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Florent Mouliere

@florentmouliere

Team leader at CRUK National Biomarker Centre, University of Manchester. https://cruknbc.org/research/nucleic-acids-biomarkers/ #liquidbiopsy #cfDNA #EV #multiomics

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17.11.2024
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Latest posts by Florent Mouliere @florentmouliere

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Online now! Cell-free DNA #methylome and #fragmentome analysis for relapse monitoring of #EwingSarcoma

By S. Richardson, M. McCabe, @florentmouliere.bsky.social & colleagues @cancerresearchuk.org @manchester.ac.uk

➡️ doi.org/10.1038/s44321-026-00396-7

09.03.2026 20:34 👍 1 🔁 2 💬 0 📌 0

Do you know anyone keen to study cancers of unmet need and understand how to improve their responses to treatment? We are looking for a curious enthusiastic scientific officer to work at @cruknbc.bsky.social , close ties with @manchester.ac.uk and @christieinstitute.bsky.social

28.02.2026 17:59 👍 4 🔁 3 💬 1 📌 0
lab to life

lab to life

Exciting conference alert!

sites.manchester.ac.uk/from-lab-to-...

Fantastic speakers including Chris Marine, Christian Blank

Melanoma evolution
Local microenvironment of melanoma
Melanoma-host interactions
Precision immunotherapy
Emerging therapeutics
Clinical trials and real-world data

22.01.2026 23:28 👍 5 🔁 5 💬 0 📌 0
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@alexdickinson, not on Bluesky, on the concerns he has about the performance of the Grail Bio $GRAL MCED Galleri test

30.10.2025 07:53 👍 3 🔁 3 💬 1 📌 0
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You've got just a few days left to submit your proposal to join us as a new Group Leader

📅 Applications close 2nd November

Package includes:

🪙Multi-year funding
🧪Core Facility Access
🥼 #Postdoc & #PhD positions
🤝Mentorship

Visit our website to apply:
www.cruk.manchester.ac.uk/career/new-g...

30.10.2025 11:47 👍 10 🔁 13 💬 1 📌 1

Along with this example from @cruk-ci.bsky.social, we contributed to the recent @crukpolicy.bsky.social report on how UK immigration policy is negatively affecting international recruitment of cancer researchers

Read the full story in @theobserveruk.bsky.social here: observer.co.uk/news/nationa...

29.08.2025 07:55 👍 8 🔁 4 💬 0 📌 0
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Research Technician:Oxford Road

The Lee lab is expanding! We are really interested in mechanisms of local and systemic immune tolerance particularly in liver metastases - X2 research technicians
💡 Creative fun environment
🌱 Opportunities to grow
🫂 Highly collaborative with clinical+basic research
📢 Please spread word!

22.08.2025 16:02 👍 7 🔁 5 💬 1 📌 1
An image of three brightly lit, glowing green bottles with an empty space for a fourth bottle, as part of a flow cytometry machine

Text says "New Job openings - See all recruitment opportunities by visiting https://www.cruk.manchester.ac.uk/careers/"

An image of three brightly lit, glowing green bottles with an empty space for a fourth bottle, as part of a flow cytometry machine Text says "New Job openings - See all recruitment opportunities by visiting https://www.cruk.manchester.ac.uk/careers/"

We are recruiting to a variety of roles, check out our Careers pages for all the details of research and operations positions including:

🥼 Scientific Officer
💻Computational Immunologist
🧪 Laboratory Aide
📝 Executive Assistant

www.cruk.manchester.ac.uk/careers/

Join us to advance #Cancer Research

15.08.2025 16:36 👍 5 🔁 3 💬 0 📌 0
Photograph shows three researchers in Cancer Research UK lab coats looking at a folder of documents in a laboratory in the Paterson Building

Text says: Join our Team - We're currently recruiting both research and operations positions

Scientific Officer - MI/25/32 
Computational Immunologist - MI/25/17_2
Executive Assistant to Institute Director - MI/25/44

Photograph shows three researchers in Cancer Research UK lab coats looking at a folder of documents in a laboratory in the Paterson Building Text says: Join our Team - We're currently recruiting both research and operations positions Scientific Officer - MI/25/32 Computational Immunologist - MI/25/17_2 Executive Assistant to Institute Director - MI/25/44

We are recruiting!

🥼 Scientific Officer to work with @drwilliamhill.bsky.social
💻 Computational Immunologist in the lab of @santiagozelenay.bsky.social
📝 Executive Assistant to our new Institute Director Prof Samra Turajlić @turajliclab.bsky.social

Details at:
www.cruk.manchester.ac.uk/careers/

08.08.2025 12:35 👍 7 🔁 8 💬 0 📌 0
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We are hiring an #ExecutiveAssistant to support our new Institute Director, Prof Samra Turajlić

Apply online today at: apps.cruk.manchester.ac.uk/recruitment/...

Starting Salary: Circa £40,000 per annum
Closing Date: 28/08/2025
Duration of Post: Permanent
Job Ref: MI/25/44

04.08.2025 12:32 👍 3 🔁 2 💬 0 📌 2
Job vacancy: Clinical Research Fellow, The Christie NHS Foundation Trust, Manchester | trac.jobs

⭐We have a clinical fellow opportunity with the melanoma team! ⭐

Very friendly and supportive team
Lots of learning opportunities including clinical trials and immune therapy

Apply here👇

urldefense.com/v3/__https:/...

30.07.2025 14:29 👍 1 🔁 1 💬 0 📌 0
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Vacancy: Postdoctoral Scientist - National Biomarker Centre We are recruiting a Postdoctoral Scientist to develop a multimodal Liquid Biopsy for improving the detection and understanding of colorectal cancer.

We have a position open for a postdoctoral researcher. This is a unique opportunity to develop #liquidbiopsy methods to non-invasively analyse colorectal cancer plasticity and response to treatments. The position is part of the CRC-STARS consortium. @cruknbc.bsky.social cruknbc.org/vacancy-post...

13.05.2025 14:13 👍 4 🔁 5 💬 0 📌 0
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Cell-free DNA methylome and fragmentome analysis for disease relapse monitoring in patients with Ewing Sarcoma Liquid biopsies and cell-free DNA (cfDNA) offer minimally invasive methods for the diagnosis and monitoring of Ewing Sarcoma (EwS). EwS have a low tumour mutational burden and their detection with pla...

Just released on MedRxiv, our new study led by Sophie Richardson analysing plasma cfDNA methylome and fragmentome for tracking relapse in patients with Ewing sarcoma. @cruknbc.bsky.social #liquidbiopsy #cfDNA www.medrxiv.org/content/10.1...

29.04.2025 08:47 👍 2 🔁 0 💬 0 📌 1
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Challenges of small cell lung cancer heterogeneity and phenotypic plasticity - Nature Reviews Cancer In this Review, Simpson et al. summarize the emergent understanding of molecular subtypes of small cell lung cancer (SCLC). They discuss how intratumour heterogeneity and dynamic tumour plasticity may challenge the success of immune and molecular subtype-targeted therapies and argue that combination therapies, monitored by serial liquid biopsy-based biomarkers, will be needed to improve the outcomes of patients with SCLC.

🐰#Weekendrreading #Review🚨

Caroline Dive&Co discuss the challenges associated with #ITH and plasticity in #SCLC and argue that combination therapies&liquid biopsy-based biomarkers are needed to improve patient outcomes.
📖⬇️
@cruk-mi.bsky.social

17.04.2025 13:47 👍 10 🔁 5 💬 0 📌 1
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Vacancy: Senior Translational Scientist - National Biomarker Centre An exciting opportunity has arisen for a Senior Translational Scientist to join the Nucleic Acids Biomarker (NAB) team of the NBC.

We have a position open in the lab @cruknbc.bsky.social for a Senior Translational Scientist. If you like #cfDNA #liquidbiopsy, translational research, and their growing range of clinical applications, this job is for you! cruknbc.org/vacancy-seni...

13.02.2025 10:56 👍 5 🔁 4 💬 0 📌 1
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📣 We have an exciting opportunity for a 𝗦𝗲𝗻𝗶𝗼𝗿 𝗧𝗿𝗮𝗻𝘀𝗹𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁 to join our 𝗡𝘂𝗰𝗹𝗲𝗶𝗰 𝗔𝗰𝗶𝗱𝘀 𝗕𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿 (𝗡𝗔𝗕) 𝘁𝗲𝗮𝗺 led by Dr @florentmouliere.bsky.social

For more information & to apply visit -> cruknbc.org/vacancy-seni...

12.02.2025 17:01 👍 1 🔁 1 💬 0 📌 0

Okey dokey here goes! First real post - please reshare if appropriate 🙏

🔔We’ve got two postdoc level positions opening in our lab! One wet lab, one computational🔔

We’re a scientifically diverse, friendly bunch working at the interface of mitochondrial biology, metabolism & cancer in Glasgow, UK.

07.01.2025 17:13 👍 7 🔁 9 💬 2 📌 0
Background image shows a photograph of the Paterson Building at sunrise, with pink tints on the windows, and the Oglesby Cancer Research Building on the left of the photograph.

Text says "Position Available: Recruitment Officer Human Resources Department" and "Apply now to join our team"

Background image shows a photograph of the Paterson Building at sunrise, with pink tints on the windows, and the Oglesby Cancer Research Building on the left of the photograph. Text says "Position Available: Recruitment Officer Human Resources Department" and "Apply now to join our team"

We are recruiting!

📝Are you highly organised?
💬An effective communicator?
🤝Experienced in recruitment activities?

We are looking for an in-house Recruitment Officer to support and coordinate all aspects of our recruitment

For full details, click here 👇

www.cruk.manchester.ac.uk/recruitment/...

20.12.2024 14:38 👍 3 🔁 3 💬 1 📌 0
Bicentenary PhD Studentships and Fellowships | Biology, Medicine and Health | University of Manchester Find out more about the Bicentenary PhD Studentships and Fellowships for researchers with an interest in discovery and innovation in bioscience, biomedical and health research.

⭐Opportunity alert!!⭐ funded PhD project modelling liver immune suppressive mechanisms - collaboration w Andre Freitas - BSc/MSc in computer science and experience in construction of NLP and ML models required. Msg me 4 info and pls spread the word!

www.bmh.manchester.ac.uk/study/resear...

15.12.2024 12:33 👍 3 🔁 3 💬 0 📌 0

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded

28.11.2024 09:40 👍 32 🔁 28 💬 0 📌 1
Index - CrukMi.RecruitmentHr.Ui

We also have 2 bioinformatician / computational biologist / computational scientist positions available in the lab (pre and post-doctoral level). Focus on epigenetic, transcriptomic, and ML. #cfDNA #liquidbiopsy One week left to apply! www.cruk.manchester.ac.uk/recruitment/...

18.11.2024 09:41 👍 6 🔁 4 💬 0 📌 0

A couple of days left to apply! We have a PhD position available in the lab to improve our understanding of cfDNA and cfRNA shedding from cancer cells, and the potential impact on heterogeneity. #cfDNA #liquidbiopsy #cfRNA

18.11.2024 09:37 👍 5 🔁 3 💬 0 📌 0

Hello Bluesky! Looking forward to joining this community.

18.11.2024 09:30 👍 6 🔁 0 💬 0 📌 0