AdMOSC Research

The classic table of E1 vs E2 vs SN1 vs SN2. Hopefully it is useful in giving UG students an idea of what mechanism might be in operative and answering some of those annoying exam questions (reality sucks, and it is highly likely that multiple mechanisms will be operating at the same time!).

The obligatory summary of a summary and a table of E1 vs E2 vs Sn1 vs Sn2. Hopefully, this is of use to some, but if I'm brutally honest, it was just a quick stop gap while I work on more fun #ChemEd #Chemistry #ChemSky summaries (currently writing ones on cycloadditions and rearrangements).
Cheers

Our next step applying non-statistical self-assembly to ⚡️light-driven charge separation in @angewandtechemie.bsky.social ! Donors and acceptors in heteroleptic coordination cages, electrochemistry, time-resolved spectroscopy!
@grk2376.bsky.social @solvationsci.bsky.social
doi.org/10.1002/anie...

Excited to share our latest publication in #ChemEurJ on fluorescence sensing in water, featuring newly designed sulfonatocalixarene–pyrene conjugates. Congratulations to Dr. Joana Martins, who recently earned her PhD, for this excellent work!
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

🌍 ¿Formas parte del #CSIC y te gustaría realizar una estancia en centros de Investigación, tecnológicos, museos o administraciones de Iberoamérica? 

👩‍🔬👨‍🔬 Consulta la convocatoria de ayudas de movilidad del #CSIC con la Fundación Carolina

 ➡️ http://tiny.cc/pyox001

Our next vMASC seminar will be from:

• Xavi Ribas (QBIS-CAT)

• Subhasis Chattopadhyay (Masaryk University, Czech Republic)

Date 📆 and time 🕰️: Thursday 29th January 2026 at 14:30 (UK time)

Register at mascgroup.co.uk/vmasc-4 to attend!

#RSC_MASC
#vMASC

Elements of successful NIH grant applications | PNAS Is there a formula for a competitive NIH grant application? The Serenity Prayer may provide one: "Grant me the serenity to accept the things I cann...

The core ideas are applicable to many successful proposal types for funding beyond NIH.

www.pnas.org/doi/10.1073/...

Join us at The Open University, Milton Keynes on the 15th and 16th of December 2025 for this year’s RSC Macrocylic and Supramolecular Chemistry meeting!

Registration and abstract submission are now open (key deadlines below)

More on mascgroup.co.uk/masc-2025-ho...

#RSC_MASC
#RSC_MASC_2025

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Our work on the unidirectional motion of a CD is now in the September issue of Chem and on the cover!
Many thanks to the whole team and @cp-chem.bsky.social for the highlight!
@ipcm-sorbonne.bsky.social @msollogoub.bsky.social @enxuliu.bsky.social

www.cell.com/chem/fulltex...

Great collaborative meeting today at @cabd-upo-csic.bsky.social .

Proud of this new preprint on ML-assisted Computational Workflow to the Robust Modeling of Supramolecular Metallacages in Solution | ChemRxiv - doi.org/10.26434/che...

🥳So excited to see our work highlighted #OnTheCover of @angewandtechemie.bsky.social (Outside Back Cover)!!
Many thanks to Jo Richers Studio for designing this beautiful piece of art!🤩

👀Check out the full story here:
doi.org/10.1002/anie...

#ProudPI
#SupramolecularChem
#ChemTwitter
#WomenInSTEM

vMASC Call to volunteer for the vMASC committee vMASC: Expression of interest to volunteer for the vMASC committee The organising committee of the virtual Macrocyclic and Supramolecular Chemistry We are inviting members of the vMASC community to…

📣 Call for Volunteers - vMASC 📣

Submit your expression of interest to join the vMASC organising committee!

Deadline 📆 18th Aug 2025

Eligibility: full-time researcher (including early career) + member of RSC MASC Interest Group

Find out more on mascgroup.co.uk/vmasc-4/vmas...

It was a fantastic experience to form part of team of this ambitious project, bringing quality #science to people traditionally forgotten by classical outreach events. Many thanks to all the people that made it possible!!

Atropisomeric carbon-rich macrocycles: Synthesis, structural evolution, and properties

doi.org/10.1016/j.cc...

🤗 We welcome Samwel Emanuel Samwel to our group. He is an @euerasmusplus.bsky.social student of #biotechnology from #Poznan University of Life Sciences (Poland) who will study molecular interactions between small drugs and carrier #proteins to improve their therapeutic formulation. #chemistry

Excited to see our Collection on Mechanically Interlocked Molecules now published in @commschem.nature.com! It’s been a pleasure to edit this with @fschaufelberger.bsky.social and Serena Silvi. Grateful to all authors for their excellent contributions—lots of great science to explore! #ChemSky #MIMs

🤩🤩🤩Super happy with our recent Trends in Chemistry @cp-trendschem.bsky.social review where we analyze the recent emerging applications of #MolecularCages

We also provide a glossary with concepts useful for those new in the field

IDM at @upv.es

📰DOI: doi.org/10.1016/j.tr...

Full paper 👇👇👇

Tailoring Tubular Supramolecular Polymers with Polar Lumens to Host Hydrophilic Dye Molecules A unique class of tubular polymer structures that are soluble in apolar organic solvents but are endowed with polar pores has been created through the rational design of the monomer units, which self...

Thrilled to share our recently published work!
onlinelibrary.wiley.com/doi/10.1002/...

PhD Position Offer We are looking for a highly motivated PhD candidate to join the Montenegro Lab and carry out a doctoral thesis focused on the synthesis, functionalization, and evaluation of boron clusters and chaotro...

🔊 We are looking for a motivated PhD candidate to work @ciqus.bsky.social in drug delivery by superchaotropic boron clusters.

We offer a great working environment, in an excellent center and an exciting research field, www.nature.com/articles/s41...

euraxess.ec.europa.eu/jobs/360505
Sharing 🙏

Reaction with #boron trifluoride leads to the corresponding #aza-BODIPYs, induces a stereochemical inversion that destroys the helix, flattens the system and switches on #fluorescence.

#Organic #Synthesis

We report aza-dibenzodipyrromethenes with an interesting architecture where the core adopts a helical arrangement, placing terminal aromatic fragments directly on top of each other in close, p-stacked arrangement. Symmetrical and unsymmetrical derivatives can be afforded with a controlled approach.

A Family of Symmetrical and Unsymmetrical Aza‐Dipyrromethenes and Aza‐BODIPYs with Through‐Bond and Face‐to‐Face p‐Interaction Between Termini The dipyrromethenes (DPMs) and their borylated adducts (BODIPYs) constitute a class of versatile chromophores that has become one of the most widely studied over recent decades. They combine excellen....

➰ Helical symmetrical and unsymmetrical aza-dipyrromethenes and related aza- #BODIPYs. Our latest work with Andy Cammidge's group at the @uniofeastanglia.bsky.social has been published in @chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#chemistry #research

Great to see our Review on using Peptides to build Discrete Supramolecular Architectures online at Angewandte @angewandtechemie.bsky.social ! onlinelibrary.wiley.com/doi/10.1002/... with a great Frontispiece from Ben! Congratulations Ben Ellen and Leah!

Structural control of dynamic covalent cages: kinetic vs. thermodynamic assembly and PFAS removal from water Dynamic covalent chemistry is a powerful tool to synthesise complex structures from simple building blocks. However, even minor variations in the numerous parameters governing self-assembly can drasti...

Structural control of dynamic covalent cages: kinetic vs. thermodynamic assembly and PFAS removal from water using our novel dynamic covalent Tri2Tri2 cages!

Check it out now in @chemicalscience.rsc.org, if you like 👀
@hhu.de
pubs.rsc.org/en/content/a...

Next-generation materials for nucleic acid delivery - Nature Reviews Materials Efficient and targeted delivery of nucleic acids is critical for realizing the full therapeutic potential of gene editing, vaccines and RNA-based drugs, and emerging delivery platforms offer innovativ...

Next-generation materials for nucleic acid delivery! Now in @natrevmats.nature.com Our viewpoint on the future synthetic carriers for therapeutic nucleic acids.
Read it here: www.nature.com/articles/s41...

What if complexity was already built in — just waiting to be released?
In our latest @science.org, we show how COFs can selectively excise organic macrocycles with precision.
A chemistry that reveals what’s already there. Clip-off Chemistry.
Link: www.science.org/doi/10.1126/...

Two for one mechanophore!

4-membered ring mechanophores broken 2 ways with a rotaxane actuator for the generation/release of diverse functional molecules!

Great work from Lei Chen now as a #VIPaper in
@angewandtechemie.bsky.social

onlinelibrary.wiley.com/doi/10.1002/...

#chemsky #OA

bsky.app/profile/vtem...

Really nice work on macrocyclic supramolecular chemistry.

Tuning Antiaromaticity Through Meso‐Substituent Orientation in Core‐Modified Isophlorins The antiaromaticity of dithiadioxaisophlorins is controlled by the steric bulkiness of meso-substituents through their tilt angle relative to the macrocycle. Bulkier substituents maintain larger angl....

When Maika synthesized thienyl-substituted isophlorins for another purpose, she noticed they showed weaker antiaromaticity than others. This sparked our investigation into the relationship between substituents and antiaromaticity using both synthesis and computation.
DOI: 10.1002/ajoc.202500372 (OA)