Shine Dalgarno Centre for RNA Innovation. Honoured to work with a world-class team advancing RNA science. Stay tuned for more exciting updates 🚀 jcsmr.anu.edu.au/research/cen... #RNA #RNAInnovation #ANU

Thanks to our excellent team @edueyras.bsky.social and Stefan Prodic!

Resolving systematic bias in nanopore-based RNA modification detection Nanopore direct RNA sequencing has accelerated the growth of the epitranscriptomics field, yet nanopore-based RNA modification landscapes are generally unreliable due to the heuristic and unvalidated ...

New preprint 🚀 We uncover and correct systematic bias in nanopore-based RNA modification detection. ModkitOpt optimises pipelines using validated sites, increasing true positives while reducing unvalidated calls across contexts.
💻: github.com/comprna/modk...
📄: www.biorxiv.org/content/10.6...

From last year: a short video from the ARC Centre of Excellence MACSYS @macsys.bsky.social where I talk about my research on bringing domain knowledge into data-driven AI methods for complex biology