Paresh Jadav

APRIL only inhibitors might be safer and more selective! #NephJC

Surrogate markers great for manuscripts but terrible for bragging rights!!
#NephJC

reported as %change in UPC and difference in geometric means — do we know how it is translated into absolute changes in proteinuria? #NephJC

still in surrogate land.. #NephJC

Paresh from Houston.
No COI.. just teaching B-cells for a decade that deposits belong in banks and not the mesangium! Yet, here we are! #NephJC #IgA

Hey #KidneyWk come find me in Houston for some free art 🖼️
(One per customer, taxes may apply, only valid 11/5-11/9, yada-yada-yada)

NephJC

#NephJC at #KidneyWk
🔥🔥We have all sorts of events

🗓️ Friday, a classic: #NephJC night- #NephJCKidney Awards,
@freelyfiltered.bsky.social
live recording + lots of fun

🗓️ Saturday, Nov 8th, 6:30 am- will start the day with a nephro run 🏃🏃

For more info 👇👇
www.nephjc.com

despite the guidelines, the local and regional practice variations, access to newer drugs, cost and availability may limit its universal implementations! #NephJC

Most cases, repeat biopsy likely not needed.. unless unexplained accelerated decline in kidney function may prompt repeat biopsy (more aggressive IS with crescentic form) or if progression is chronic in which case, additional IS can be avoided! #NephJC

it is useful in post-transplant as well IMO.
#NephJC

because even immune system knows GAMED is more fun than ABCDE. #NephJC

Hi this is Paresh from Houston. No COI.
I don't always read the guidelines, but when I do, it is after the patient has left the clinic! #NephJC

because he is in Bayou City prepping for ASN presentation:
“Invisible barrier: how to build a wall with podocytes —like a true mime”
#pokemonZA #NephSky

UPC of > 5 is significant (Repeat?) If no monoclonality, look for other smaller mol wt proteins like lysozyme(AML), Hb(hemolysis), myoglob(Rhabdo) all of which should be apparent clinically. Look for proximal tubulopathy ..as in chronic interstitial diseases. Also, rule out chyluria! #NephSky

some cities get romance movies, Houston gets true crime documentaries!. Netflix pilot in making…. lol

agree, it should be integral to all chronic illnesses research (not just CKD) especially since QOL parameters are easily standardized! And more importantly chronic illnesses are lived and not just measured! #NephJC

HRQOL data were scarce and heterogeneous! so no pooled analysis. Just qualitative data. #NephJC

17 trials with 955 patients
DAPA-CKD had 4,300 CKD patients one of half dozen CKD #Flozin trial

This is so under studied it is pathetic.
If you are going to change someone whole lifestyle you need to bring receipts

Do better dieticians

#NephJC

The only thing more restricted than protein is happiness at dinner- HRQOL #NephJC

“We promised better outcomes not better flavors” #NephJC

Thank you and look forward to the #NephJC event in Houston!

T3a
Chimerism is closer to being mainstream. This trial moves immune tolerance from a "Greek legend" to a reproducible strategy for select pts. The protocol achieved its goal, showing this isn't just single-center "magic." In what other groups would you like to see this protocol used? #NephJC

Woohoo - welcome back Paresh

The whole nephrology world will be descending on your city soon for #KidneyWk

#NephJC

T0c
There have been numerous developments in the field of transplantation that have improved outcomes and success rates. Today 95% of renal transplants are functional after 1 year, and 80% at five years. #NephJC

Hello, #NephJC
this is Paresh from Houston. No COI. Looking forward to the discussion on immune tolerance!

We are thrilled to announce that we have generously received funding for a one-year hypertension fellowship, and we are recruiting now for a candidate to start fellowship July 1, 2026 .
med.stanford.edu/hypertension/e…

-Jehan Zahid Bahrainwala
HTN Fellowship Program Director

“The great phosphate bypass” @hswapnil.medsky.social
#NephJC

Yes.. that would be awesome! Please make it happen. #NephJC

Paresh Jadav, from Houston..no COI
#NephJC

Low Urine Cr concentration: simply very poor clearance in bad AKI. (But not in steady state; as even with GFR of 5 cc/min (72L/day), creatinine excretion remains the same)
Or high water intake.. low urine Cr of 20 mg/dl who is making 4 to 5L of urine a day is having adequate clearance (1000mg)