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Dervis Salih

@dervissalih1

Scientist studying molecular links between Alzheimer's, Ageing, microglia & diet @UCL @UKDRI @ARUKnews #Dementia Trained @BabrahamInst @Cambridge_uni @Stanford

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Latest posts by Dervis Salih @dervissalih1

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08.03.2026 12:40 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The England result was not an accident the #KingsOfTheNorth #Scotland #SCOFRA #SixNations

07.03.2026 21:04 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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It must be Love ❀️

14.02.2026 22:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Movers & Shakers: The funny side of Parkinson's The award winning podcast about living with Parkinson’s is back and for the first episode of the new series of Movers and Shakers we have a treat for you.

It’s back! And the first episode of the new series of #MoversAndShakers iscabout the new sitcom with the Parkinson’s theme open.substack.com/pub/rorycell...

17.01.2026 10:08 πŸ‘ 205 πŸ” 20 πŸ’¬ 1 πŸ“Œ 1
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Internet killed the Video Star: Ended their final broadcast with 'Video killed the radio star' by The Buggles, the same as the very first video broadcast on 1st August 1981

03.01.2026 22:17 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Experimental design for LIBD LFF Spatial ERC project

Experimental design for LIBD LFF Spatial ERC project

Excited to share our latest preprint from @lieberinstitute.bsky.social spatial + single-cell RNA-seq map the ERC & explore how AD risk shapes gene expression doi.org/10.1101/2025...
Our major finding: β€œAPOE E4 Alzheimer’s Risk Converges on an Oligodendrocyte Subtype in the Human Entorhinal Cortex”

11.12.2025 12:13 πŸ‘ 26 πŸ” 12 πŸ’¬ 1 πŸ“Œ 1
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Happy New 2026! The year AI really kicks in. But which side are you on? #SKYNET

01.01.2026 22:52 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

2025 not a great year for music, but this was a clear standout track. Fitting that it's about doing nothing or recovery. Stylish and mature, in many ways a classy template for alternative rock @wolfalicefans.bsky.social

31.12.2025 19:27 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Back at the hospital for my post-cataract op check up and very happy to see that my data will be used in research

30.12.2025 08:37 πŸ‘ 512 πŸ” 4 πŸ’¬ 5 πŸ“Œ 0
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Not the Xmas movie I was expecting, but a fine Xmas movie eitherway. I won't feel the same hearing the songs "The Air That I Breathe" or "Creep" ever again #Heretic #christmasmovies

28.12.2025 21:15 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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25.12.2025 13:46 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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25.12.2025 13:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Neurodevelopmental Disease-causing Variants in Choline Kinase CHKA Gene Couple Phosphatidylcholine Synthesis to Oxidative Stress Damage and Disease Etiology Biallelic variants in CHKA, which encodes the first enzyme in the CDP-choline pathway for the synthesis of phosphatidylcholine, cause an inherited disorder characterized by epilepsy, microcephaly, and...

We previously characterised recessive CHKA-related developmental & epileptic encephalopathy. This new work shows patient-derived cells have disrupted Kennedy pathway activity, mitochondrial dysfunction and oxidative stressβ€”partially rescued by mitochondrial uncoupling. www.jbc.org/article/S002...

23.12.2025 11:14 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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It so easy to walk past and ignore the #Homeless But look up @bbbanksy.bsky.social

22.12.2025 23:45 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Long COVID involves activation of proinflammatory and immune exhaustion pathways @natimmunol.nature.com
www.nature.com/articles/s41...

13.12.2025 04:23 πŸ‘ 15 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Amazing title song from Mr Jones too

10.12.2025 23:17 πŸ‘ 7 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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That’s a wrap on Connectome 2025! πŸ‘

Today has been another fantastic day, with special thanks to our keynote Prof Christian Haas, and Charles Sabine OBE who gave a powerful talk about his lived experience of Huntington's disease.

Thank you to everyone who made it such a great event!

10.12.2025 16:32 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Our annual conference, Connectome, is in full swing today!Β 

As well as excellent science talks, this morning we heard an insightful discussion between Prof Siddharthan Chandran, Prof Miratul Muqit, and journalist @rorycj.bsky.social, who generously shared his experience of living with Parkinson's.

09.12.2025 13:53 πŸ‘ 10 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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"Sympathy... is one of the noblest virtues with which man is endowed" Darwin. Amazing to hear the experience of Charles Sabine, diagnosed with Huntington's disease. Really reinvigorates why we choose the hard path of science @ucl-hd.bsky.social @ukdri.ac.uk @uclqsion.bsky.social

10.12.2025 18:52 πŸ‘ 7 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Dear @rorycj.bsky.social I deeply appreciate your commitment to Parkinson's disease and wish all affected patients and their families significant progress in the near future.

09.12.2025 13:08 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Great to speak to top brain scientists. (I mentioned the post I wrote about Elon Musk headlined Bonkers but Brilliant)

09.12.2025 12:21 πŸ‘ 154 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Great to hear from the Brilliant @rorycj.bsky.social on the fight against Parkinson's. Certainly Brilliant, not Bonkers @uclbrainscience.bsky.social @uclqsion.bsky.social @ukdri.ac.uk

09.12.2025 10:51 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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Great to be at Dementia Research Institute annual meeting. Lots of great science @ukdri.ac.uk @uclqsion.bsky.social

09.12.2025 10:29 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Radiohead break the attendance record at London's The O2 – as they raised money for Samaritans and grassroots venues Radiohead have broken the attendance record at The O2, and shows have raised money for grassroots music venues and MΓ©decins Sans FrontiΓ¨res.

Radiohead break the attendance record at London’s The O2 – as they raised money for Samaritans and grassroots venues
www.nme.com/news/music/r...

29.11.2025 17:41 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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a man wearing glasses is holding a cup of coffee and laughing . ALT: a man wearing glasses is holding a cup of coffee and laughing .
22.11.2025 21:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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"Theatricality and deception - powerful agents to the uninitiated." "Oh, you think darkness is your ally." "The shadows betray you because they belong to me." Joe Marler was the ONLY one that worked it out #CelebrityTraitors

07.11.2025 20:22 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 1

trickle down economics
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01.11.2025 01:31 πŸ‘ 21426 πŸ” 5252 πŸ’¬ 456 πŸ“Œ 258

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1

28.08.2025 16:15 πŸ‘ 4 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
01.11.2025 13:32 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

TDP-43 loss of function drives aberrant splicing in Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.09.04.673943v1

09.09.2025 19:16 πŸ‘ 8 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0