Dr Wayne Cottrell & Co

Barnsley rabies death could change disease notification rules Doctors treating Yvonne Ford struggled to diagnose her before being told about holiday dog scratch.

Very sad reminder of the importance of getting a travel history #IDSky

www.bbc.co.uk/news/article...

FDA reverses course, agrees to review Moderna’s flu vaccine The FDA reversed course and told Moderna it would review its application for a new flu vaccine, the company announced Wednesday.

“The Food and Drug Administration reversed course and told Moderna it would review its application for a new flu vaccine… The FDA will now review the product in adults 50 to 64 through a regular pathway, and adults over 65 via accelerated approval with a requirement to run a post-marketing study.”

Excruciating tropical disease can now be transmitted in most of Europe, study finds ‘Shocking’ data shows the climate crisis and invasive mosquitos mean chikungunya could spread in 29 countries

www.theguardian.com/science/2026...
Excruciating tropical disease can now be transmitted in most of Europe, study finds

London measles outbreak: more than 60 children infected Cases are spreading between children in Enfield as the virus exploits low MMR vaccination rates, medical experts say

London measles outbreak: more than 60 children infected

Cases are spreading between children in Enfield as the virus exploits low MMR vaccination rates, medical experts say

www.thetimes.com/uk/...
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The shingles vaccine may have a dementia upside Research suggests it could prevent and slow the progress of cognitive decline

The shingles vaccine may have a dementia upside ft.trib.al/0XWJF0W | opinion

Key public health message What did you want to address in this study and why? Women in Denmark who were vaccinated in 2008 against human papillomavirus (HPV) as girls (~14 years) have reached screening age. Compared with previous generations, these women are expected to have a considerably lower risk of cervical cancer and it is pertinent to assess the new generations’ future need for screening. We tested up to three consecutive cervical cell samples of Danish women (22–30 years) vaccinated as girls, collected between 2017 and 2024. What have we learnt from this study? Infection with HPV types covered by the vaccine (HPV16/18) has been almost eliminated. Before vaccination, the prevalence of HPV16/18 was between 15–17%, which has decreased in vaccinated women to < 1% by 2021. However, about one-third of women still had HPV infection with non-vaccine high-risk HPV types, and new infections with these types were more frequent in vaccinated than in unvaccinated women. What are the implications of your findings for public health? The HPV vaccine has been effective in reducing infections with vaccine-covered HPV types (HPV16/18), the HPV types responsible for over 70% of cervical cancer. Still, the high but steady proportion of women infected with high-risk HPV types not covered by the vaccine indicate a need for less intensive but continued screening of these generations.

HPV is the most common sexually transmitted infection & main cause of #cervicalcancer

Widespread #vaccination could prevent 90% of cervical cancer

Denmark shows it’s works: the main cancer-causing #HPV strains are now nearly eliminated among vaccinated women

#WorldCancerDay 👉 bit.ly/EUS3027HPV

Well now, would you look at that? A massive, 4-YEAR-LONG study of NEARLY 30 MILLION people in France found that individuals who received a COVID-19 mRNA vaccine had a 74% LOWER risk of death from severe COVID-19 compared to unvaccinated individuals and ZERO increased risk of all-cause mortality.

People don't understand just how terribly bad this is going to be (and already is). Right now the people I talk to about this have the reaction of "yeah, can't believe these anti-vaccine parents, they're just nuts. Glad me and my kids are vaccinated" 1/6

Scientists in France assess antibiotic resistance in people who use doxycycline post-exposure prophylaxis (doxyPEP)

A French study with gay / bi men found gonorrhea less susceptible to some antibiotics among those taking doxyPEP (using the antibiotic doxycycline to prevent syphilis and chlamydia).

Info on type 2 diabetes: risks(obesity, inactivity, age, family history, high blood pressure), diagnosis(plasma glucose, hemoglobin A1c), treatment(diet, exercise, meds like metformin, bariatric surgery). Blood glucose monitoring shown.

Type 2 #diabetes is a condition of elevated blood glucose levels that may cause serious health consequences including vision loss, heart disease, stroke, nerve damage, and kidney failure.

📄 Learn more in this JAMA Patient Page:

ja.ma/4byUpMs

Universal nirsevimab slashes RSV infant hospitalizations, study suggests

Great to see two papers out that show the benefits of RSV vaccination (monoclonal treatment) to prevent severe RSV infection. A quick thread to unpick what these vaccines are as there are 2 quite different products in clinical use and it can be confusing what the terminology means. #HealthPolicy 🧵

First leukaemia patient to get pioneering drug on NHS says it is 'very sci-fi' Oscar Murphy has an aggressive form of the blood cancer and is the first to get CAR-T therapy in the UK.

"CAR-T therapy has been available on the NHS for several years for certain types of leukaemia and lymphoma but has only now been extended to adults with B-cell ALL."

#genetherapy #celltherapy

www.bbc.co.uk/news/article...

Diagram explaining uveitis, an inflammation of the eye's uvea. It shows eye anatomy, uveitis types (anterior, intermediate, posterior, panuveitis) and their symptoms like redness and blurry vision. It lists treatments and potential complications if untreated.

Uveitis is a condition involving inflammation in the uvea (the middle portion of the eye).

This JAMA Patient Page describes types of uveitis, ages and conditions associated with uveitis, and diagnosis and treatment.

ja.ma/4qVe8uo

Ban Conversion Practices (I’m a Steering Committee member) graphic: Text: Nearly one in six LGBTQ+ young people in the UK reported being threatened with or subjected to conversion practices.

Today is International Day to End Conversion Therapy (aka #IDECT).
Conversion practices are ineffective, unscientific and cause actual harm.
Governments since 2017 have promised to bring forward a ban - but we’re still waiting.
Keep the pressure on.
Get all LGBTQ conversion practices banned in 2026.

Terrence Higgins Trust CEO: 'Why 2026 must be the year we unlock PrEP through community pharmacies' (EXCLUSIVE) "We have the tools, the evidence and the opportunity. Now we need the courage to act," Richard Angell OBE writes for Attitude.

#PrEP prevents HIV acquisition.
110,000 people are currently on it in England but some communities (black women, people in rural communities) are underserved.
To end the epidemic, all must have access.
Getting PrEP into pharmacies would make it easier for many.
This is the urgent goal for 2026.

GOOD NEWS! Researchers have shown Alzheimer’s disease can be REVERSED- not just prevented. Using a potent neuroprotective compound called P7C3-A20, they found RESTORING balance to a central cellular energy molecule (NAD+) not only PREVENTED disease features but REVERSED them, EVEN at late stages.

Researchers at MD Anderson discovered a promising therapeutic pathway for a challenging subtype of acute myeloid leukemia that uses a combination of therapies.

Read more: spr.ly/63320CeB4E #OncSky #EndCancer

Vaccination remains THE key intervention against severe disease, hospitalization, and death. Make sure you are protected and wear a mask. 🧪🧵⬇️

230,000 Deaths and the ‘Calculated Silence’ of the Medical Establishment About the COVID Inquiry The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello

Hard-hitting truth-telling from UCL Prof Anthony Costello….

“The Covid Public Inquiry is a devastating critique of medical advisers, civil servants and politicians who led the UK to the worst public health disaster in a century. More than 230,000 deaths.”

www.bylinesupplement.com/p/230000-dea...

Today, the Government unveiled the new HIV Action Plan for England, backed by £170 million.

This marks a pivotal moment in shifting the dial in the HIV response.

Please read BASHH's response below ⬇️

Diagram showing CAR T-cells and T-cell therapies for cancer. It details the structure of chimeric antigen receptors, engineered CAR T-cells targeting tumor antigens, and tumor-infiltrating lymphocytes.

🧬 CAR T treatments improve overall survival for patients with large B-cell lymphoma and progression-free survival for patients with multiple myeloma.

Save this Review for your bibliography:
ja.ma/49HHc34

GOOD NEWS! Researchers have made a HUGE breakthrough towards a UNIVERSAL antiviral. By targeting sugar molecules found on the surface of many viruses that SHARE structural similarities, they identified FOUR compounds that successfully BLOCKED infections from SEVEN different viruses.

Experimental mRNA flu vaccine shows superior efficacy against symptomatic illness

Two exciting phase two trials show incredible success of mrna vaccines for seasonal flu with infectious symptoms prevented in some healthy individuals. 🧪🧵

#VaccinesWork