Moritz M. Reichert, MD

Excited to share that a part of my PhD work is online now on BioRxiv!

www.biorxiv.org/content/10.6...

We developed a genome editing approach to target the JAK2 V617F mutation and demonstrate its potential to alleviate MPN hallmarks in primary patient cells.

Thread 👇

Platelets sequester and harbor cell-free tumor DNA, which could enhance our ability to make early, microscopic diagnosis of cancer
@science.org

science.org/doi/10.1126/...
science.org/doi/10.1126/...

🚨 New paper alert! 🚨 I’m thrilled and proud to share that our latest work has just been published in @science.org! 🎉 🧽

📖 Read our paper here: doi.org/10.1126/sci...

🎬 Watch a summary: youtu.be/MttCA3GGWEM

🧵 Or keep reading for the key points! 🔑 1/19

Sam Altman: OpenAI will bring back GPT-4o after user backlash GPT-5 is getting roasted online.

Are we already experiencing peak AI for LLMs?
OpenAI has brought back GPT-4o, a mere day after GPT-5 was released (mashable.com/article/sam-...).
Will we see developments in small increments only, as we are seeing in the smartphone world?
#ai #llm

De novo-designed pMHC binders facilitate T cell–mediated cytotoxicity toward cancer cells The recognition of intracellular antigens by CD8+ T cells through T cell receptors (TCRs) is central for adaptive immunity against infections and cancer. However, the identification of TCRs from patie...

Brilliant work by Johansen et al. establishing a strategy to predict class I-reactive TCRs and designing pMHC binders www.science.org/doi/10.1126/...

Fantastic! Could you add me as well?